比伐卢定在择期冠状动脉介入治疗术中抗凝治疗的效果观察
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摘要
目的对于比伐卢定在择期冠状动脉介入治疗术中抗凝治疗的效果情况进行观察及分析。方法选取在本院接受治疗的120例择期实施冠状动脉介入治疗术患者作为研究对象,分成应用普通肝素抗凝治疗的参照组,以及应用比伐卢定抗凝治疗的研究组,各60例。对比两组患者的治疗成效。结果通过比较两组患者的冠状动脉介入治疗术成功率、凝血效果,组间比较差异无统计学意义;比较出血不良反应发生率,研究组明显的低于参照组,差异具有统计学意义(P<0.05)。结论对择期冠状动脉介入治疗术中抗凝治疗的患者采取比伐卢定,可以具备更好的安全可靠性。
Objective To observe and analyzethe effect of bivaludine on anticoagulant therapy during selective coronary intervention. Methods 120 patients who underwent coronary intervention in our hospital were selected as the study subjects. They were divided into the reference group for the application of heparin anticoagulant therapy and the study group for the application of bivaluddin anticoagulant therapy, 60 patients in each group.The therapeutic effects of the two groups were compared. Results There was no significant difference between the two groups in the success rate and coagulation effect of coronary intervention in the two groups. The incidence of adverse reactions to bleeding was significantly lower in the study group than in the control group, The difference was statistically significant(P<0.05). Conclusion The safety and reliability of selective coronary intervention in patients with anticoagulant therapy can be better than that of avalodin.
Objective To observe and analyzethe effect of bivaludine on anticoagulant therapy during selective coronary intervention. Methods 120 patients who underwent coronary intervention in our hospital were selected as the study subjects. They were divided into the reference group for the application of heparin anticoagulant therapy and the study group for the application of bivaluddin anticoagulant therapy, 60 patients in each group.The therapeutic effects of the two groups were compared. Results There was no significant difference between the two groups in the success rate and coagulation effect of coronary intervention in the two groups. The incidence of adverse reactions to bleeding was significantly lower in the study group than in the control group, The difference was statistically significant(P<0.05). Conclusion The safety and reliability of selective coronary intervention in patients with anticoagulant therapy can be better than that of avalodin.
引文
[1]刘育慧,任志学,张淑兰,等.用比伐卢定和肝素对行经皮冠状动脉介入术的老年心肌梗死患者实施抗凝治疗的效果对比[J].当代医药论丛,2017,15(11):17-18.
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[4]姜海兵,李岚,葛振嵘,等.替罗非班治疗比伐卢定抗凝下急性ST段抬高性心肌梗死经皮冠状动脉介入术中无复流或慢血流[J].中国新药与临床杂志,2015,34(11):884-888.
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[6]王峰,李田昌.行经皮冠状动脉介入治疗术患者合并心房颤动时抗凝的研究[J].转化医学杂志,2017,6(2):99-102.
[7]刘永兴,徐泽升,彭万忠,等.冠状动脉介入治疗术中发生冠状动脉穿孔的危险因素及治疗策略分析[J].中国心血管杂志,2016,21(3):213-217.
[8]吴佳纬,马礼坤,杨喆,等.比伐芦定在急性ST段抬高型心肌梗死患者急诊经皮冠状动脉介入治疗术中应用的疗效观察[J].中国循环杂志,2015,30(8):737-740.
[2]尹成彬.比伐卢定在急性ST段抬高型心肌梗死患者急诊经皮冠状动脉介入治疗术中的抗凝效果观察[J].实用心脑肺血管病杂志,2016,24(7):156-158.
[3]黄伟光.国产比伐卢定抗凝治疗在急诊经皮冠状动脉介入治疗中应用价值[J].现代诊断与治疗,2016,27(1):149-150.
[4]姜海兵,李岚,葛振嵘,等.替罗非班治疗比伐卢定抗凝下急性ST段抬高性心肌梗死经皮冠状动脉介入术中无复流或慢血流[J].中国新药与临床杂志,2015,34(11):884-888.
[5]林星,罗素新.ST段抬高型心肌梗死直接经皮冠状动脉介入术中抗凝治疗:肝素抑或比伐卢定[J].心血管病学进展,2015,36(3):308-311.
[6]王峰,李田昌.行经皮冠状动脉介入治疗术患者合并心房颤动时抗凝的研究[J].转化医学杂志,2017,6(2):99-102.
[7]刘永兴,徐泽升,彭万忠,等.冠状动脉介入治疗术中发生冠状动脉穿孔的危险因素及治疗策略分析[J].中国心血管杂志,2016,21(3):213-217.
[8]吴佳纬,马礼坤,杨喆,等.比伐芦定在急性ST段抬高型心肌梗死患者急诊经皮冠状动脉介入治疗术中应用的疗效观察[J].中国循环杂志,2015,30(8):737-740.