摘要
大蒜素是从新鲜大蒜中提取的挥发性油状物,为多种烯丙基有机硫化合物复合体,是大蒜中主要的有效生物学活性成分。具有多种生物学功能,降血脂、抗菌消炎、提高免疫力,预防心血管疾病等生理学作用。与传统药物相比大蒜素具有在人和动物体内残留量低,不易造成环境污染,来源广泛的优点,近期研究证实大蒜素还具有抗癌作用,对多种肿瘤细胞如肝癌、胃癌、结肠癌、肺癌等具有明显的抑制作用。本文就大蒜素的抗肿瘤作用及其机制的研究进展做一综述。
Allicin as a volatile oil content extracted from freshly garlic which is a complx includes a variety of allyl organosulfur components. One of the most biologically active ingredient of garlic. Allicin contents abundant of biological functions, lipid-lowering, anti-bacterial, alleviates inflammation, immune-enhancing, to prevent heart vascular disease and other physiological function.Compared with traditional chemical theropy, allicin is low residues in human and animals, non environmental pollution and has a broad resource. Recent study verify that allicin is able to obviously inhibite cancer cell proliferation, such as liver cancer, gastric cancer, colon carcinoma, lung cancer.Author briefly summarized recent research progress in the anti-tumor effect and mechanism of allicin.
引文
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