摘要
目的:基于证素辨证对胃癌前病变(PLGC)"痰、湿"证素进行证候分析,初步建立相应的中医临床诊断规范。方法:采用横断面调查法,随机选择PLGC患者142例,运用证素理论,对提取的"痰、湿"证素单元进行调查登记探讨,研究PLGC"痰""湿"证素特征。结果:PLGC病位证素主要分布在胃、肝、脾、肾、心、胆、心神、肺等,病性证素主要分布在气滞、阳虚、气虚、湿、血瘀、痰、热、食积等;PLGC症状归纳为10组公因子,其中4组为有效公因子(F1~F4)。在PLGC中,病性证素"痰"的证素特征以形体肥胖、胸闷、咽部异物感、吐痰、舌苔腻、脉滑为主,病性证素"湿"的证素特征以环境潮湿、肢体酸重或困重、头蒙如裹、口黏腻、便溏、舌苔腻、脉滑为主。结论:明确PLGC"痰""湿"证素特征,可为临床辨别PLGC"痰""湿"证候提供参考依据。
Objective: To do dialectical syndrome analysis for the syndrome elements of ‘phlegm' and ‘dampness' extracted from precancerous lesions of gastric cancer(PLGC), and to establish the corresponding clinical diagnostic criteria for TCM preliminarily. Methods: Using cross-sectional survey method, 142 patients with PLGC were randomly selected. According to the theory of syndrome elements, the extracted syndrome elements of ‘phlegm' and ‘dampness' were investigated and registered, and the characteristics of the syndrome elements of ‘phlegm' and ‘dampness' were studied. Results: PLGC syndrome elements for disease location were mainly distributed in the stomach, liver, spleen, kidney, heart, gallbladder, heart spirit, lung,etc. The syndrome elements for disease nature were mainly distributed in qi stagnation, yang deficiency, qi deficiency, dampness,blood stasis, phlegm, heat, indigestion, etc.; PLGC symptoms were devided into 10 groups of common factors, of which 4 groups were effective common factors(F1~F4). In PLGC, ‘phlegm', as a symptom factor of disease nature, is mainly characterized by body obesity, chest tightness, foreign body sensation in the pharynx, spitting, pulse slip, and tongue greasy. And ‘dampness',as another symptom factor of disease nature, is mainly characterized by environmental wetness, heavy or trapped feeling of the body, dizziness in the head, sticky mouth, loose stool, greasy tongue, and slippery pulse. Conclusion: This paper has made clear the characteristics of ‘phlegm' and ‘dampness' syndrome elements in PLGC, which can be used as a reference for clinical identification of ‘phlegm' and ‘dampness' syndromes of PLGC.
引文
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