浓缩生长因子纤维蛋白对牙龈退缩的临床治疗作用效果研究
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摘要
<正>牙龈退缩表现为牙龈组织向根尖方向移动,使牙根暴露,还可引起牙齿敏感、根面龋和牙间隙增大等问题,并且影响美观,冠向复位瓣(CAF)联合结缔组织移植(CTG)虽然被认为是治疗牙龈退缩的金标准,但需要开辟第二术区、取自体组织,可导致术后疼痛和感染,加之治疗多颗牙牙龈退缩时往往需要大量的牙龈结缔组织,对于供瓣区有限的患者来说,临床治疗具有一定的局限性。浓缩生长因子纤维蛋白(CGF)为高浓度生长因子的纤维蛋白聚合物,通过变速离心
引文
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[2] Chambrone L,Chambrone D,Pustiglioni FE,et al. Can subepithelial connective tissue grafts be considered the gold standard procedure in the treatment of Miller Class I and II recession-type defects?[J]. J Dent,2008,36(9):659-671.
[3] Fennis JP,Stoelinga PJ,Jansen JA. Mandibular reconstruction:a histological and histomorphometric study on the use of autogenous scaffolds, particulate cortico-cancellous bone grafts and platelet rich plasma in goats[J]. Int J Oral Maxillofac Surg,2004,33(1):48-55.
[4] Giannobile WV,Whitson SW,Lynch SE. Non-coordinate control of bone formation displayed by growth factor combinations with IGF-I[J]. J Dent Res,1997,76(9):1569-1578.
[5] Kim TH,Kim SH,Sandor GK,et al. Comparison of platelet-rich plasma(PRP), platelet-rich fibrin(PRF), and concentrated growth factor(CGF)in rabbit-skull defect healing[J]. Arch Oral Biol,2014,59(5):550-558.