植物油菜素内酯信号通路与植物免疫相关研究进展
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摘要
油菜素内酯是一种甾醇类植物激素,近年的研究表明其在植物生长发育等过程中起重要作用。近年来油菜素内酯与植物生长相关的研究不断被报道,但对于植物中油菜素内酯信号通路及其介导的植物防御反应分子机制的了解相对较少。对近年来油菜素内酯信号传导途径分子机制及其介导的植物对病原物等防御反应的研究进展进行综述。
Brassinosteroids(BRs)is a sterol phytohormone,and recent studies have shown that it plays an important role in plant growth and development.In recent years,there are lots of progresses in studies brassinosteroids in plant growth and development.However,there is little understanding of the molecular mechanisms of BRs signaling transduction and its functions in plant defensive responses.In this study,the research progresses of the molecular mechanism of BRs signaling pathway and plant defences of BRs against biological stresses were reviewed.
Brassinosteroids(BRs)is a sterol phytohormone,and recent studies have shown that it plays an important role in plant growth and development.In recent years,there are lots of progresses in studies brassinosteroids in plant growth and development.However,there is little understanding of the molecular mechanisms of BRs signaling transduction and its functions in plant defensive responses.In this study,the research progresses of the molecular mechanism of BRs signaling pathway and plant defences of BRs against biological stresses were reviewed.
引文
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[31] VERT G,CHORY J.Downstream nuclear events in brassinosteroid signalling[J].Nature,2006,441(7089):96-100.
[32] GENDRON J M,WANG Z Y.Multiple mechanisms modulate brassinosteroid signaling[J].Curr Opin Plant Biol,2007,10(5):436-441.
[33] TANG W Q,YUAN M,WANG R J,et al.PP2A activates brassinosteroid-responsive gene expression and plant growth by dephosphorylating BZR1[J].Nat Cell Biol,2011,13(2):124-131.
[34] WANG Z Y,NAKANO T,GENDRON J,et al.Nuclear-localized BZR1 mediates brassinosteroid-induced growth and feedback suppression of brassinosteroid biosynthesis[J].Dev Cell,2002,2(4):505-513.
[35] YU X F,LI L,ZOLA J,et al.A brassinosteroid transcriptional network revealed by genome-wide identification of BESI target genes in Arabidopsis thaliana[J].Plant J,2011,65(4):634-646.
[36] YIN Y H,VAFEADOS D,TAO Y,et al.A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis[J].Cell,2005,120(2):249-259.
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[40] NAKASHITA H,YASUDA M,NITTA T,et al.Brassinosteroid functions in a broad range of disease resistance in tobacco and rice[J].Plant J,2003,33(5):887-898.
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[42] KEMMERLING B,SCHWEDT A,RODRIGUEZ P,et al.The BRI1-associated kinase 1,BAK1,has a brassinolide-independent role in plant cell-death control[J].Curr Biol,2007,17(13):1116-1122.
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[44] CHAPARRO-GARCIA A,WILKINSON R C,GIMENEZ-IBANEZ S,et al.The receptor-like kinase SERK3/BAK1 is required for basal resistance against the late blight pathogen phytophthora infestans in Nicotiana benthamiana[J].PLoS One,2011,6(1):1-10.
[45] HEESE A,HANN D R,GIMENEZ-IBANEZ S,et al.The receptor-like kinase SERK3/BAK1 is a central regulator of innate immunity in plants[J].Proc Natl Acad Sci USA,2007,104(29):12217-12222.
[46] 陈丽霞,李英慧,郑服丛,等.油菜素内酯(BR)对大豆疫霉根腐病抗性的影响[J].大豆科学,2007,26(5):713-717.
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[50] BELKHADIR Y,JAILLAIS Y,EPPLE P,et al.Brassinosteroids modulate the efficiency of plant immune responses to microbe-associated molecular patterns[J].Proc Natl Acad Sci USA,2012,109(1):297-302.
[51] DE VLEESSCHAUWER D,VAN BUYTEN E,SATOH K,et al.Brassinosteroids antagonize gibberellin- and salicylate-mediated root immunity in rice[J].Plant Physiol,2012,158(4):1833-1846.
[52] NAHAR K,KYNDT T,HAUSE B,et al.Brassinosteroids suppress rice defense against root-knot nematodes through antagonism with the jasmonate pathway[J].Mol Plant Microbe Interact,2013,26(1):106-115.
[53] MALINOVSKY F G,BATOUX M,SCHWESSINGER B,et al.Antagonistic regulation of growth and immunity by the Arabidopsis basic helix-loop-helix transcription factor homolog of brassinosteroid enhanced expression2 interacting with increased leaf inclination1 binding bHLH1[J].Plant Physiol,2014,164(3):1443-1455.
[54] HALTER T,IMKAMPE J,MAZZOTTA S,et al.The leucine-rich repeat receptor kinase BIR2 is a negative regulator of BAK1 in plant immunity[J].Curr Biol,2014,24(2):134-143.
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[2] NISHIMURA M T,DANGL J L.Arabidopsis and the plant immune system[J].Plant J,2010,61(6):1053-1066.
[3] 蔡传杰,陈善娜.植物激素的研究进展[J].云南大学学报(自然科学版),2001,23(S1):99-101.
[4] THOMPSON M J,MEUDT W J,MANDAVA N B,et al.Synthesis of brassinosteroids and relationship of structure to plant growth-promoting effects[J].Steroids,1982,39(1):89-105.
[5] CLOUSE S D,SASSE J M.BRASSINOSTEROIDS:Essential regulators of plant growth and development[J].Annu Rev Plant Physiol Plant Mol Biol,1998,49:427-451.
[6] 邓天福,吴艳兵,李广领,等.油菜素内酯提高植物抗逆性研究进展[J].广东农业科学,2009(11):21-25.
[7] YAN H J,ZHAO Y F,SHI H,et al.BRASSINOSTEROID-SIGNALING KINASE1 phosphorylates MAPKKK5 to regulate immunity in Arabidopsis[J].Plant Physiol,2018,176(4):2991-3002.
[8] LIU Y N,HUANG X C,LI M,et al.Loss-of-function of Arabidopsis receptor-like kinase BIR1 activates cell death and defense responses mediated by BAK1 and SOBIR1[J].New Phytol,2016,212(3):637-645.
[9] HALTER T,IMKAMPE J,BLAUM B S,et al.BIR2 affects complex formation of BAK1 with ligand binding receptors in plant defense[J].Plant Signal Behav,2014,9:1-4.
[10] KIM T W,WANG Z Y.Brassinosteroid signal transduction from receptor kinases to transcription factors[J].Annu Rev Plant Biol,2010,61:681-704.
[11] SUN Y,FAN X Y,CAO D M,et al.Integration of brassinosteroid signal transduction with the transcription network for plant growth regulation in Arabidopsis[J].Dev Cell,2010,19(5):765-777.
[12] WANG X F,KOTA U,HE K,et al.Sequential transphosphorylation of the BRI1/BAK1 receptor kinase complex impacts early events in brassinosteroid signaling[J].Dev Cell,2008,15(2):220-235.
[13] KIM T W,GUAN S H,SUN Y,et al.Brassinosteroid signal transduction from cell-surface receptor kinases to nuclear transcription factors[J].Nat Cell Biol,2009,11(10):1254-1260.
[14] LI Y,ZHANG Q Q,ZHANG J G,et al.Identification of microRNAs involved in pathogen-associated molecular pattern-triggered plant innate immunity[J].Plant Physiol,2010,152(4):2222-2231.
[15] KINOSHITA T,CA A,SETO H,et al.Binding of brassinosteroids to the extracellular domain of plant receptor kinase BRI1[J].Nature,2005,433(7022):167-171.
[16] ZHOU A F,WANG H C,WALKER J C,et al.BRL1,a leucine-rich repeat receptor-like protein kinase,is functionally redundant with BRI1 in regulating Arabidopsis brassinosteroid signaling[J].Plant J,2004,40(3):399-409.
[17] LI J,WEN J Q,LEASE K A,et al.BAK1,an Arabidopsis LRR receptor-like protein kinase,interacts with BRI1 and modulates brassinosteroid signaling[J].Cell,2002,110(2):213-222.
[18] SHIU S H,BLEECKER A B.Plant receptor-like kinase gene family:Diversity,function,and signaling[J].Sci STKE,2001,113:1-13.
[19] SHE J,HAN Z F,KIM T W,et al.Structural insight into brassinosteroid perception by BRI1[J].Nature,2011,474(7352):472-476.
[20] WANG X L,CHORY J.Brassinosteroids regulate dissociation of BKI1,a negative regulator of BRI1 signaling,from the plasma membrane[J].Science,2006,313(5790):1118-1122.
[21] JAILLAIS Y,BELKHADIR Y,BALSEM E,et al.Extracellular leucine-rich repeats as a platform for receptor/coreceptor complex formation[J].Proc Natl Acad Sci USA,2011,108(20):8503-8507.
[22] JAILLAIS Y,HOTHORN M,BELKHADIR Y,et al.Tyrosine phosphorylation controls brassinosteroid receptor activation by triggering membrane release of its kinase inhibitor[J].Genes Dev,2011,25(3):232-237.
[23] TANG W Q,KIM T W,OSES-PRIETO J A,et al.BSKs mediate signal transduction from the receptor kinase BRI1 in Arabidopsis[J].Science,2008,321(5888):557-560.
[24] KIM T W,GUAN S H,BURLINGAME A L,et al.The CDG1 kinase mediates brassinosteroid signal transduction from BRI1 receptor kinase to BSU1 phosphatase and GSK3-like kinase BIN2[J].Mol Cell,2011,43(4):561-571.
[25] PENG P,ZHAO J,ZHU Y Y,et al.A direct docking mechanism for a plant GSK3-like kinase to phosphorylate its substrates[J].J Biol Chem.,2010,285(32):24646-24653.
[26] SREERAMULU S,MOSTIZKY Y,SUNITHA S,et al.BSKs are partially redundant positive regulators of brassinosteroid signaling in Arabidopsis[J].Plant J,2013,74(6):905-919.
[27] PENG P,YAN Z Y,ZHU Y Y,et al.Regulation of the Arabidopsis GSK3-like kinase BRASSINOSTEROID-INSENSITIVE 2 through proteasome-mediated protein degradation[J].Mol Plant,2008,1(2):338-346.
[28] RYU H,KIM K,CHO H,et al.Predominant actions of cytosolic BSU1 and nuclear BIN2 regulate subcellular localization of BES1 in brassinosteroid signaling[J].Mol Cells,2010,29(3):291-296.
[29] GAMPALA S S,KIM T W,HE J X,et al.An essential role for 14-3-3 proteins in brassinosteroid signal transduction in Arabidopsis[J].Dev Cell,2007,13(2):177-189.
[30] RYU H,KIM K,CHO H,et al.Nucleocytoplasmic shuttling of BZR1 mediated by phosphorylation is essential in Arabidopsis brassinosteroid signaling[J].Plant cell,2007,19(9):2749-2762.
[31] VERT G,CHORY J.Downstream nuclear events in brassinosteroid signalling[J].Nature,2006,441(7089):96-100.
[32] GENDRON J M,WANG Z Y.Multiple mechanisms modulate brassinosteroid signaling[J].Curr Opin Plant Biol,2007,10(5):436-441.
[33] TANG W Q,YUAN M,WANG R J,et al.PP2A activates brassinosteroid-responsive gene expression and plant growth by dephosphorylating BZR1[J].Nat Cell Biol,2011,13(2):124-131.
[34] WANG Z Y,NAKANO T,GENDRON J,et al.Nuclear-localized BZR1 mediates brassinosteroid-induced growth and feedback suppression of brassinosteroid biosynthesis[J].Dev Cell,2002,2(4):505-513.
[35] YU X F,LI L,ZOLA J,et al.A brassinosteroid transcriptional network revealed by genome-wide identification of BESI target genes in Arabidopsis thaliana[J].Plant J,2011,65(4):634-646.
[36] YIN Y H,VAFEADOS D,TAO Y,et al.A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis[J].Cell,2005,120(2):249-259.
[37] HE J X,GENDRON J M,SUN Y,et al.BZR1 is a transcriptional repressor with dual roles in brassinosteroid homeostasis and growth responses[J].Science,2005,307(5715):1634-1638.
[38] LI J M,JIN H.Regulation of brassinosteroid signaling[J].Trends Plant Sci,2007,12(1):37-41.
[39] RYU H,CHO H,KIM K,et al.Phosphorylation dependent nucleocytoplasmic shuttling of BES1 is a key regulatory event in brassinosteroid signaling[J].Mol Cells,2010,29(3):283-290.
[40] NAKASHITA H,YASUDA M,NITTA T,et al.Brassinosteroid functions in a broad range of disease resistance in tobacco and rice[J].Plant J,2003,33(5):887-898.
[41] KHRIPACH V,ZHABINSKII V,DE GROOT A.Twenty years of brassinosteroids:Steroidal plant hormones warrant better crops for the XXI century[J].Annals of botany,2000,86(3):441-447.
[42] KEMMERLING B,SCHWEDT A,RODRIGUEZ P,et al.The BRI1-associated kinase 1,BAK1,has a brassinolide-independent role in plant cell-death control[J].Curr Biol,2007,17(13):1116-1122.
[43] MARCOS R,IZQUIERDO Y,VELLOSILLO T,et al.9-Lipoxygenase-derived oxylipins activate brassinosteroid signaling to promote cell wall-based defense and limit pathogen infection[J].Plant physiology,2015,169(3):992-2015.
[44] CHAPARRO-GARCIA A,WILKINSON R C,GIMENEZ-IBANEZ S,et al.The receptor-like kinase SERK3/BAK1 is required for basal resistance against the late blight pathogen phytophthora infestans in Nicotiana benthamiana[J].PLoS One,2011,6(1):1-10.
[45] HEESE A,HANN D R,GIMENEZ-IBANEZ S,et al.The receptor-like kinase SERK3/BAK1 is a central regulator of innate immunity in plants[J].Proc Natl Acad Sci USA,2007,104(29):12217-12222.
[46] 陈丽霞,李英慧,郑服丛,等.油菜素内酯(BR)对大豆疫霉根腐病抗性的影响[J].大豆科学,2007,26(5):713-717.
[47] 刘庆.24-表油菜素内酯诱导葡萄抵抗霜霉病和灰霉病的研究[D].杨凌:西北农林科技大学,2016.
[48] LEE J,BRICKER T M,LEFEVRE M,et al.Proteomic and genetic approaches to identifying defence-related proteins in rice challenged with the fungal pathogen Rhizoctonia solani[J].Mol Plant Pathol,2006,7(5):405-416.
[49] ALBRECHT C,BOUTROT F,SEGONZAC C,et al.Brassinosteroids inhibit pathogen-associated molecular pattern-triggered immune signaling independent of the receptor kinase BAK1[J] Proc Natl Acad Sci USA,2012,109(1):303-308.
[50] BELKHADIR Y,JAILLAIS Y,EPPLE P,et al.Brassinosteroids modulate the efficiency of plant immune responses to microbe-associated molecular patterns[J].Proc Natl Acad Sci USA,2012,109(1):297-302.
[51] DE VLEESSCHAUWER D,VAN BUYTEN E,SATOH K,et al.Brassinosteroids antagonize gibberellin- and salicylate-mediated root immunity in rice[J].Plant Physiol,2012,158(4):1833-1846.
[52] NAHAR K,KYNDT T,HAUSE B,et al.Brassinosteroids suppress rice defense against root-knot nematodes through antagonism with the jasmonate pathway[J].Mol Plant Microbe Interact,2013,26(1):106-115.
[53] MALINOVSKY F G,BATOUX M,SCHWESSINGER B,et al.Antagonistic regulation of growth and immunity by the Arabidopsis basic helix-loop-helix transcription factor homolog of brassinosteroid enhanced expression2 interacting with increased leaf inclination1 binding bHLH1[J].Plant Physiol,2014,164(3):1443-1455.
[54] HALTER T,IMKAMPE J,MAZZOTTA S,et al.The leucine-rich repeat receptor kinase BIR2 is a negative regulator of BAK1 in plant immunity[J].Curr Biol,2014,24(2):134-143.
[55] KORNER C J,KLAUSER D,NIEHL A,et al.The immunity regulator BAK1 contributes to resistance against diverse RNA viruses[J].Mol Plant Microbe Interact,2013,26(11):1271-1280.
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