加味苓桂术甘汤联合管石复位法治疗良性阵发性位置性眩晕临床研究
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摘要
目的:观察加味苓桂术甘汤联合管石复位法治疗良性阵发性位置性眩晕(BPPV)的临床疗效。方法:将90例BPPV患者被随机分为2组,对照组45例采用常规治疗,观察组45例采用加味苓桂术甘汤联合管石复位法治疗;分别于治疗3、7天统计2组中医证候积分,疗程结束后评价临床疗效,随访3月统计复发率。结果:治疗3、7天,2组中医证候积分均较治疗前明显降低(P <0.05);且观察组积分下降较对照组同时间点更显著(P <0.05)。疗程结束后,治愈率、总有率观察组分别为68.8%、97.7%,对照组分别为35.5%、84.4%,2组比较,差异均有统计学意义(P <0.05)。复发率观察组为2.2%,对照组为17.8%,2组比较,差异有统计学意义(P <0.05)。结论:加味苓桂术甘汤联合管石复位法治疗BPPV,能明显提高临床疗效,减少复发率。
Objective:To observe the clinical effect of modified Linggui Zhugan tang combined with canalith repositioning method for benign paroxysmal positional vertigo(BPPV). Methods:A total of 90 cases of patients with BPPV were randomly divided into two groups,45 cases in each group. The control group was given the routine treatment. The observation group was given modified Linggui Zhugan tang combined with canalith repositioning method for treatment. At the third and seventh day after treatment, the scores of Chinese medicine syndrome in the two groups were observed respectively. The clinical effect was evaluated after the course of treatment and the recurrence rate was observed after 3 months follow-up. Results:At the third and seventh day after treatment,the scores of Chinese medicine syndrome in the two groups were significantly decreased when compared with those before treatment(P < 0.05),and the scores of Chinese medicine syndrome at the same time points in the observation group was decreased more significantly than that in the control group(P < 0.05). After the course of treatment,the cure rate and the total effective rate in the observation group were respectively 68.8% and 97.7%, and were respectively 35.5% and 84.4% in the control group, differences being significant(P < 0.05). The recurrence rate was2.2% in the observation group and was 17.8% in the control group, the difference being significant(P < 0.05). Conclusion:The therapy of modified Linggui Zhugan tang combined with canalith repositioning method for BPPV can significantly improve the clinical effect of patients and reduce the recurrence rate.
Objective:To observe the clinical effect of modified Linggui Zhugan tang combined with canalith repositioning method for benign paroxysmal positional vertigo(BPPV). Methods:A total of 90 cases of patients with BPPV were randomly divided into two groups,45 cases in each group. The control group was given the routine treatment. The observation group was given modified Linggui Zhugan tang combined with canalith repositioning method for treatment. At the third and seventh day after treatment, the scores of Chinese medicine syndrome in the two groups were observed respectively. The clinical effect was evaluated after the course of treatment and the recurrence rate was observed after 3 months follow-up. Results:At the third and seventh day after treatment,the scores of Chinese medicine syndrome in the two groups were significantly decreased when compared with those before treatment(P < 0.05),and the scores of Chinese medicine syndrome at the same time points in the observation group was decreased more significantly than that in the control group(P < 0.05). After the course of treatment,the cure rate and the total effective rate in the observation group were respectively 68.8% and 97.7%, and were respectively 35.5% and 84.4% in the control group, differences being significant(P < 0.05). The recurrence rate was2.2% in the observation group and was 17.8% in the control group, the difference being significant(P < 0.05). Conclusion:The therapy of modified Linggui Zhugan tang combined with canalith repositioning method for BPPV can significantly improve the clinical effect of patients and reduce the recurrence rate.
引文
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[5] Epley J.The canalith repositioning procedure:for treatment of benign paroxysmal positional vertigo[J].Otolaryngol Head Neck Surg,1992,107(3):399-404.
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[7]国家中医药管理局医政司.22个专业95个病种中医诊疗法案[M].北京:中国中医药出版社,2011:24.
[8]中华医学会神经病学分会,中华神经科杂志编辑委员会.2010年眩晕诊治专家共识[J].中华神经科杂志,2010,43(5):369-374.
[9]杨燕珍,黄静辉,林怀治.前庭康复训练在眩晕疾病治疗中的应用[J].中国康复医学杂志,2010,25(3):570-572.
[10]刘红芸,王晓良.苓桂术甘汤加减治疗痰饮病举隅[J].中国中医急症,2014,23(8):1574-1575.
[11]杜自亮.苓桂术甘汤治疗痰饮型眩晕病的临床效果[J].药物与临床,2016,13(1):41-45.
[2]熊彬彬,吴子明,刘兴健,等.良性阵发性位置性眩晕的临床特征分析[J].中华耳科学杂志,2012,10(2):208-211.
[3]中华医学会耳鼻咽喉头颈外科编辑委员会,中华医学会耳鼻咽喉科学分会.良性阵发性位置性眩晕的诊断依据和疗效评估(2006年,贵阳)[J].中华耳鼻喉头颈外科杂志,2007,42(2):163-164.
[4]郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002:361-364.
[5] Epley J.The canalith repositioning procedure:for treatment of benign paroxysmal positional vertigo[J].Otolaryngol Head Neck Surg,1992,107(3):399-404.
[6]邢光前,陈智斌,行宽.水平半规管良性阵发性位置性眩晕的治疗[J].中华耳鼻咽喉科杂志,2001,36(1):28-30.
[7]国家中医药管理局医政司.22个专业95个病种中医诊疗法案[M].北京:中国中医药出版社,2011:24.
[8]中华医学会神经病学分会,中华神经科杂志编辑委员会.2010年眩晕诊治专家共识[J].中华神经科杂志,2010,43(5):369-374.
[9]杨燕珍,黄静辉,林怀治.前庭康复训练在眩晕疾病治疗中的应用[J].中国康复医学杂志,2010,25(3):570-572.
[10]刘红芸,王晓良.苓桂术甘汤加减治疗痰饮病举隅[J].中国中医急症,2014,23(8):1574-1575.
[11]杜自亮.苓桂术甘汤治疗痰饮型眩晕病的临床效果[J].药物与临床,2016,13(1):41-45.