腹腔镜结直肠癌根治术患者围术期机体代谢及胃肠功能的变化观察
|
摘要
目的观察腹腔镜结直肠癌根治术患者围术期机体代谢及胃肠功能的变化情况。方法将行根治术治疗的56例结直肠癌患者作为研究对象,将56例手术患者随机分为对照组(常规开腹手术组)28例和观察组(腹腔镜手术组)28例。检测与比较两组手术患者围术期的蛋白代谢指标、脂代谢指标及胃肠功能指标。结果术前两组患者的蛋白代谢指标、脂代谢指标及胃肠功能指标均无明显差异(P均>0.05),而术后两组的蛋白代谢指标、脂代谢指标及胃肠功能指标均存在显著性差异,且观察组均显著地好于对照组(P均<0.05)。结论腹腔镜结直肠癌根治术患者围术期机体代谢及胃肠功能指标波动小于开腹手术,因此认为腹腔镜根治术更为适用于结直肠癌患者。
Objective To observe the change situation of body metabolism and gastrointestinal function of patients with laparoscopic radical resection of colorectal cancer during the perioperative period. Methods 56 patients with colorectal cancer who were treated with radical resection were selected,and 56 surgical patients were randomly divided into the control group( conventional open surgery group) and the observation group( laparoscopic surgery group),each group with 28 cases,then protein metabolism indexes,lipid metabolism indexes and gastrointestinal function indexes of surgical patients in the 2 groups during the perioperative period were detected and compared. Results The protein metabolism indexes,lipid metabolism indexes and gastrointestinal function indexes of surgical patients in the 2 groups before the surgery had no obvious differences( all P > 0. 05),while the protein metabolism indexes,lipid metabolism indexes and gastrointestinal function indexes of surgical patients in the 2 groups after the surgery all had significant differences,and the results of the observation group were significantly better than those of the control group( all P < 0. 05). Conclusion The body metabolism and gastrointestinal function indexes' fluctuations of patients with laparoscopic radical resection of colorectal cancer during the perioperative period are smaller than those of open surgery,so the laparoscopic radical resection is more suitable to the patients with colorectal cancer.
Objective To observe the change situation of body metabolism and gastrointestinal function of patients with laparoscopic radical resection of colorectal cancer during the perioperative period. Methods 56 patients with colorectal cancer who were treated with radical resection were selected,and 56 surgical patients were randomly divided into the control group( conventional open surgery group) and the observation group( laparoscopic surgery group),each group with 28 cases,then protein metabolism indexes,lipid metabolism indexes and gastrointestinal function indexes of surgical patients in the 2 groups during the perioperative period were detected and compared. Results The protein metabolism indexes,lipid metabolism indexes and gastrointestinal function indexes of surgical patients in the 2 groups before the surgery had no obvious differences( all P > 0. 05),while the protein metabolism indexes,lipid metabolism indexes and gastrointestinal function indexes of surgical patients in the 2 groups after the surgery all had significant differences,and the results of the observation group were significantly better than those of the control group( all P < 0. 05). Conclusion The body metabolism and gastrointestinal function indexes' fluctuations of patients with laparoscopic radical resection of colorectal cancer during the perioperative period are smaller than those of open surgery,so the laparoscopic radical resection is more suitable to the patients with colorectal cancer.
引文
[1]李永明.经腹腔镜结直肠癌根治术的疗效及对胃肠功能的影响[J].医疗装备,2016,29(1):97-98.
[2]宋胜江,张素惠,苏龙丰,等.腹腔镜与开腹手术在结直肠癌治疗中的应用对比[J].浙江创伤外科,2015,20(5):861-863.
[3]汤雪峰,李财宝,刘岗,等.腹腔镜微创手术与传统开腹手术对结直肠癌患者免疫和生理功能影响的临床观察[J].标记免疫分析与临床,2015,22(4):278-281.
[4]吴邦学,魏寿江.腹腔镜结直肠癌根治术在Ⅱ、Ⅲ期结直肠癌中的应用效果[J].实用临床医药杂志,2016,20(15):103-105.
[5]Julien M,Dove J,Quindlen K,et al.Evolution of Laparoscopic Surgery for Colorectal Cancer:The Impact of the Clinical Outcomes of Surgical Therapy Group Trial[J].Am Surg,2016,82(8):685-691.
[6]Allaix ME,Furnée EJ,Mistrangelo M,et al.Conversion of laparoscopic colorectal resection for cancer:What is the impact on short-term outcomes and survival?[J].World J Gastroenterol,2016,22(37):8304-8313.
[7]王帅奇,赵和照,胡正川.腹腔镜结直肠癌根治术对结直肠癌患者预后及胃肠激素的影响分析[J].中国医学前沿杂志(电子版),2015,7(12):54-57.
[8]苗大壮,刘正,王锡山.代谢异常对结直肠癌发病的影响[J].中华消化外科杂志,2014,13(12):995-998.
[9]曹子龙,任霖霖,马竟优,等.进展期结直肠癌血清白蛋白下降与IL-6、TNF-α和CRP的相关性研究[J].转化医学电子杂志,2015,2(5):76-78.
[2]宋胜江,张素惠,苏龙丰,等.腹腔镜与开腹手术在结直肠癌治疗中的应用对比[J].浙江创伤外科,2015,20(5):861-863.
[3]汤雪峰,李财宝,刘岗,等.腹腔镜微创手术与传统开腹手术对结直肠癌患者免疫和生理功能影响的临床观察[J].标记免疫分析与临床,2015,22(4):278-281.
[4]吴邦学,魏寿江.腹腔镜结直肠癌根治术在Ⅱ、Ⅲ期结直肠癌中的应用效果[J].实用临床医药杂志,2016,20(15):103-105.
[5]Julien M,Dove J,Quindlen K,et al.Evolution of Laparoscopic Surgery for Colorectal Cancer:The Impact of the Clinical Outcomes of Surgical Therapy Group Trial[J].Am Surg,2016,82(8):685-691.
[6]Allaix ME,Furnée EJ,Mistrangelo M,et al.Conversion of laparoscopic colorectal resection for cancer:What is the impact on short-term outcomes and survival?[J].World J Gastroenterol,2016,22(37):8304-8313.
[7]王帅奇,赵和照,胡正川.腹腔镜结直肠癌根治术对结直肠癌患者预后及胃肠激素的影响分析[J].中国医学前沿杂志(电子版),2015,7(12):54-57.
[8]苗大壮,刘正,王锡山.代谢异常对结直肠癌发病的影响[J].中华消化外科杂志,2014,13(12):995-998.
[9]曹子龙,任霖霖,马竟优,等.进展期结直肠癌血清白蛋白下降与IL-6、TNF-α和CRP的相关性研究[J].转化医学电子杂志,2015,2(5):76-78.