中医治疗反流性食管炎研究进展
摘要
反流性食管炎是一种全球范围内的常见疾病,患者比例逐年增加,西医治疗多抑酸护胃、促胃动力,有一定疗效,但副作用大、易反复、价格昂贵。近年来,中医治疗本病因具有疗效显著起效机制多重、治疗方法多样、复发率低、副作用小、价格优惠等优势而备受欢迎。现就近年来中医治疗反流性食管炎的经验研究综述如下。
引文
[1]Yamasaki T,Hemond C,Eisa M,et al.The Changing Epidemiology of Gastroesophageal Reflux Disease:Are Patients Getting Younger?[J].Journal of Neurogastroenterology and Motility,2018,24:559-569.
[2]Jung HK.Epidemiology of gastroesophageal reflux disea inAsia:a systematic review[J].Neurogastroenterol Motil,2011,17(1):14-27.
[3]Katz PO,Gerson LB,Vela MF.Guidelines for the diagnosis and management of gastroesophageal reflux disease[J].Am J Gastroenterol,2013,108(3):308-328.
[4]Fass R,Sifrim D.Management of heartburn not responding to proton pump inhibitors[J].Gut,2009,58(2):295309.
[5]El-Serag HB,Sweet S,Winchester CC,et al.Update on the epidemiology of gastro-oesophageal reflux disease:a systematic review[J].Gut,2013,63(6):871-80.
[6]樊敏.柴胡温胆汤合乌贝散治疗反流性食管炎肝胃郁热证的临床疗效观察[D].新疆医科大学,2018.
[7]王雪利.旋覆代赭汤加减治疗反流性食管炎临床观察[J].光明中医,2018,33(23):3504-3505+3519.
[8]曹翠纳,张北平,赵喜颖.半夏泻心汤对反流性食管炎患者临床疗效及焦虑、睡眠质量的影响[J].广州中医药大学学报,2018,35(05):779-784.
[9]刘巧丽,韩惠杰,周萍,等.国医大师经验方清胃颗粒治疗难治性反流性食管炎的临床研究[J].世界中西医结合杂志,2018,13(09):1267-1270.
[10]李翠玉.中西医结合治疗反流性食管炎疗效观察[J].实用中医药杂志,2018,34(02):210-212.
[11]魏群,魏晏,魏明,等.奥瑞凝胶对反流性食管炎患者血清胃泌素水平的影响[J].中医学报,2018,33(11):2218-2221.
[12]潘丹烨.食管宁联合西药治疗反流性食管炎食管源性咳嗽的临床观察[D].湖北中医药大学,2018.
[13]于彦.范春琦治疗反流性食管炎用药规律的研究[J].世界中医药,2016,11(02):262-265.
[14]刘宏,叶柏.叶柏教授治疗反流性食管炎经验辑要[J].中国中医急症,2016,25(05):831-833.
[15]周春燕颜勤.徐学义教授治疗反流性食管炎临床经验[J].现代中医药,2016,36(03):7-9.
[16]苏联军,周慎.欧阳锜从郁痰化热论治反流性食管炎经验[J].内蒙古中医药,2017,36(09):51.
[17]闫秀丽,朱生樑,程艳梅,等.中医辨证治疗胃食管反流病疗效观察[J].辽宁中医杂志,2018,45(05):991-994.
[18]杨玲.加味四逆散联合针灸疗法在反流性食管炎中的应用效果分析[J].中医药指南,2018,16(24):178-179.
[19]廖毅敏.加味四逆散联合针灸疗法在反流性食管炎中的应用[J].中医药信息,2016,33(2):92-94
[20]李良玉,周兰利.中医综合疗法治疗反流性食管炎疗效观察[J].光明中医,2017,32(12):1693-1695.
[21]郭阳青.针药并用治疗肝胃郁热型反流性食管炎临床观察[J].上海针灸杂志,2018,37(10):1126-1131.
[22]史海霞,李依洁,王燕丽,等.辛开苦降法对反流性食管炎模型大鼠食道下段组织iNOS蛋白表达的影响[J].世界中西医结合杂志,2016,11(12):1672-1675+1693.
[23]尚莹莹,李黎,黄天生,等.疏肝和胃复方对反流性食管炎大鼠胃肠激素影响的实验研究[J].辽宁中医杂志,2017,44(11):2421-2422+2464.
[24]黄棪,徐明英,夏雪皎,等.旋覆代赭汤对胆碱能抗炎通路相关RE大鼠炎症因子的影响[J].天津中医药大学学报,2018,37(05):386-389.
[25]马英歌,张艳丽,张晓楠,等.柴芍六君汤联合左金丸治疗肝胃郁热型反流性食管炎临床研究[J].新中医,2019(01):78-82.
[26]Souza,R.F.,Bayeh,L.,Spechler,S.J.,et al.A new paradigm for GERDpathogenesis.Not acid injury,but cytokine-mediated inflammation driven by HIF-2α:a potential role for targeting HIF-2αto prevent and treat reflux esophagitis[J].Current Opinion in Pharmacology,2017,37,93-99.
[27]Winkelsett L;Malfertheiner P;Wex T;Kandulski A.Mucosal Two-Step Pathogenesis in Gastroesophageal Reflux Disease:Repeated Weakly Acidic Stimulation and Activation of Protease-Activated Receptor-2 on Mucosal Interleukin-8 Secretion[J].DIGESTION,2018,98(1):19-25.
[2]Jung HK.Epidemiology of gastroesophageal reflux disea inAsia:a systematic review[J].Neurogastroenterol Motil,2011,17(1):14-27.
[3]Katz PO,Gerson LB,Vela MF.Guidelines for the diagnosis and management of gastroesophageal reflux disease[J].Am J Gastroenterol,2013,108(3):308-328.
[4]Fass R,Sifrim D.Management of heartburn not responding to proton pump inhibitors[J].Gut,2009,58(2):295309.
[5]El-Serag HB,Sweet S,Winchester CC,et al.Update on the epidemiology of gastro-oesophageal reflux disease:a systematic review[J].Gut,2013,63(6):871-80.
[6]樊敏.柴胡温胆汤合乌贝散治疗反流性食管炎肝胃郁热证的临床疗效观察[D].新疆医科大学,2018.
[7]王雪利.旋覆代赭汤加减治疗反流性食管炎临床观察[J].光明中医,2018,33(23):3504-3505+3519.
[8]曹翠纳,张北平,赵喜颖.半夏泻心汤对反流性食管炎患者临床疗效及焦虑、睡眠质量的影响[J].广州中医药大学学报,2018,35(05):779-784.
[9]刘巧丽,韩惠杰,周萍,等.国医大师经验方清胃颗粒治疗难治性反流性食管炎的临床研究[J].世界中西医结合杂志,2018,13(09):1267-1270.
[10]李翠玉.中西医结合治疗反流性食管炎疗效观察[J].实用中医药杂志,2018,34(02):210-212.
[11]魏群,魏晏,魏明,等.奥瑞凝胶对反流性食管炎患者血清胃泌素水平的影响[J].中医学报,2018,33(11):2218-2221.
[12]潘丹烨.食管宁联合西药治疗反流性食管炎食管源性咳嗽的临床观察[D].湖北中医药大学,2018.
[13]于彦.范春琦治疗反流性食管炎用药规律的研究[J].世界中医药,2016,11(02):262-265.
[14]刘宏,叶柏.叶柏教授治疗反流性食管炎经验辑要[J].中国中医急症,2016,25(05):831-833.
[15]周春燕颜勤.徐学义教授治疗反流性食管炎临床经验[J].现代中医药,2016,36(03):7-9.
[16]苏联军,周慎.欧阳锜从郁痰化热论治反流性食管炎经验[J].内蒙古中医药,2017,36(09):51.
[17]闫秀丽,朱生樑,程艳梅,等.中医辨证治疗胃食管反流病疗效观察[J].辽宁中医杂志,2018,45(05):991-994.
[18]杨玲.加味四逆散联合针灸疗法在反流性食管炎中的应用效果分析[J].中医药指南,2018,16(24):178-179.
[19]廖毅敏.加味四逆散联合针灸疗法在反流性食管炎中的应用[J].中医药信息,2016,33(2):92-94
[20]李良玉,周兰利.中医综合疗法治疗反流性食管炎疗效观察[J].光明中医,2017,32(12):1693-1695.
[21]郭阳青.针药并用治疗肝胃郁热型反流性食管炎临床观察[J].上海针灸杂志,2018,37(10):1126-1131.
[22]史海霞,李依洁,王燕丽,等.辛开苦降法对反流性食管炎模型大鼠食道下段组织iNOS蛋白表达的影响[J].世界中西医结合杂志,2016,11(12):1672-1675+1693.
[23]尚莹莹,李黎,黄天生,等.疏肝和胃复方对反流性食管炎大鼠胃肠激素影响的实验研究[J].辽宁中医杂志,2017,44(11):2421-2422+2464.
[24]黄棪,徐明英,夏雪皎,等.旋覆代赭汤对胆碱能抗炎通路相关RE大鼠炎症因子的影响[J].天津中医药大学学报,2018,37(05):386-389.
[25]马英歌,张艳丽,张晓楠,等.柴芍六君汤联合左金丸治疗肝胃郁热型反流性食管炎临床研究[J].新中医,2019(01):78-82.
[26]Souza,R.F.,Bayeh,L.,Spechler,S.J.,et al.A new paradigm for GERDpathogenesis.Not acid injury,but cytokine-mediated inflammation driven by HIF-2α:a potential role for targeting HIF-2αto prevent and treat reflux esophagitis[J].Current Opinion in Pharmacology,2017,37,93-99.
[27]Winkelsett L;Malfertheiner P;Wex T;Kandulski A.Mucosal Two-Step Pathogenesis in Gastroesophageal Reflux Disease:Repeated Weakly Acidic Stimulation and Activation of Protease-Activated Receptor-2 on Mucosal Interleukin-8 Secretion[J].DIGESTION,2018,98(1):19-25.