全基因组关联分析在油菜遗传育种中的应用和研究进展
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摘要
全基因组关联分析(genome-wide association studies,GWAS)是近几年发展起来的解析作物表型多样性遗传基础的有效分析手段。GWAS以连锁不平衡为基础鉴定某一作物群体内农艺性状即表型数据与全基因组基因型数据或候选基因间的具体关系,具有高通量(即在全基因组范围有效检测性状与基因位点的关联性)、精度高和花费时间少等显著优点,其在作物遗传育种中的作用日益凸显。本综述在系统介绍GWAS这种方法的基础上,详尽总结了其在油菜遗传育种中的应用和研究进展、存在的潜在问题及解决途径,以期为进一步利用GWAS进行油菜各种性状遗传基础的研究提供依据和参考。
Genome-wide association studies(GWAS) is an effective analysis method for analyzing genetic basis of crop phenotypic diversity which has been developed in recent years.Based on linkage disequilibrium,GWAS identifies agronomic traits in a crop population,that is,the specific relationship between phenotypic data and genome-wide data or candidate genes,which has significant advantages in high-throughput(that is the correlation between the whole genome-wide detection of traits and gene loci),high precision and less time,and its role in crop genetics and breeding has become increasingly prominent.Based on the systematic introduction of GWAS,this review summarized its application and research progress in rapeseed and its potential problems and solutions,hoping to provide the basis and reference for further research on the genetic basis of various characters of rape by using GWAS.
Genome-wide association studies(GWAS) is an effective analysis method for analyzing genetic basis of crop phenotypic diversity which has been developed in recent years.Based on linkage disequilibrium,GWAS identifies agronomic traits in a crop population,that is,the specific relationship between phenotypic data and genome-wide data or candidate genes,which has significant advantages in high-throughput(that is the correlation between the whole genome-wide detection of traits and gene loci),high precision and less time,and its role in crop genetics and breeding has become increasingly prominent.Based on the systematic introduction of GWAS,this review summarized its application and research progress in rapeseed and its potential problems and solutions,hoping to provide the basis and reference for further research on the genetic basis of various characters of rape by using GWAS.
引文
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