地塞米松注射液治疗上呼吸道感染的临床不良反应情况分析
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摘要
目的了解上呼吸道感染患者用地塞米松注射液治疗后引发相关不良反应情况。方法分析对象来自2014年1月—2016年12月于本院确诊为上呼吸道感染并接受治疗患者,从中抽取100例,根据患者接受治疗方案差异,将其以每组50例分为对照组(常规上呼吸道感染对症治疗)和观察组(对症联合地塞米松注射液治疗)。通过记录患者各项指标以了解地塞米松注射液对上呼吸道感染治疗的不良反应情况。结果两组患者在接受治疗期间均有药物相关不良反应发生,观察组患者发生低血钾、心律不齐、四肢无力等例数高于对照组,差异有统计学意义(P<0.05);观察组患者体温恢复正常以及平均病程时间与对照组患者相比,差异有统计学意义(P<0.05)。结论上呼吸道感染患者在对症抗感染治疗基础上联合地塞米松注射液,能够在更短时间内让体温恢复正常,但不良反应更为突出和明显,延长治疗后康复所需时间,应谨慎使用。
Objective To investigate the adverse reactions induced by dexamethasone injection in patients with upper respiratory tract infection.Methods From January 2014 to December 2016 in our hospital diagnosed as upper respiratory tract infection and treated patients, were selected from 100 cases of patients were treated according to the difference scheme with 50 cases in each group were randomly divided into control group(conventional symptomatic treatment of upper respiratory tract infection) and observationgroup(dexamethasone injection in the treatment of symptomatic).Objective to investigate the adverse reactions of dexamethasone injection in the treatment of upper respiratory tract infection. Results Two groups of patients in treatment have occurred during drug related adverse reactions,patients in the observation group of hypokalemia and arrhythmia, limb weakness and the number of cases was significantly higher than the control group, statistical software processing data to prompt meaningful differences(P<0.05); patients in the observation group, the average duration of body temperature returned to normal time compared with patients in the control group were statistically significant, suggesting significant statistical software for data processing(P<0.05). Conclusion Anti infection in patients with symptomatic treatment combined with dexamethasone injection on upper respiratory tract infection, can make the body temperature returned to normal in a shorter time, but the adverse reaction is more obvious, after prolonged treatment time required for rehabilitation, should be used with caution.
Objective To investigate the adverse reactions induced by dexamethasone injection in patients with upper respiratory tract infection.Methods From January 2014 to December 2016 in our hospital diagnosed as upper respiratory tract infection and treated patients, were selected from 100 cases of patients were treated according to the difference scheme with 50 cases in each group were randomly divided into control group(conventional symptomatic treatment of upper respiratory tract infection) and observationgroup(dexamethasone injection in the treatment of symptomatic).Objective to investigate the adverse reactions of dexamethasone injection in the treatment of upper respiratory tract infection. Results Two groups of patients in treatment have occurred during drug related adverse reactions,patients in the observation group of hypokalemia and arrhythmia, limb weakness and the number of cases was significantly higher than the control group, statistical software processing data to prompt meaningful differences(P<0.05); patients in the observation group, the average duration of body temperature returned to normal time compared with patients in the control group were statistically significant, suggesting significant statistical software for data processing(P<0.05). Conclusion Anti infection in patients with symptomatic treatment combined with dexamethasone injection on upper respiratory tract infection, can make the body temperature returned to normal in a shorter time, but the adverse reaction is more obvious, after prolonged treatment time required for rehabilitation, should be used with caution.
引文
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[2]朱美勤.地塞米松磷酸钠注射液治疗后常见不良反应表现及影响[J].临床研究,2016,24(12):168-169.
[3]张北平.地塞米松治疗上呼道感染的疗效与不良反应研究[J].现代养生,2016,41(7):89.
[4]方万芬,刘子龙,赵磊.热毒宁与利巴韦林治疗急性上呼吸道感染患儿的临床疗效比较[J].中华医院感染学杂志,2015,15(15):3572-3574.
[5]卢春生,李丽.地塞米松辅助治疗上呼吸道感染致高热的利弊分析[J].吉林医药学院学报,2015,36(5):358-359.
[6]杨晓阳.急性上呼吸道感染患者输液后急性低钾血症的原因分析[J].河南医学研究,2015,24(1):93-94.
[7]庄桃.热毒宁注射液治疗小儿病毒性上呼吸道感染的临床疗效观察[J].实用心脑肺血管病杂志,2015,23(2):110-111.
[8]苏剑波.地塞米松注射液治疗成人上呼吸道感染的疗效观察[J].健康必读,2012,11(8):266.
[9]辛忠.分析急诊治疗上呼吸道感染的用药合理性[J].中国继续医学教育,2016,8(30):121-122.