血清铁蛋白在不同孕期妊娠妇女检测的临床意义
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  • 英文篇名:Clinical significance of serum ferritin in different gestation period detection for pregnant women
  • 作者:张微惠 ; 徐建民 ; 周丽银
  • 英文作者:ZHANG Wei-hui;XU Jian-min;ZHOU Li-yin;Guangdong Yunfu City Maternal and Child Health Family Planning Service Center;
  • 关键词:血清铁蛋白 ; 妊娠妇女 ; 临床意义
  • 英文关键词:Serum ferritin;;Pregnant women;;Clinical significance
  • 中文刊名:ZSSA
  • 英文刊名:China Practical Medicine
  • 机构:广东省云浮市妇幼保健计划生育服务中心;
  • 出版日期:2017-02-28
  • 出版单位:中国实用医药
  • 年:2017
  • 期:v.12
  • 语种:中文;
  • 页:ZSSA201706021
  • 页数:3
  • CN:06
  • ISSN:11-5547/R
  • 分类号:49-51
摘要
目的探讨不同孕期妊娠妇女血清铁蛋白(SF)水平的变化及临床意义。方法 823例行产前检查的不同孕期妊娠妇女定为观察组,根据孕期不同可分为早孕组(139例)、中孕组(193例)、晚孕组(491例),选择52例非妊娠妇女为对照组,分别检测血清铁蛋白含量、血红蛋白、红细胞分布宽度。结果随早、中、晚孕期的发展,血清铁蛋白含量、血红蛋白浓度呈明显下降趋势,以血清铁蛋白下降趋势最为明显。三组孕妇红细胞分布宽度比较差异无统计学意义(P>0.05);早孕组血清铁蛋白含量、血红蛋白浓度与对照组比较差异无统计学意义(P>0.05);中孕、晚孕组血清铁蛋白含量、血红蛋白浓度均低于对照组、早孕组,差异具有统计学意义(P<0.05);晚孕组血清铁蛋白含量、血红蛋白浓度低于中孕组,差异具有统计学意义(P<0.05)。观察组孕妇中检出120例缺铁性贫血,早孕组、中孕组、晚孕组各3例、14例和103例;321例铁蛋白缺乏,早孕组、中孕组、晚孕组各4例、16例和305例。随着孕周的增加,铁蛋白缺乏的患病率越来越高,贫血患病率也随之升高,差异均有统计学意义(P<0.05)。结论在不同孕期孕妇体内铁存储量不足,其中中期、晚期孕妇以缺铁为主要表现,应及时对他们进行铁剂的补充,保证胎儿的营养和正常发育,减少缺铁性贫血的发生有着重要的意义。
        Objective To investigate changes and clinical significance of serum ferritin(SF) levels in pregnant women of different gestation period. Methods There were 823 pregnant women of different gestation period in prenatal examination as observation group, and they were divided by different gestation period into early pregnancy group(139 cases), midterm pregnancy group(193 cases) and late pregnancy group(491 cases). There were another 52 women without pregnancy as control group. Detection was made on serum ferritin content, hemoglobin and red cell distribution width. Results With development from early pregnancy, midterm pregnancy and late pregnancy, serum ferritin content and hemoglobin concentration both showed obvious decline trend, and decline trend in serum ferritin was more remarkable. There was no statistically significant difference of red cell distribution width in the three groups(P>0.05). The difference of serum ferritin content and hemoglobin concentration between the early pregnancy group and the control group had no statistical significance(P>0.05). The midterm pregnancy group and the last pregnancy group had all lower serum ferritin content and hemoglobin concentration than the control group and the early pregnancy group, and their difference had statistical significance(P<0.05). The last pregnancy group had lower serum ferritin content and hemoglobin concentration than the midterm pregnancy group, and the difference had statistical significance(P<0.05). There were 120 cases with detected iron-deficiency anemia in the observation group, with respectively 3 cases in the early pregnancy group, 14 cases in the midterm pregnancy group and 103 cases in the late pregnancy group. Among 321 cases with ferritin deficiency, there were 4 cases in the early pregnancy group, 16 cases in the midterm pregnancy group and 305 cases in the late pregnancy group. Development of gestation period led to higher morbidity of ferritin deficiency and anemia, and the differences all had statistical significance(P<0.05). Conclusion Ion content varies in pregnant women of different gestation period, while iron deficiency is the main manifestation in midterm pregnancy and late pregnancy. It is essential for ion supplement to guarantee fetal nutrition and normal development. Reducing iron-deficiency anemia contains important significance.
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