散偏汤治疗偏头痛文献的Meta分析
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摘要
目的采用Meta分析系统评价散偏汤治疗偏头痛的疗效及安全性。方法通过检索CNKI、万方、维普数据库,收集散偏汤治疗偏头痛的随机对照试验,使用Review Mananger 5.3软件进行Meta分析。结果合计纳入10篇文献,Meta分析结果显示:散偏汤能缓解偏头痛患者的疼痛及降低疼痛积分[RR=1.23,95%CI(1.14,1.31),P <0.00001],无明显不良反应。结论散偏汤可以有效治疗偏头痛,无明显不良反应,但由于纳入的文献质量不高,尚需开展更多高质量、多中心的随机对照试验加以支持。
Objective: To evaluate the efficacy and safety of Sanpian Decoction on migraine by Meta-analysis system. Methods: By retrieving CNKI,Wan Fang and VIP database,a randomized controlled trial was collected about the treatment of migraine,and the Meta-analysis was carried out by Review Mananger 5.3 software. Results: 10 articles were included. The results of Meta-analysis showed that sac could relieve the pain of migraine patients and reduce the pain score[RR=1.23,95%CI(1.14,1.31),P < 0.00001],without obvious adverse reactions.Conclusion: The decoction can effectively treat migraine without obvious side effects. But because the quality of the literature is not high,it is necessary to carry out more high quality and multicenter randomized controlled trials to support the conclusions.
Objective: To evaluate the efficacy and safety of Sanpian Decoction on migraine by Meta-analysis system. Methods: By retrieving CNKI,Wan Fang and VIP database,a randomized controlled trial was collected about the treatment of migraine,and the Meta-analysis was carried out by Review Mananger 5.3 software. Results: 10 articles were included. The results of Meta-analysis showed that sac could relieve the pain of migraine patients and reduce the pain score[RR=1.23,95%CI(1.14,1.31),P < 0.00001],without obvious adverse reactions.Conclusion: The decoction can effectively treat migraine without obvious side effects. But because the quality of the literature is not high,it is necessary to carry out more high quality and multicenter randomized controlled trials to support the conclusions.
引文
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[10]聂飞.活血散偏汤治疗偏头痛的效果观察[J].中国中医药现代远程教育,2014,12(24):140-141.
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[12]朱安龙,陈永龙.加味散偏汤治疗偏头痛38例观察[J].实用中医药杂志,2003,19(11):570.
[13]徐长青,付小燕.散偏汤加减治疗偏头痛59例[J].现代中医药,2009,29(4):22-23.
[14]马岱朝,陈文博,唐妍妍.散偏汤加昧治疗偏头痛82例[J].湖北省卫生职工医学院学报,2014,40(31):3.
[15]李炬明.散偏汤治疗偏头痛30例[J].中医临床研究,2010,2(17):37-38.
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[17]张文海.川芎的药理作用及临床应用[J].中国卫生标准管理,2015,6(26):117-118.
[18]李颖,魏新智.白芍不同炮制品的镇痛、镇静、抗炎作用比较[J].辽宁中医药大学学报,2016,18(4):39-41.
[19]侯家玉.中药药理学[M].北京:中国中医药出版社,2013:29-31.
[20]聂红,沈映君.白芷挥发油对伤害性疼痛模型大鼠基因表达的影响[J].中药新药与临床药理,2003,14(1):211.
[21]万军梅,黄红.白芥子不同提取部位抗炎镇痛作用研究[J].亚太传统医药,2014,10(5):39-41.
[22]李淑雯,胡志方.香附醋制前后对大鼠脊髓c-fos蛋白表达的影响[J].中药新药与临床药理,2013,24(2):129-131.
[23]夏其乐,王涛,陆胜民.苦杏仁苷的分析、提取纯化及药理作用研究进展[J].食品科学,2013,34(21):403-407.
[2]方积乾.生物医学研究的统计方法[M].北京:高等教育出版社,2007:502-503.
[3] Freiedman JH. Multivariate regression splines[J]. The annals of statistics,1989,19(1):1-14.
[4]方积乾.生物医学研究的统计方法[M].北京:高等教育出版社,2007:514.
[5]吕家春,施侣元. Meta-analysis及其在流行病学中的应用[J].中华流行病学杂志,1994,15(6):363.
[6]任冬冬,梁卓,崔应麟,等.加味散偏汤治疗风痰瘀阻型偏头痛46例临床观察[J].中医杂志,2017,58(3):231-234.
[7]申斌,于川,王磊,等.加味散偏汤颗粒剂治疗偏头痛肝郁血瘀型60例[J].中国中医药现代远程教育.2016,14(4):51-54.
[8]陈辉.散偏汤治疗偏头痛72例临床观察[J].中国中医急症,2012,21(6):962.
[9]叶通明.加味散偏汤治疗偏头痛48例临床观察[J].河南中医,2004,24(6):35.
[10]聂飞.活血散偏汤治疗偏头痛的效果观察[J].中国中医药现代远程教育,2014,12(24):140-141.
[11]黄伟明.散偏汤治疗偏头痛36例疗效观察[J].河北中医,2005,27(7):517-518.
[12]朱安龙,陈永龙.加味散偏汤治疗偏头痛38例观察[J].实用中医药杂志,2003,19(11):570.
[13]徐长青,付小燕.散偏汤加减治疗偏头痛59例[J].现代中医药,2009,29(4):22-23.
[14]马岱朝,陈文博,唐妍妍.散偏汤加昧治疗偏头痛82例[J].湖北省卫生职工医学院学报,2014,40(31):3.
[15]李炬明.散偏汤治疗偏头痛30例[J].中医临床研究,2010,2(17):37-38.
[16]侯家玉.中药药理学[M].北京:中国中医药出版社,2013:153-155.
[17]张文海.川芎的药理作用及临床应用[J].中国卫生标准管理,2015,6(26):117-118.
[18]李颖,魏新智.白芍不同炮制品的镇痛、镇静、抗炎作用比较[J].辽宁中医药大学学报,2016,18(4):39-41.
[19]侯家玉.中药药理学[M].北京:中国中医药出版社,2013:29-31.
[20]聂红,沈映君.白芷挥发油对伤害性疼痛模型大鼠基因表达的影响[J].中药新药与临床药理,2003,14(1):211.
[21]万军梅,黄红.白芥子不同提取部位抗炎镇痛作用研究[J].亚太传统医药,2014,10(5):39-41.
[22]李淑雯,胡志方.香附醋制前后对大鼠脊髓c-fos蛋白表达的影响[J].中药新药与临床药理,2013,24(2):129-131.
[23]夏其乐,王涛,陆胜民.苦杏仁苷的分析、提取纯化及药理作用研究进展[J].食品科学,2013,34(21):403-407.