摘要
目的探讨颅内肿瘤患者的MRI影像学特征与预后的相关性。方法采用回顾性调查研究方法,选取颅内肿瘤患者52例作为颅内肿瘤组,选择同期进行体检的健康人52例作为对照组,记录2组的MRI影像学特征,颅内肿瘤患者在治疗后3个月进行预后认知功能判定与相关性分析。结果颅内肿瘤组与对照组的MoCA评分分别为(21.24±4.28)分和(28.11±1.98)分,颅内肿瘤组低于对照组(P <0.05)。颅内肿瘤组的脑白质疏松1级、2级、3级、4级患者分别为12例、14例、16例与10例,对照组分别为46例、5例、1例与0例,对比差异有统计学意义(P <0.05)。在颅内肿瘤组中,MRI显示瘤内血管流空、瘤周水肿、瘤内出血、囊变坏死所占比例分别为88.5%、65.4%、84.6%、76.9%。Pearson相关分析结果显示MoCA评分与MRI脑白质疏松分级呈现明显正相关性(P <0.05),也与瘤内血管流空、瘤周水肿、瘤内出血、囊变坏死呈现明显负相关性(P <0.05)。结论颅内肿瘤患者在预后存在明显的认知障碍,MRI影像学特征主要表现为脑白质疏松异常、瘤内血管流空、瘤周水肿,且MRI影像学特征与预后认知障碍存在明显相关性。
Objective To investigate the correlation between MRI imaging features and prognosis in patients with intracranial tumors.Methods Used a retrospective study,52 cases of patients with intracranial tumor were selected as intracranial tumor group,and the other 52 healthy people for medical examination were selected as the control group,recorded the MRI imaging features,3 months after treatment,the prognosis of cognitive function were given determination and correlation analysis.Results The MoCA scores in the intracranial tumor group and the control group were( 21.24 ± 4.28) points and( 28.11 ± 1.98)points,respectively,and the intracranial tumor group was lower than that of the control group( P < 0.05).There were 12 patients,14 patients,16 patients and 10 patients of WMLs grade 1,2,3 and 4 in the intracranial tumor group,so that were 10 were 46 patients,5 patients,1 patients and 0 patients respectively in the control group,and compared the difference were significant( P <0.05).In the intracranial tumor group,MRI showed intratumoral vascular flow,peritumoral edema,intratumoral hemorrhage,cystic necrosis accounted for 88.5%,65.4%,84.6%,76.9%; Pearson correlation analysis showed that MoCA score and WMLs grade were showed significant positive correlation( P < 0.05),and were significant positive correlation to the MRI intratumoral vascular flow,peritumoral edema,intratumoral hemorrhage,cystic necrosis.Conclusion There are obvious cognitive impairment in patients with intracranial tumors in the prognosis,MRI imaging showed WMLsabnormalities,intratumoral vascular flow,peritumoral edema,and the MRI imaging features are significantly related to the prognosis of cognitive impairment.
引文
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