国医大师禤国维教授分期论治硬皮病经验
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摘要
总结归纳禤国维治疗硬皮病的临床经验,禤教授认为本病的发病机制为肝肾不足,气血两虚,寒凝血瘀,痹阻脉络而致肌肤失养,病性为本虚标实;肝肾阴虚、气血不足为本,寒凝血瘀为标;提出了滋补肝肾、益气补血、温阳散寒、活血通络的总治则。
This paper summarized the clinical treatment experience of XUAN Guo-wei in treating scleroderma. Professor XUAN considers that the basic pathogenesis is skin losing nourishing caused by deficiency of liver and kidney, deficiency of Qi and blood, cold coagulation and blood stasis and arthralgia venation. The nature of disease is deficiency in origin and excess in superficiality, and deficiency in origin is focused on deficiency of liver and kidney, deficiency of Qi and blood, while excess in superficiality is focused on cold coagulation and blood stasis; Professor XUAN put forward the principle that nourishing liver and kidney, supplementing Qi and enriching blood, warming Yang and dispersing cold, promoting blood circulation and dredging collaterals.
This paper summarized the clinical treatment experience of XUAN Guo-wei in treating scleroderma. Professor XUAN considers that the basic pathogenesis is skin losing nourishing caused by deficiency of liver and kidney, deficiency of Qi and blood, cold coagulation and blood stasis and arthralgia venation. The nature of disease is deficiency in origin and excess in superficiality, and deficiency in origin is focused on deficiency of liver and kidney, deficiency of Qi and blood, while excess in superficiality is focused on cold coagulation and blood stasis; Professor XUAN put forward the principle that nourishing liver and kidney, supplementing Qi and enriching blood, warming Yang and dispersing cold, promoting blood circulation and dredging collaterals.
引文
[1]Prinz J C,Kutasi Z,Weisenseel P,et al."Borrelia-associated early-onset morphea":a particular type of scleroderma in childhood andadolescence with high titer antinuclear antibodies?Results of a co-hort analysis and presentation of three cases[J].J Am Acad Derma-tol,2009(60):248-255.
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[3]Lembo S,Megna M,Balato A,et al."Cowboy's belt with revolver"scleroderma caused by vitamin K1 injections[J].G Ital DermatolVenereol,2012(147):203-205.
[4]Mosterd K,Winnepenninckx V,Vermeulen A,et al.Morphea follow-ing surgery and radiotherapy:an evolving problem[J].J Eur AcadDermatol Venereol,2009(23):1099-1101.
[5]陈卫,杨蓉娅.硬皮病的治疗现状与展望[J].实用皮肤病学杂志,2015,8(5):367-370.
[6]黄帝内经·素问[M].田代华,整理.北京:人民卫生出版社,2005:85.
[7]巢元方.诸病源候论[M].北京:人民卫生出版社,1956:5.
[8]杨克勤.张怀亮教授治疗硬皮病经验[J].中医研究,2013,26(7):55-56.
[9]吴德鸿,李正富,范永升.范永升教授治疗硬皮病经验[J].中华中医药杂志,2015,30(6):1990-1992.
[10]王俊志,王喜,吴迪.白郡符老中医治疗硬皮病经验[J].光明中医,2016,31(7):929-930.
[11]李颖,周平安.周平安教授治疗硬皮病经验浅析[J].新中医,2012,44(3):154-156.
[12]柳丽,张洪泉.丹参活性成分的现代中药药理研究进展[J].中国野生植物资源,2003,22(6):1-4.
[13]邓家刚,梁宁,周程艳.鸡血藤药效及作用机理研究进展[J].广西中医药,2006,29(6):1-3.
[14]陈从显,徐爱钰,许勇,等.鸡血藤总黄酮对小鼠急性肝损伤的保护作用[J].滨州医学院学报,2012,35(3):189-191.
[15]曾粤.徐长卿的研究进展[J].内蒙古中医药,2012,31(11):125-126.
[16]杨璐.积雪草苷药理作用及其机制的研究进展[J].中华中医药学刊,2008,26(1):215-218.
[17]杨玉琴,丁永辉,夏玉凤.积雪草活性成分的分析方法及药理作用研究进展[J].中国野生植物资源,2010,29(3):6-9.
[18]吕超田,姚向阳,孙程.灵芝主要活性药物及其药理作用研究[J].安徽农业通报,2011,17(1):50-52.
[19]金培志,张建勇,李林.滋阴狼疮胶囊在系统性红斑狼疮激素撤减中的临床应用研究[J].河南中医学院学报,2006,21(4):21-22,24.
[20]查良伦,沈自尹,施凤英,等.补肾中药拮抗皮质激素所致副反应的实验观察[J].上海中医药杂志,1990,24(2):1-3.
[21]任志萍.黄芪现代药理学研究进展[J].中国民族民间医药,2010,19(3):35.
[22]黄伏顺.太子参的功效特点[J].江苏中医,1993,14(4):29-30.
[23]刘东,韩邦兴,姚厚军,等.太子参化学成分研究进展[J].中国民族民间医药,2014,23(16):18-20.
[2]Takahashi T,Asano Y,Ichimura Y,et al.A case of taxane-inducedscleroderma:a different expression profile of Fli1 proteins in dermalfibroblasts and microvascular endothelial cells compared with system-ic sclerosis[J].Br JDermatol,2011(164):1393-1395.
[3]Lembo S,Megna M,Balato A,et al."Cowboy's belt with revolver"scleroderma caused by vitamin K1 injections[J].G Ital DermatolVenereol,2012(147):203-205.
[4]Mosterd K,Winnepenninckx V,Vermeulen A,et al.Morphea follow-ing surgery and radiotherapy:an evolving problem[J].J Eur AcadDermatol Venereol,2009(23):1099-1101.
[5]陈卫,杨蓉娅.硬皮病的治疗现状与展望[J].实用皮肤病学杂志,2015,8(5):367-370.
[6]黄帝内经·素问[M].田代华,整理.北京:人民卫生出版社,2005:85.
[7]巢元方.诸病源候论[M].北京:人民卫生出版社,1956:5.
[8]杨克勤.张怀亮教授治疗硬皮病经验[J].中医研究,2013,26(7):55-56.
[9]吴德鸿,李正富,范永升.范永升教授治疗硬皮病经验[J].中华中医药杂志,2015,30(6):1990-1992.
[10]王俊志,王喜,吴迪.白郡符老中医治疗硬皮病经验[J].光明中医,2016,31(7):929-930.
[11]李颖,周平安.周平安教授治疗硬皮病经验浅析[J].新中医,2012,44(3):154-156.
[12]柳丽,张洪泉.丹参活性成分的现代中药药理研究进展[J].中国野生植物资源,2003,22(6):1-4.
[13]邓家刚,梁宁,周程艳.鸡血藤药效及作用机理研究进展[J].广西中医药,2006,29(6):1-3.
[14]陈从显,徐爱钰,许勇,等.鸡血藤总黄酮对小鼠急性肝损伤的保护作用[J].滨州医学院学报,2012,35(3):189-191.
[15]曾粤.徐长卿的研究进展[J].内蒙古中医药,2012,31(11):125-126.
[16]杨璐.积雪草苷药理作用及其机制的研究进展[J].中华中医药学刊,2008,26(1):215-218.
[17]杨玉琴,丁永辉,夏玉凤.积雪草活性成分的分析方法及药理作用研究进展[J].中国野生植物资源,2010,29(3):6-9.
[18]吕超田,姚向阳,孙程.灵芝主要活性药物及其药理作用研究[J].安徽农业通报,2011,17(1):50-52.
[19]金培志,张建勇,李林.滋阴狼疮胶囊在系统性红斑狼疮激素撤减中的临床应用研究[J].河南中医学院学报,2006,21(4):21-22,24.
[20]查良伦,沈自尹,施凤英,等.补肾中药拮抗皮质激素所致副反应的实验观察[J].上海中医药杂志,1990,24(2):1-3.
[21]任志萍.黄芪现代药理学研究进展[J].中国民族民间医药,2010,19(3):35.
[22]黄伏顺.太子参的功效特点[J].江苏中医,1993,14(4):29-30.
[23]刘东,韩邦兴,姚厚军,等.太子参化学成分研究进展[J].中国民族民间医药,2014,23(16):18-20.