陈皮中总有机酸的电位滴定研究
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摘要
陈皮中含有多种功能型化合物,对人体消化系统和心血管系统均有较好的生物活性作用。总有机酸水平是衡量功能型化合物的重要指标之一。本文采用超声波法提取陈皮中的有机酸,通过电位滴定法结合单因素和正交试验优化了陈皮提取的最佳工艺条件为:乙醇体积分数为50%、料液比为1:20、超声时间60 min、超声提取温度为50℃,总有机酸含量达到12.76%。
There are many functional compounds in orange peel,which have good biological activities to human digestive and cardiovascular systems. The total organic acid level is one of the important indicators for measuring the functional compounds. In the present work,the organic acids in orange peel were extracted by using ultrasonic method. Through potentiometric titration combined with single factor and orthogonal tests,optimum extraction conditions of organic acids from the orange peel were obtained as ethanol concentration of50 %,solid-liquid ratio of 1:20,ultrasonic time of 60 min,and ultrasonic extraction temperature of 50 ℃. Under these conditions,the total organic acid content will reach up to 12.76 %.
There are many functional compounds in orange peel,which have good biological activities to human digestive and cardiovascular systems. The total organic acid level is one of the important indicators for measuring the functional compounds. In the present work,the organic acids in orange peel were extracted by using ultrasonic method. Through potentiometric titration combined with single factor and orthogonal tests,optimum extraction conditions of organic acids from the orange peel were obtained as ethanol concentration of50 %,solid-liquid ratio of 1:20,ultrasonic time of 60 min,and ultrasonic extraction temperature of 50 ℃. Under these conditions,the total organic acid content will reach up to 12.76 %.
引文
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[4]白燕,李晓玉,吴兆宇,等.陈皮的化学成分及药理作用研究[C]//中国药学会.2013年中国药学大会暨第十三届中国药师周论文集.北京:中国药学会,2013:4.
[5]郑小吉,詹晓如,王小平.陈皮研究进展[J].中国现代中药,2007(10):30-33.
[6]刘祥义.超声波提取元宝枫叶总黄酮方法研究[J].云南化工,2003(1):27-28.
[7]曾晖.鲜桔皮、陈皮、青皮中黄酮化合物的提取[J].中医药导报,2009,15(6):94-97.
[8]田维平,塔娜,李蜀眉,等.桔皮黄酮类化合物提取方法的研究[J].内蒙古农业大学学报(自然科学版),2002(3):66-68.
[9]官福兰,王如俊,王建华.陈皮及橙皮苷对离体肠管运动的影响[J].时珍国医国药,2002(2):65-67.