通幽合剂治疗儿童实热型功能性便秘疗效观察
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摘要
目的:观察通幽合剂治疗儿童实热型功能性便秘的临床疗效。方法:湖北省中医院儿科门诊2015年1月—2016年3月收治的80例功能性便秘患儿,采用随机数字表法随机分为两组,治疗组予自拟通幽合剂口服,对照组予麻子仁丸口服,观察各组治疗14 d后疗效,并随访28 d。结果:治疗14 d,通幽合剂组愈显率高于麻仁润肠丸组(P<0.05),两组排便间隔时间、大便干结、排便困难等主证评分均有改善,以治疗组为优(P<0.05)。结论:通幽合剂治疗儿童便秘临床效果显著,值得临床推广应用。
Objective: To observe the clinical effectiveness of Tongyou Heji treating children's functional constipation of excess-heat syndrome. Methods: 80 cases of functional constipation were randomly divided into the observation group and the control group. The observation group was given Tongyou Heji; whereas,the control group was given Maziren Wan. The clinical efficacy was observed after the 14-day treatment and during 28-day follow-up. Results: After 14 days of treatment,the curative rate was obviously higher in the observation group than that in the control group( P <0. 05). Significant improvement was observed in the scores of main symptoms,such as defecation interval,dry stool,difficult defecation,in both groups; of which,the observation group was superior to the control group( P < 0. 05). Conclusion: Tongyou Heji has remarkable effect on children's functional constipation,and it is worthy of clinical promotion.
Objective: To observe the clinical effectiveness of Tongyou Heji treating children's functional constipation of excess-heat syndrome. Methods: 80 cases of functional constipation were randomly divided into the observation group and the control group. The observation group was given Tongyou Heji; whereas,the control group was given Maziren Wan. The clinical efficacy was observed after the 14-day treatment and during 28-day follow-up. Results: After 14 days of treatment,the curative rate was obviously higher in the observation group than that in the control group( P <0. 05). Significant improvement was observed in the scores of main symptoms,such as defecation interval,dry stool,difficult defecation,in both groups; of which,the observation group was superior to the control group( P < 0. 05). Conclusion: Tongyou Heji has remarkable effect on children's functional constipation,and it is worthy of clinical promotion.
引文
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[3]齐妍枫.儿童便秘的危害及治疗[J].中国医药指南,2013,11(18):793-794.
[4]王宝西.儿童慢性便秘的临床特点及治疗[J].中国实用儿科杂志,2012,27(8):561-564.
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[7]陈洁.儿童功能性胃肠病的罗马Ⅲ诊断标准[J].中国实用儿科杂志,2007,22(1):1-3.
[8]中华人民共和国卫生部.中药新药临床研究指导原则(第三辑)[M].北京:中国医药卫生出版社,1997:3-4.
[9]唐元萍,谢德智,羊建华,等.308例小儿慢性便秘病因分析[J].齐齐哈尔医学院学报,2011,32(3):387-388.
[10]吕峻峰,熊勇.儿童及青少年功能性便秘流行病学调查及危险因素分析[J].中国妇幼保健,2012,27(21):3301-3303.
[11]陈瑶,刘建忠.小儿便秘中医辨证用药研究[J].湖北中医杂志,2017,39(7):9-11.
[2]Basquin,Di Lorenzo C,Forbes D,et al.Childhood functional gastrointestinal disorders:Child/adolescent[J].Gastroenterology,2006,130(5):1526-1537.
[3]齐妍枫.儿童便秘的危害及治疗[J].中国医药指南,2013,11(18):793-794.
[4]王宝西.儿童慢性便秘的临床特点及治疗[J].中国实用儿科杂志,2012,27(8):561-564.
[5]国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:57.
[6]中华中医药学会.中医内科常见病诊疗指南:中医病证部分[M].北京:中国中医药出版社,2008:95-97.
[7]陈洁.儿童功能性胃肠病的罗马Ⅲ诊断标准[J].中国实用儿科杂志,2007,22(1):1-3.
[8]中华人民共和国卫生部.中药新药临床研究指导原则(第三辑)[M].北京:中国医药卫生出版社,1997:3-4.
[9]唐元萍,谢德智,羊建华,等.308例小儿慢性便秘病因分析[J].齐齐哈尔医学院学报,2011,32(3):387-388.
[10]吕峻峰,熊勇.儿童及青少年功能性便秘流行病学调查及危险因素分析[J].中国妇幼保健,2012,27(21):3301-3303.
[11]陈瑶,刘建忠.小儿便秘中医辨证用药研究[J].湖北中医杂志,2017,39(7):9-11.