药物涂层球囊在冠状动脉分叉病变中的应用
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摘要
分叉病变解剖形态各异,双支架技术操作复杂,手术成功率低,再狭窄率高。为了克服药物洗脱支架的不足,药物涂层球囊应运而生。现通过分析药物洗脱支架+普通球囊、药物涂层球囊+金属裸支架、单纯药物涂层球囊在冠状动脉分叉病变中的相关临床研究进行综述。
Bifurcation lesions have different anatomical forms,complicated operation with double stents,low success rate and high restenosis rate. Drug-coated balloons were developed to overcome the shortage of drug-eluting stents. In this paper,the clinical studies of drug-eluting stent combination conventional balloon,drug-coated balloon combination bare mental stent and drug-coated balloon alone in bifurcation lesions of coronary arteries were reviewed.
Bifurcation lesions have different anatomical forms,complicated operation with double stents,low success rate and high restenosis rate. Drug-coated balloons were developed to overcome the shortage of drug-eluting stents. In this paper,the clinical studies of drug-eluting stent combination conventional balloon,drug-coated balloon combination bare mental stent and drug-coated balloon alone in bifurcation lesions of coronary arteries were reviewed.
引文
[1] Belkacemi A,Agostoni P,Voskuil M,et al. Coronary bifurcation lesions treated with the drug-eluting balloon:a preliminary insight from the DEBIUT study[J]. Euro Intervention,2011,7:K66-K69.
[2] López Mínguez JR,Nogales Asensio JM,Doncel Vecino LJ,et al. A prospective randomised study of the paclitaxel-coated balloon catheter in bifurcated coronary lesions(BABILON trial):24-month clinical and angiographic results[J].Euro Intervention,2014,10(1):50-57.
[3] Mathey DG,Wendig I,Boxberger M,et al. Treatment of bifurcation lesions with a drug-eluting balloon:the PEPCAD V(Paclitaxel Eluting PTCA Balloon in Coronary Artery Disease)trial[J]. Euro Intervention,2011,7(Suppl K):K61-K65.
[4] Herrador JA,Fernandez JC,Guzman M,et al. Drug-eluting vs. conventional balloon for side branch dilation in coronary bifurcations treated by provisional T stenting[J]. J Interv Cardiol,2013,26(5):454-462.
[5] Jim M,Lee MK,Fung RC,et al. Six month angiographic result of supplementary paclitaxel-eluting balloon deployment to treat side branch ostium narrowing(SARPEDON)[J]. Int J Cardiol,2015,187:594-597.
[6] Sgueglia GA,Todaro D,Bisciglia A,et al. Kissing inflation is feasible with all second-generation drug-eluting balloons[J]. Cardiovasc Revasc Med,2011,12(5):280-285.
[7] Burzotta F,Brancati MF,Trani C,et al. Impact of drug-eluting balloon(preor post-)dilation on neointima formation in de novo lesions treated by bare-metal stent:the IN-PACT CORO trial[J]. Heart Vessels,2016,31(5):677-686.
[8] Schulz A,Hauschild T,Kleber FX. Treatment of coronary de novo bifurcation lesions with DCB only strategy[J]. Clin Res Cardiol,2014,103(6):451-456.
[9] Kleber FX,Rittger H,Ludwig J,et al. Drug eluting balloons as stand alone procedure for coronary bifurcational lesions:results of the randomized multicenter PEPCAD-BIF trial[J].Clin Res Cardiol,2016,105(7):613-621.
[10] Berland J,Lefèvre T,Brenot P,et al. DANUBIO-a new drug-eluting balloon for the treatment of side branches in bifurcation lesions:six-month angiographic followup results of the DEBSIDE trial[J]. Euro Intervention,2015,11(8):868-876.
[11] Piraino D,Carella M,Buccheri D,et al. Bifurcation lesions:Bioresorbable vascular scaffold and drug coated balloon,an efficacy association. Lessons from optimal coherence tomography[J]. Int J Cardiol,2016,212:92-93.
[2] López Mínguez JR,Nogales Asensio JM,Doncel Vecino LJ,et al. A prospective randomised study of the paclitaxel-coated balloon catheter in bifurcated coronary lesions(BABILON trial):24-month clinical and angiographic results[J].Euro Intervention,2014,10(1):50-57.
[3] Mathey DG,Wendig I,Boxberger M,et al. Treatment of bifurcation lesions with a drug-eluting balloon:the PEPCAD V(Paclitaxel Eluting PTCA Balloon in Coronary Artery Disease)trial[J]. Euro Intervention,2011,7(Suppl K):K61-K65.
[4] Herrador JA,Fernandez JC,Guzman M,et al. Drug-eluting vs. conventional balloon for side branch dilation in coronary bifurcations treated by provisional T stenting[J]. J Interv Cardiol,2013,26(5):454-462.
[5] Jim M,Lee MK,Fung RC,et al. Six month angiographic result of supplementary paclitaxel-eluting balloon deployment to treat side branch ostium narrowing(SARPEDON)[J]. Int J Cardiol,2015,187:594-597.
[6] Sgueglia GA,Todaro D,Bisciglia A,et al. Kissing inflation is feasible with all second-generation drug-eluting balloons[J]. Cardiovasc Revasc Med,2011,12(5):280-285.
[7] Burzotta F,Brancati MF,Trani C,et al. Impact of drug-eluting balloon(preor post-)dilation on neointima formation in de novo lesions treated by bare-metal stent:the IN-PACT CORO trial[J]. Heart Vessels,2016,31(5):677-686.
[8] Schulz A,Hauschild T,Kleber FX. Treatment of coronary de novo bifurcation lesions with DCB only strategy[J]. Clin Res Cardiol,2014,103(6):451-456.
[9] Kleber FX,Rittger H,Ludwig J,et al. Drug eluting balloons as stand alone procedure for coronary bifurcational lesions:results of the randomized multicenter PEPCAD-BIF trial[J].Clin Res Cardiol,2016,105(7):613-621.
[10] Berland J,Lefèvre T,Brenot P,et al. DANUBIO-a new drug-eluting balloon for the treatment of side branches in bifurcation lesions:six-month angiographic followup results of the DEBSIDE trial[J]. Euro Intervention,2015,11(8):868-876.
[11] Piraino D,Carella M,Buccheri D,et al. Bifurcation lesions:Bioresorbable vascular scaffold and drug coated balloon,an efficacy association. Lessons from optimal coherence tomography[J]. Int J Cardiol,2016,212:92-93.