不同体温及PaCO_2对老年患者腹腔镜术后早期精神改变的影响
|
摘要
目的探讨不同水平的体温及PaCO_2对老年患者腹腔镜术后早期精神改变的影响。方法纳入在择期、全麻下行腹腔镜胃癌根治术的患者120例,随机分为4组,每组30例。对照组(N组)(35℃ Objective To investigate the effects of different levels of body temperature and PaCO_2 on early postoperative mental change in elderly patients,who underwent elective laparoscopic surgery. Methods Totally 120 patients over60 years of age,who were diagnosed with gastric carcinoma and scheduled for laparoscopic radical surgery,were randomly divided into four groups( n = 30 in each group) : control group with 35 ℃ < T < 36℃ and PaCO_235-45 mm Hg( group N),normothermia group with T≥36°and PaCO_235-45 mm Hg( group T),hypercapnia group with 35 ℃
引文
[1]Duong TQ,Iadecola C,Kim SG.Effect of hyperoxia,hypercapnia,and hypoxia on cerebral interstitial oxygen tension and cerebral blood flow[J].Magn Reson Med,2001,45(1):61-70.
[2]De Campos T.Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.The Acute Respiratory Distress Syndrome Network[J].Survey of Anesthesiology,2001,45(18):1301-1308.
[3]Carlo WA.Permissive hypercapnia and permissive hypoxemia in neonates[J].J Perinatol,2007,27:64-70.
[4]Sessler DI.Perioperative hypothermia in the high-risk surgical patient[J].Best Pract Res Clin Anaesthesiol,2003,17(4):485-498.
[5]Wagner VD.Impact of perioperative temperature management on patient safety[J].Surg Servi Manag,2003,9(4):38-43.
[6]Przybylo HJ,Martini DR,Mazurek AJ,et al.Assessing behaviour in children emerging from anaesthesia:can we apply psychiatric diagnostic techniques?[J].Pediatr Anesth,2003,13(7):609-616.
[7]Matsukawa T,Sessler DI,Sessler AM,et al.Heat flow and distribution during induction of general anesthesia[J].Anesthesiology,1995,82(3):662-673.
[8]Kurz A,Sessler DI,Christensen R,et al.Heat balance and distribution during the core-temperature plateau in anesthetized humans[J].Anesthesiology,1995,83(3):491-499.
[9]Mcdaniel M,Brudney C.Postoperative delirium:etiology and management[J].Curr Opin Crit Care,2012,18(4):372-376.
[10]Munster BC,Aronica E,Zwinderman AH,et al.Neuro inflammation in delirium:a postmortem case-control study[J].Rejuvenation Res,2011,14(6):615-622.
[11]Eckenhoff RG,Laudansky KF.Anesthesia,surgery,illness and Alzheimer's disease[J].Prog Neuropsychopharmacol Biol Psychiatry,2013,47:162-166.
[12]Terrando N,Eriksson LI,Ryu JK,et al.Resolving postoperative neuroinflammation and cognitive decline[J].Ann Neurol,2011,70(6):986-995.
[13]Akca O,Liem E,Suleman MI,et al.Effect of intra-operative end-tidalcarbon dioxide partial pressure on tissue oxygenation[J].Anaesthesia,2003,58(6):536-542.
[14]Sicard KM,Duong TQ.Effects of hypoxia,hyperoxia,and hypercapnia on baseline and stimulus-evoked BOLD,CBF,and CMRO 2 in spontaneously breathing animals[J].Neuroimage,2005,25(3):850-858.
[15]Jones M,Berwick J,Hewson-Stoate N,et al.The effect of hypercapnia on the neural and hemodynamic responses to somatosensory stimulation[J].Neuroimage,2005,27(3):609-623.
[16]Vannucci RC,Brucklacher RM,Vannucci SJ.Effect of carbon dioxide on cerebral metabolism during hypoxiaischemia in the immature rat[J].Pediatr Res,1997,42(1):24-29.
[17]Zappe AC,Uluda K,Oeltermann A,et al.The influence of moderate hypercapnia on neural activity in the anesthetized nonhuman primate[J].Cereb Cortex,2008,18(11):2666-2673.
[18]Salazar F,Donate M,Boget T,et al.Intraoperative warming and post-operative cognitive dysfunction after total knee replacement[J].Acta Anaesthesiol Scand,2011,55(2):216-222.
[2]De Campos T.Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.The Acute Respiratory Distress Syndrome Network[J].Survey of Anesthesiology,2001,45(18):1301-1308.
[3]Carlo WA.Permissive hypercapnia and permissive hypoxemia in neonates[J].J Perinatol,2007,27:64-70.
[4]Sessler DI.Perioperative hypothermia in the high-risk surgical patient[J].Best Pract Res Clin Anaesthesiol,2003,17(4):485-498.
[5]Wagner VD.Impact of perioperative temperature management on patient safety[J].Surg Servi Manag,2003,9(4):38-43.
[6]Przybylo HJ,Martini DR,Mazurek AJ,et al.Assessing behaviour in children emerging from anaesthesia:can we apply psychiatric diagnostic techniques?[J].Pediatr Anesth,2003,13(7):609-616.
[7]Matsukawa T,Sessler DI,Sessler AM,et al.Heat flow and distribution during induction of general anesthesia[J].Anesthesiology,1995,82(3):662-673.
[8]Kurz A,Sessler DI,Christensen R,et al.Heat balance and distribution during the core-temperature plateau in anesthetized humans[J].Anesthesiology,1995,83(3):491-499.
[9]Mcdaniel M,Brudney C.Postoperative delirium:etiology and management[J].Curr Opin Crit Care,2012,18(4):372-376.
[10]Munster BC,Aronica E,Zwinderman AH,et al.Neuro inflammation in delirium:a postmortem case-control study[J].Rejuvenation Res,2011,14(6):615-622.
[11]Eckenhoff RG,Laudansky KF.Anesthesia,surgery,illness and Alzheimer's disease[J].Prog Neuropsychopharmacol Biol Psychiatry,2013,47:162-166.
[12]Terrando N,Eriksson LI,Ryu JK,et al.Resolving postoperative neuroinflammation and cognitive decline[J].Ann Neurol,2011,70(6):986-995.
[13]Akca O,Liem E,Suleman MI,et al.Effect of intra-operative end-tidalcarbon dioxide partial pressure on tissue oxygenation[J].Anaesthesia,2003,58(6):536-542.
[14]Sicard KM,Duong TQ.Effects of hypoxia,hyperoxia,and hypercapnia on baseline and stimulus-evoked BOLD,CBF,and CMRO 2 in spontaneously breathing animals[J].Neuroimage,2005,25(3):850-858.
[15]Jones M,Berwick J,Hewson-Stoate N,et al.The effect of hypercapnia on the neural and hemodynamic responses to somatosensory stimulation[J].Neuroimage,2005,27(3):609-623.
[16]Vannucci RC,Brucklacher RM,Vannucci SJ.Effect of carbon dioxide on cerebral metabolism during hypoxiaischemia in the immature rat[J].Pediatr Res,1997,42(1):24-29.
[17]Zappe AC,Uluda K,Oeltermann A,et al.The influence of moderate hypercapnia on neural activity in the anesthetized nonhuman primate[J].Cereb Cortex,2008,18(11):2666-2673.
[18]Salazar F,Donate M,Boget T,et al.Intraoperative warming and post-operative cognitive dysfunction after total knee replacement[J].Acta Anaesthesiol Scand,2011,55(2):216-222.