β-受体阻滞剂治疗高血压的临床疗效及安全性
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摘要
目的探讨β-受体阻滞剂治疗高血压的临床疗效及安全性。方法选取辽宁省本溪市明山区明山街道明山社区卫生服务中心2016年4月—2017年4月收治的高血压患者100例,随机分为对照组(n=50)和观察组(n=50)。对照组患者采用非洛地平片治疗,观察组患者采用β-受体阻滞剂治疗。比较两组患者的临床疗效及治疗前后舒张压、收缩压变化情况,并记录比较两组患者不良事件发生情况。结果观察组患者治疗总有效率高于对照组(P<0.05)。治疗前,两组患者收缩压、舒张压比较,差异无统计学意义(P>0.05);治疗后,观察组患者收缩压、舒张压低于对照组(P<0.05)。观察组患者不良反应发生率低于对照组(P<0.05)。结论采用β-受体阻滞剂治疗高血压具有疗效高、操作简单、用药安全性高的优势。
Objective To explore the clinical effect and safety of β-blockers in the treatment of hypertensiony.Methods A total of 100 cases of patients with hypertension were selected from April 2016 to April 2017 in Mingshan Community Health Service Center in Mingshan Street of Mingshan District,which were randomly divided into control group( n = 50) and observation group( n = 50). Control group was treated with felodipine tablets,observation group was treated with β-blockers. The clinical effect,systolic blood pressure and diastolic blood pressure before and after treatment were compared between the two groups,and the incidence of adverse reactions were observed. Results The total effective rate of observation group was significantly higher than that of control group( P < 0. 05). Before treatment,no siginificant differences of systolic blood pressure or diastolic blood pressure was found between the two groups( P > 0. 05); the systolic blood pressure and diastolic blood pressure of observation group were lower than control group( P < 0. 05). The incidence rate of adverse reactions of observation group was lower than control group( P < 0. 05). Conclusion β-blockers has advantages of higher clinical effect,simple handle and higher safety in the treatment of hypertension.
Objective To explore the clinical effect and safety of β-blockers in the treatment of hypertensiony.Methods A total of 100 cases of patients with hypertension were selected from April 2016 to April 2017 in Mingshan Community Health Service Center in Mingshan Street of Mingshan District,which were randomly divided into control group( n = 50) and observation group( n = 50). Control group was treated with felodipine tablets,observation group was treated with β-blockers. The clinical effect,systolic blood pressure and diastolic blood pressure before and after treatment were compared between the two groups,and the incidence of adverse reactions were observed. Results The total effective rate of observation group was significantly higher than that of control group( P < 0. 05). Before treatment,no siginificant differences of systolic blood pressure or diastolic blood pressure was found between the two groups( P > 0. 05); the systolic blood pressure and diastolic blood pressure of observation group were lower than control group( P < 0. 05). The incidence rate of adverse reactions of observation group was lower than control group( P < 0. 05). Conclusion β-blockers has advantages of higher clinical effect,simple handle and higher safety in the treatment of hypertension.
引文
[1]吴琼,陈建平,徐明霖,等.β-受体阻滞剂对老年性高血压患者血压水平不良反应及生活质量的影响[J].河北医学,2017,23(2):293-295.
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[9]何丽.β受体阻滞剂治疗高血压55例临床观察[J].内蒙古中医药,2012,31(23):48-49.DOI:10.3969/j.issn.1006-0979.2012.23.041.
[10]姚玉娟.β受体阻滞剂治疗高血压[J].国外医学(护理学分册),2001,18(9):425-426.DOI:10.3760/cma.j.issn.1673-4351.2001.09.016.
[11]施仲伟.β受体阻滞剂治疗高血压临床疗效再评价[J].医学研究杂志,2013,42(7):3-4.DOI:10.3969/j.issn.1673-548X.2013.07.002.
[12]朱敏.β受体阻滞剂治疗高血压62例临床观察[J].中国实用医药,2009,4(35):33-34.DOI:10.3969/j.issn.1673-7555.2009.35.019.
[2]孙浩,范小艳.血管紧张素受体阻滞剂治疗老年高血压患者轻度认知障碍的疗效[J].广东医学,2014,35(4):592-594.
[3]凌受毅,朱正芳,张伟国,等.血管紧张素受体拮抗剂联合β受体阻滞剂治疗中青年高血压的疗效[J].中西医结合心脑血管病杂志,2014,4(10):1216-1217.DOI:10.3969/jissn.16721349.2014.10.026.
[4]彭伊,叶远征,祖丽菲娅·木沙,等.β受体阻滞剂治疗高血压的疗效荟萃分析[J].中国基层医药,2014,86(16):2438-2441.DOI:10.3760/cma.jissn.1008-6706.2014.16.019.
[5]周云.β受体阻滞剂治疗高血压过程中对血脂的影响[J].中国基层医药,2012,19(16):2483-2484.
[6]孙娟.160例老年高血压患者应用β受体阻滞剂治疗的效果观察与分析[J].中外医疗,2014,34(35):78-79.DOI:10.3969/jissn.1674-0742.2014.35.038.
[7]刘祥.研究β-受体阻滞剂在高血压患者治疗中的应用价值[J].临床医药文献电子杂志,2015,2(19):3920.
[8]薛东莉.β受体阻滞剂在高血压治疗中的应用效果分析[J].世界临床医学,2016,10(21):56-57.
[9]何丽.β受体阻滞剂治疗高血压55例临床观察[J].内蒙古中医药,2012,31(23):48-49.DOI:10.3969/j.issn.1006-0979.2012.23.041.
[10]姚玉娟.β受体阻滞剂治疗高血压[J].国外医学(护理学分册),2001,18(9):425-426.DOI:10.3760/cma.j.issn.1673-4351.2001.09.016.
[11]施仲伟.β受体阻滞剂治疗高血压临床疗效再评价[J].医学研究杂志,2013,42(7):3-4.DOI:10.3969/j.issn.1673-548X.2013.07.002.
[12]朱敏.β受体阻滞剂治疗高血压62例临床观察[J].中国实用医药,2009,4(35):33-34.DOI:10.3969/j.issn.1673-7555.2009.35.019.