痛泻要方合四神丸加味论治溃疡性结肠炎验案二则
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摘要
溃疡性结肠炎是临床上常见病、多发病,主要以腹痛、腹泻、黏液脓血便、里急后重及全身症状为临床特征。发病率呈逐年上升趋势,因此越来越受到人们的关注与重视。临床上发现饮食不节、情志失调、脾胃受损、肾阳虚衰是该病的主要病因。病位主要在肠,病机复杂,以脾虚为本,而迁延反复发作、久治难愈,中医辨证多属于肝郁脾虚、脾肾两虚之证。因此在辨证的基础上,抑肝扶脾、温补脾肾是一条获取疗效的途径。采用痛泻要方合四神丸加味治疗溃疡性结肠炎取得了一定疗效,对溃疡性结肠炎的治疗思路有一定启发。
Ulcerative colitis is a chronic lesion of chronic rectum and colon of unknown cause. It is caused by varying degrees of abdominal pain,increased frequency of stools,often no formation,or watery stools,and even with mucus pus and blood. Symptoms of digestive diseases belong to the category of "diarrhea" and "dysentery" in the category of Chinese medicine. Unhealthy diet,emotional disorders,spleen and stomach damage,kidney yang deficiency is the main cause of this disease. Chronic relapsing patients,recurrent episodes,protracted and difficult to heal,TCM syndrome differentiation is mostly a syndrome of liver spleen deficiency and kidney deficiency. We have achieved a certain effect in the treatment of ulcerative colitis with Tongxie Yaofang Sishen Pill.
Ulcerative colitis is a chronic lesion of chronic rectum and colon of unknown cause. It is caused by varying degrees of abdominal pain,increased frequency of stools,often no formation,or watery stools,and even with mucus pus and blood. Symptoms of digestive diseases belong to the category of "diarrhea" and "dysentery" in the category of Chinese medicine. Unhealthy diet,emotional disorders,spleen and stomach damage,kidney yang deficiency is the main cause of this disease. Chronic relapsing patients,recurrent episodes,protracted and difficult to heal,TCM syndrome differentiation is mostly a syndrome of liver spleen deficiency and kidney deficiency. We have achieved a certain effect in the treatment of ulcerative colitis with Tongxie Yaofang Sishen Pill.
引文
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[2] DANESE S,RUDZISKI J,BRANDT W,etal.Tralokinumab for moderate-to-severe UC:a randomised double-blind,placebo-controlled,phase IIa study[J].Gut,2015(64):243-249.
[3] 郭建鹏.溃疡性结肠炎的中医药治疗研究进展[J].时珍国医国药,2006,17(8):1576-1577.
[4] 沙立娜,李楠,王艳梅.溃疡性结肠炎相关癌的回顾性探讨[J].标记免疫分析与临床,2014,21(2):145-147.
[5] 李强,于洋,徐鸿鹏,等.探讨溃疡性结肠炎复发的因素及临床研究进展[J].中国现代药物应用,2014,8(3):232-233.
[6] 孙健,高文艳,林一帆.溃疡性结肠炎病因和发病机制研究进展[J].辽宁中医药大学学报,2017,19(4):94-97.
[7] 李乾构.中医药治疗溃疡性结肠炎的思路[J].北京中医,2004,23(3):149-150.
[8] 张军,叶玉伟.中医药治疗溃疡性结肠炎研究进展概况[J].西部中医药,2013,26(12):150-152.
[9] 张晓婧,贾育新.祖国医学治疗溃疡性结肠炎研究进展[J].中医临床研究,2014,6(1):143-144.
[10] 谢灿果,丁丽君.重症肺炎患者应用美罗培南对临床疗效血清CRP及降钙素原的效果影响[J].大家健康(旬刊),2017,11(5):254-255.
[11] 王丽.溃疡性结肠炎病因及中医证治浅析[J].中医药学刊,2004,22(12):2278-2279.
[12] 樊慧丽,陈玉梅.溃疡性结肠炎发病机制和治疗进展[J].中国全科医学,2012,15(1B):228-230.
[13] 安惠霞,李治建,古丽娜·达吾提,等.地锦草的研究进展[J].时珍国医国药,2008,19(12):2866-2868.
[14] 张金炎.败酱草为主治疗慢性溃疡性结肠炎经验[J].中医杂志,2002,43(12):892.
[15] 李敏,梁超.中医对溃疡性结肠炎认识探源[J].中医药临床杂志,2006,18(6):622.
[16] 朱世恺,李敏.痛泻要方合参苓白术散治疗溃疡性结肠炎[J].内蒙古中医药,2012,22(3):30.