中医药治疗溃疡性结肠炎研究进展
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摘要
目前,溃疡性结肠炎发病机制尚不明确,是临床的难治疾病之一。中医药治疗溃疡性结肠炎疗效确切,副作用少,复发率低,显示出了独特优势,本文从病因病机、辨证分型论治、经验方专用、中药保留灌肠、综合治疗方法等方面概述近5年中医药治疗溃疡性结肠炎的研究进展,以期为本病的治疗提供新的思路与方法。
At present,the pathogenesis of ulcerative colitis( UC) is still unclear and it is one of the clinical refractory diseases.Chinese medicine treatment of ulcerative colitis is effective,with fewer side effects and low recurrence rate,showing a unique advantage. This article will outline the pathogenesis,syndrome differentiation,treatment experience,traditional Chinese medicine retention enema,comprehensive treatment methods,etc. In the past five years,the research progress of traditional Chinese medicine in the treatment of ulcerative colitis has provided new ideas and methods for the treatment of this disease.
At present,the pathogenesis of ulcerative colitis( UC) is still unclear and it is one of the clinical refractory diseases.Chinese medicine treatment of ulcerative colitis is effective,with fewer side effects and low recurrence rate,showing a unique advantage. This article will outline the pathogenesis,syndrome differentiation,treatment experience,traditional Chinese medicine retention enema,comprehensive treatment methods,etc. In the past five years,the research progress of traditional Chinese medicine in the treatment of ulcerative colitis has provided new ideas and methods for the treatment of this disease.
引文
[1]Liu Z,Zhou K,Tian S,et al.Ulcerative colitis with Guillain-Barrésyndrome:A case report[J].Medicine(Baltimore),2018,97(25):e11013.
[2]Ryuichi Yamamoto,Kouhei Muroi,Hiromasa Imaishi.Serum derived from ulcerative colitis mouse changes the metabolism of the fluorescent substrate by P450 depending on the degree of disease progression[J].Chemico-Biological Interaction.2018,290(5):88-89.
[3]林赛争,蔡建庭,陈焰,等.难治性炎症性肠病患者艰难梭状芽胞杆菌感染流行病学及临床特征[J].中华医院感染学杂志,2017,27(10):2173-2176.
[4]初祯.106例溃疡性结肠炎临床病理学特征分析[J].中国疗养医学,2018,27(7):752-755.
[5]马普伟,周福生.周福生名老中医辨证论治溃疡性结肠炎经验[J].中医临床研究,2017,9(28):49-50.
[6]徐艺.单兆伟论治缓解期溃疡性结肠炎的经验总结[J].辽宁中医杂志,2015,42(12):2311-2312.
[7]蔡晓霖,吴志平,李英莲,等.郭为汀主任医师治疗溃疡性结肠炎经验撷菁[J].新中医,2015,47(10):17-18.
[8]朱磊,沈洪,顾培青,等.沈洪教授治疗溃疡性结肠炎的经验探析[J].中华中医药杂志,2015,30(7):2381-2383.
[9]张红梅,李姿慧,蔡荣林,等.浅析溃疡性结肠炎的“湿”性病因[J].江西中医药大学学报,2017,29(2):1-2,13.
[10]杨静.健脾疏肝法维持溃疡性结肠炎肝郁脾虚证缓解疗效评价研究[D].南京:南京中医药大学,2018.
[11]白海燕,毛宇湘.从浊毒论治溃疡性结肠炎[J].环球中医药,2016,9(11):1296-1298.
[12]徐道君,张景洲,李济同.从中医学络病学及肝郁理论认识溃疡性结肠炎[J].临床医药文献电子杂志,2014,1(14):2889.
[13]李颖,吕章明,李桃桃,等.从“瘀阻肠角”论治活动期溃疡性结肠炎的探析[J].中国中医急症,2016,25(4):640-641,652.
[14]徐发莹.徐珊治疗溃疡性结肠炎经验[J].中医杂志,2015,56(3):195-197.
[15]朱卫,高亚,王爱华,等.王爱华教授辨治溃疡性结肠炎经验[J].湖南中医药大学学报,2017,37(1):48-51.
[16]曲歌,施丽婕,杨强.杨强治疗溃疡性结肠炎临床经验[J].亚太传统医药,2017,13(6):92-93.
[17]陈红宇,沈洪.沈洪教授运用灌肠方治疗溃疡性结肠炎经验[J].浙江中医药大学学报,2017,41(1):66-68.
[18]李毅,刘艳,刘力,等.溃疡性结肠炎症状学聚类研究[J].现代中西医结合杂志,2016,25(10):1027-1029,1043.
[19]周宇倩,陈忠义.80例溃疡性结肠炎的中医证型特点分析[J].辽宁中医杂志,2017,44(12):2569-2571.
[20]宋晓红.中药辨证治疗慢性溃疡性结肠炎120例临床观察[J].当代医学,2017,23(2):71-72.
[21]李新巧.辨证分型、灌肠联合中药治疗溃疡性结肠炎45例临床观察[J].实用中医内科杂志,2014,28(10):35-36.
[22]毛堂友,程佳伟,魏仕兵,等.清肠温中方治疗溃疡性结肠炎84例[J].环球中医药,2016.9(4):479-481.
[23]贾宁.乌梅汤治疗溃疡性结肠炎40例[J].河南中医,2016,36(1):26-27.
[24]张海燕.半夏泻心汤治疗溃疡性结肠炎40例临床研究[J].亚太传统医药,2016,12(2):109-110.
[25]颜丽花,王小娟.痛泻要方加减治疗慢性溃疡性结肠炎34例疗效观察[J].湖南中医杂志,2016,32(6):55-56.
[26]丁永福.健脾清肠汤治疗脾虚湿热型溃疡性结肠炎40例[J].西部中医药,2018,31(2):88-90.
[27]李广星,赵迎.治溃方治疗溃疡性结肠炎肝郁脾虚证30例[J].河南中医,2016,36(6):1046-1048.
[28]张菁,曹学敏.中药灌肠液治疗慢性溃疡性结肠炎36例[J].河南中医,2016,36(7):1193-1195.
[29]李兵剑.乌梅丸保留灌肠治疗远端型溃疡性结肠炎24例临床观察[J].甘肃中医药大学学报,2018,35(2):53-57.
[30]王胜文.中医综合疗法治疗溃疡性结肠炎42例[J].河南中医,2016,36(4):643-645.
[31]席玉红,党中勤,李严生,等.中医综合疗法联合辨证施护治疗溃疡性结肠炎60例观察[J].中医药导报,2014,20(5):110-112.
[32]梁永生,张春艳,李敬伟,等.中医综合疗法(中药方口服、药物灌肠、针灸)与西医治疗溃疡性结肠炎的临床疗效比较[J].医疗装备,2016,29(2):119-120.
[33]姚德荣.分析中医综合疗法治疗48例溃疡性结肠炎临床疗效[J].中国继续医学教育,2015,7(5):243-244.
[34]Wen Y,Shi L,Li J,et al.Acupuncture combined with acupoint catgut embedding sequential therapy for mild and moderate ulcerative colitis[J].Zhongguo Zhen Jiu,2018,38(4):353-357.
[35]刘刚,周莉,熊国卫,等.中西医结合治疗溃疡性结肠炎32例[J].中医临床研究,2017,9(22):76-78.
[36]付怀成.中西医结合治疗溃疡性结肠炎41例临床观察[J].江苏中医药,2016,48(3):41-42.
[37]袁联华.中西医结合治疗溃疡性结肠炎疗效观察[J].实用中医药杂志,2018,34(6):694-695.
[38]刘丰阁.中西医结合治疗溃疡性结肠炎临床观察[J].实用中医药杂志,2018,34(3):326-327.
[39]崔景怡,金玲,李慕然,等.促愈祛毒方内服灌肠辅助治疗活动期溃疡性结肠炎疗效及对血清炎性细胞因子、TGF-β、MMP-1水平的影响[J].中国中医急症,2018,27(7):1263-1265.
[40]Wang HG,Liu SP,Ma TH,et al.Fecal microbiota transplantation treatment for refractory ulcerative colitis with allergy to 5-aminosalicylic acid:A case report[J].Medicine(Baltimore),2018,97(19):e0675.
[2]Ryuichi Yamamoto,Kouhei Muroi,Hiromasa Imaishi.Serum derived from ulcerative colitis mouse changes the metabolism of the fluorescent substrate by P450 depending on the degree of disease progression[J].Chemico-Biological Interaction.2018,290(5):88-89.
[3]林赛争,蔡建庭,陈焰,等.难治性炎症性肠病患者艰难梭状芽胞杆菌感染流行病学及临床特征[J].中华医院感染学杂志,2017,27(10):2173-2176.
[4]初祯.106例溃疡性结肠炎临床病理学特征分析[J].中国疗养医学,2018,27(7):752-755.
[5]马普伟,周福生.周福生名老中医辨证论治溃疡性结肠炎经验[J].中医临床研究,2017,9(28):49-50.
[6]徐艺.单兆伟论治缓解期溃疡性结肠炎的经验总结[J].辽宁中医杂志,2015,42(12):2311-2312.
[7]蔡晓霖,吴志平,李英莲,等.郭为汀主任医师治疗溃疡性结肠炎经验撷菁[J].新中医,2015,47(10):17-18.
[8]朱磊,沈洪,顾培青,等.沈洪教授治疗溃疡性结肠炎的经验探析[J].中华中医药杂志,2015,30(7):2381-2383.
[9]张红梅,李姿慧,蔡荣林,等.浅析溃疡性结肠炎的“湿”性病因[J].江西中医药大学学报,2017,29(2):1-2,13.
[10]杨静.健脾疏肝法维持溃疡性结肠炎肝郁脾虚证缓解疗效评价研究[D].南京:南京中医药大学,2018.
[11]白海燕,毛宇湘.从浊毒论治溃疡性结肠炎[J].环球中医药,2016,9(11):1296-1298.
[12]徐道君,张景洲,李济同.从中医学络病学及肝郁理论认识溃疡性结肠炎[J].临床医药文献电子杂志,2014,1(14):2889.
[13]李颖,吕章明,李桃桃,等.从“瘀阻肠角”论治活动期溃疡性结肠炎的探析[J].中国中医急症,2016,25(4):640-641,652.
[14]徐发莹.徐珊治疗溃疡性结肠炎经验[J].中医杂志,2015,56(3):195-197.
[15]朱卫,高亚,王爱华,等.王爱华教授辨治溃疡性结肠炎经验[J].湖南中医药大学学报,2017,37(1):48-51.
[16]曲歌,施丽婕,杨强.杨强治疗溃疡性结肠炎临床经验[J].亚太传统医药,2017,13(6):92-93.
[17]陈红宇,沈洪.沈洪教授运用灌肠方治疗溃疡性结肠炎经验[J].浙江中医药大学学报,2017,41(1):66-68.
[18]李毅,刘艳,刘力,等.溃疡性结肠炎症状学聚类研究[J].现代中西医结合杂志,2016,25(10):1027-1029,1043.
[19]周宇倩,陈忠义.80例溃疡性结肠炎的中医证型特点分析[J].辽宁中医杂志,2017,44(12):2569-2571.
[20]宋晓红.中药辨证治疗慢性溃疡性结肠炎120例临床观察[J].当代医学,2017,23(2):71-72.
[21]李新巧.辨证分型、灌肠联合中药治疗溃疡性结肠炎45例临床观察[J].实用中医内科杂志,2014,28(10):35-36.
[22]毛堂友,程佳伟,魏仕兵,等.清肠温中方治疗溃疡性结肠炎84例[J].环球中医药,2016.9(4):479-481.
[23]贾宁.乌梅汤治疗溃疡性结肠炎40例[J].河南中医,2016,36(1):26-27.
[24]张海燕.半夏泻心汤治疗溃疡性结肠炎40例临床研究[J].亚太传统医药,2016,12(2):109-110.
[25]颜丽花,王小娟.痛泻要方加减治疗慢性溃疡性结肠炎34例疗效观察[J].湖南中医杂志,2016,32(6):55-56.
[26]丁永福.健脾清肠汤治疗脾虚湿热型溃疡性结肠炎40例[J].西部中医药,2018,31(2):88-90.
[27]李广星,赵迎.治溃方治疗溃疡性结肠炎肝郁脾虚证30例[J].河南中医,2016,36(6):1046-1048.
[28]张菁,曹学敏.中药灌肠液治疗慢性溃疡性结肠炎36例[J].河南中医,2016,36(7):1193-1195.
[29]李兵剑.乌梅丸保留灌肠治疗远端型溃疡性结肠炎24例临床观察[J].甘肃中医药大学学报,2018,35(2):53-57.
[30]王胜文.中医综合疗法治疗溃疡性结肠炎42例[J].河南中医,2016,36(4):643-645.
[31]席玉红,党中勤,李严生,等.中医综合疗法联合辨证施护治疗溃疡性结肠炎60例观察[J].中医药导报,2014,20(5):110-112.
[32]梁永生,张春艳,李敬伟,等.中医综合疗法(中药方口服、药物灌肠、针灸)与西医治疗溃疡性结肠炎的临床疗效比较[J].医疗装备,2016,29(2):119-120.
[33]姚德荣.分析中医综合疗法治疗48例溃疡性结肠炎临床疗效[J].中国继续医学教育,2015,7(5):243-244.
[34]Wen Y,Shi L,Li J,et al.Acupuncture combined with acupoint catgut embedding sequential therapy for mild and moderate ulcerative colitis[J].Zhongguo Zhen Jiu,2018,38(4):353-357.
[35]刘刚,周莉,熊国卫,等.中西医结合治疗溃疡性结肠炎32例[J].中医临床研究,2017,9(22):76-78.
[36]付怀成.中西医结合治疗溃疡性结肠炎41例临床观察[J].江苏中医药,2016,48(3):41-42.
[37]袁联华.中西医结合治疗溃疡性结肠炎疗效观察[J].实用中医药杂志,2018,34(6):694-695.
[38]刘丰阁.中西医结合治疗溃疡性结肠炎临床观察[J].实用中医药杂志,2018,34(3):326-327.
[39]崔景怡,金玲,李慕然,等.促愈祛毒方内服灌肠辅助治疗活动期溃疡性结肠炎疗效及对血清炎性细胞因子、TGF-β、MMP-1水平的影响[J].中国中医急症,2018,27(7):1263-1265.
[40]Wang HG,Liu SP,Ma TH,et al.Fecal microbiota transplantation treatment for refractory ulcerative colitis with allergy to 5-aminosalicylic acid:A case report[J].Medicine(Baltimore),2018,97(19):e0675.