2015与2016年琼中县中小学生血清维生素D水平对比分析
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摘要
目的了解海南省琼中县实施义务教育学生营养改善计划后血清维生素D水平的变化情况,评价营养改善计划实施效果,为制定改善中小学生维生素D缺乏的政策措施提供科学数据。方法采用分层整群随机抽样的方法对海南省琼中县2015～2016年实施学生营养改善计划的学校开展维生素D营养状况监测。共对1321名中小学生采集空腹静脉血,采用液相色谱-串联质谱法进行血清25-羟基维生素D[25-(OH)-VD]的检测。结果 2016年与2015年相比,中小学生血清25-(OH)-VD平均水平略有所下降,二者比较差异有统计学意义(P<0.05)。2015年女生维生素D不足率为8.61%,2016年女生维生素D不足率为18.37%,二者比较差异有统计学意义(P<0.05);2015年男生维生素D不足率为6.53%,2016年男生维生素D不足率为7.47%,二者比较差异无统计学意义(P>0.05)。结论海南省琼中县中小学生血清维生素D无缺乏,不足率低于国家平均水平,但2016年维生素D水平较2015年有所下降。
Objective To understand the changes of serum vitamin D levels after implementing the nutrition improvement program for compulsory education students in Qiongzhong county, Hainan province,and evaluate the effectiveness of the nutrition improvement program, and provide scientific data for the development of policy measures to improve vitamin D deficiency in primary and middle school students. Methods The nutritional status of vitamin D was monitored in schools which implementing the nutrition improvement program in Qiongzhong county of Hainan province by stratified random cluster sampling from 2015 to 2016. A total of 1321 primary and middle school students' fasting venous blood were collected. The serum 25-(OH)-VD was detected by liquid chromatography-tandem mass spectrometry.Results Compared with 2015,the average level of serum 25-(OH)-VD in primary and middle school students decreased significantly in 2016(P<0. 05). The vitamin D deficiency rates of girls were 8.61% and 18.27% in 2015 and 2016,there were significantly differences between two years(P<0. 05). The male vitamin D deficiency rates were 6. 53% and 7. 47%in 2015 and 2016,there were no significantly differences between two years(P>0. 05). Conclusion There is no shortage of serum vitamin D in primary and middle school students in Qiongzhong county, Hainan province. The deficiency rate is lower than the national average. However, the level of vitamin D in 2016 is lower than that in 2015.
Objective To understand the changes of serum vitamin D levels after implementing the nutrition improvement program for compulsory education students in Qiongzhong county, Hainan province,and evaluate the effectiveness of the nutrition improvement program, and provide scientific data for the development of policy measures to improve vitamin D deficiency in primary and middle school students. Methods The nutritional status of vitamin D was monitored in schools which implementing the nutrition improvement program in Qiongzhong county of Hainan province by stratified random cluster sampling from 2015 to 2016. A total of 1321 primary and middle school students' fasting venous blood were collected. The serum 25-(OH)-VD was detected by liquid chromatography-tandem mass spectrometry.Results Compared with 2015,the average level of serum 25-(OH)-VD in primary and middle school students decreased significantly in 2016(P<0. 05). The vitamin D deficiency rates of girls were 8.61% and 18.27% in 2015 and 2016,there were significantly differences between two years(P<0. 05). The male vitamin D deficiency rates were 6. 53% and 7. 47%in 2015 and 2016,there were no significantly differences between two years(P>0. 05). Conclusion There is no shortage of serum vitamin D in primary and middle school students in Qiongzhong county, Hainan province. The deficiency rate is lower than the national average. However, the level of vitamin D in 2016 is lower than that in 2015.
引文
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[12]李莺,马嘉子.1103名儿童维生素D营养状况的临床分析[J].中国卫生检验杂志,2017,27(5):672-673
[13]石鹏,王志,巴蕾.北京市朝阳区中小学生维生素D营养状况[J].职业与健康,2016,32(19):2694-2696
[14]宋淑军,贾海英,刘俊丽,等.季节对维生素D水平的影响[J].中国骨质疏松杂志,2014,20(8):900-903
[15]段杰,诺桑,吴玄峰,等.西藏大学学生维生素D营养状况分析[J].安徽预防医学杂志,2018,24(3):201-203
[2]Munns CF,Simm PJ,Rodda CP,et al.Incidence of vitamin D deficiency rickets among Australian chidren:an Australian Paediatric Surveillance Unit study[J].Med J Aust,2012,196(7):466-468
[3]Ward LM,Gaboury I,Ladhani M,et al.Vitamin D-deficiency rickets among children in Canada[J].CMAJ,2007,177(2);161-166
[4]Mansbach JM,Ginde AA,Canargo CA.Serum 25-Hydroxyvitamin D levels among US children aged 1 to 11years:do children need vitamin D?[J].Pediatrics,2009,124(5):1404-1410
[5]莫丽亚,黄彩芝,邓永超,等.湖南地区少年儿童维生素D营养状况分析[J].中国妇幼保健,2012,27(31):4926-4928
[6]张倩,赵静,张环美,等.北京市郊区儿童维生素D营养状况与骨量的关[J].中国预防医学杂志,2010,11(8):773-777
[7]中华人民共和国国务院办公厅.国务院办公厅关于实施农村义务教育学生营养改善计划的意见[EB/OL].2011-11-23.http://law.foodmate.net/show-175448.html
[8]张倩,甘倩,陈竞,等.学生营养改善计划地区2013年度学生维生素D营养状况[J].中国学校卫生,2016,37(5):664-666
[9]公维一,张之晗,周美琪,等.石家庄贫困地区学龄儿童秋季维生素D营养状况评价[J].卫生研究,2018,47(3):487-490
[10]史瑞金,陈丽珠,肖立波,等.海南省黎族地区中小学生营养知识态度行为分析[J].中国学校卫校,2012,33(4):457-458
[11]张杰,高艳军,赵耀,等.北京市密云区576名中小学生维生素D营养水平分析[J].职业与健康,2016,32(14):1993-1996
[12]李莺,马嘉子.1103名儿童维生素D营养状况的临床分析[J].中国卫生检验杂志,2017,27(5):672-673
[13]石鹏,王志,巴蕾.北京市朝阳区中小学生维生素D营养状况[J].职业与健康,2016,32(19):2694-2696
[14]宋淑军,贾海英,刘俊丽,等.季节对维生素D水平的影响[J].中国骨质疏松杂志,2014,20(8):900-903
[15]段杰,诺桑,吴玄峰,等.西藏大学学生维生素D营养状况分析[J].安徽预防医学杂志,2018,24(3):201-203