中药制剂对人工感染鸡大肠杆菌病疗效的研究
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摘要
为了考察中药制剂对人工感染鸡大肠杆菌病的治疗效果。以大肠杆菌标准菌株O_(78)、O_1、O_2三种混合大肠杆菌菌液肌肉注射感染15日龄海蓝褐蛋公鸡,之后口服不同剂量的中药制剂与氟苯尼考粉,观察试验鸡的临床症状、病理变化、病变发生率等,最终统计出试验鸡的死亡率和治愈率。采用Duncan法多重比较,结果各试验组鸡只死亡率均与感染对照组差异显著(P<0.05),而试验组之间差异不显著(P>0.05),中药高剂量组对感染鸡只治愈率与感染对照组鸡只自愈率差异显著(P<0.05),且近似于氟苯尼考粉组。因此,中药制剂可以作为有效控制和治疗鸡大肠杆菌病的途径之一。
The purpose of this study was to investigate the therapeutic effect of Chinese Herbal Medicines on Chicken Colibacillosis.The method used 3 mixed standard strains of E.coli solution O_(78),O_1,O_02 to infect 15 day-old of highland brown egg rooster by intramuscular injection,and then different doses of Chinese Herbal Medicines and florfenicol powder were given orally,And then the clinical symptoms,pathological changes,incidence of disease were observed,and mortality rate and cure rate were recorded.The results showed that,significant difference(P <0.05) was observed in mortality rate between trial group and infection control group,while there was no significant difference in the trialgroups(P > 0.05) The cure rate was significant difference(P < 0.05) between infected chickens and control group using high dose of Chinese herbal medicine,which was similar to florfenicol powder group.Therefore,it can be concluded that the Chinese Herbal Medicines can be used to effectively control and treat the chicken colibacillosis.
The purpose of this study was to investigate the therapeutic effect of Chinese Herbal Medicines on Chicken Colibacillosis.The method used 3 mixed standard strains of E.coli solution O_(78),O_1,O_02 to infect 15 day-old of highland brown egg rooster by intramuscular injection,and then different doses of Chinese Herbal Medicines and florfenicol powder were given orally,And then the clinical symptoms,pathological changes,incidence of disease were observed,and mortality rate and cure rate were recorded.The results showed that,significant difference(P <0.05) was observed in mortality rate between trial group and infection control group,while there was no significant difference in the trialgroups(P > 0.05) The cure rate was significant difference(P < 0.05) between infected chickens and control group using high dose of Chinese herbal medicine,which was similar to florfenicol powder group.Therefore,it can be concluded that the Chinese Herbal Medicines can be used to effectively control and treat the chicken colibacillosis.
引文
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[9]刘守怀.中药防治鸡传染病的临床应用及机理研究现状[J].中兽医学杂志,1992(2):45-47.
[2]叶裕香,韦丽金,张建华.仔猪黄白痢的综合防治[J].中兽医学杂志,2004(05):16-18.
[3]方芳,吕昭萍,王正文,等.山苍子油抗念珠菌的敏感性及作用机理的电镜研究[J].中华皮肤科杂志,2002,35(5):349-351.
[4]张文平,傅颖媛,谢小梅,等.肉桂醛抗曲霉菌作用机制研究[J].江西医学院学报,2003,43(6):10-14.
[5]韩冬,徐锡鸿.细菌黏附和中医药抗细菌黏附研究进展(J].辽宁中医杂志,1994,21(12):569-570.
[6]康梅,许秀成.三黄片对大肠杆菌耐药质粒消除作用的研究[J].华西药学杂志,1999,14(5):406-408.
[7]鞠洪涛,韩文瑜,王世若,等.大肠杆菌耐药基因定位及耐药质粒消除[J].中国兽医学报,2000,20(6):561-562.
[8]王桂英,武目胜,司振书.复方郁金散对鸡大肠杆菌病的临床疗效观察[J].山东畜牧兽医,2003,24(3):9-10.
[9]刘守怀.中药防治鸡传染病的临床应用及机理研究现状[J].中兽医学杂志,1992(2):45-47.