拉贝洛尔联合硫酸镁治疗子痫前期的效果观察
摘要
目的:探讨拉贝洛尔联合硫酸镁治疗子痫前期的效果。方法:将2015年12月-2017年12月200例子痫前期孕妇作为对象,依据数字表法分两组,各100例。对照组采用单一硫酸镁进行治疗,观察组则采用拉贝洛尔联合硫酸镁治疗。比较两组子痫前期治疗总有效率;24 h尿蛋白量与新生儿出生5 min的Apgar评分;用药前后产妇血压情况;分娩结局。结果:观察组子痫前期治疗总有效率高于对照组(P<0.05);观察组24 h尿蛋白量低于对照组,新生儿出生5 min的Apgar评分高于对照组(P<0.05);用药前两组血压情况差异无统计学意义(P>0.05),用药2 h观察组血压水平低于对照组(P<0.05)。观察组分娩结局优于对照组(P<0.05)。结论:拉贝洛尔联合硫酸镁治疗子痫前期的效果确切,可有效降低血压水平,改善分娩结局,减少24 h尿蛋白量,提高新生儿健康水平,值得推广。
引文
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[11]徐正芳.拉贝洛尔与硫酸镁对重症妊娠高血压产妇分娩结局的影响[J].当代医学,2015,21(16):139-140.
[12]殷万琴,格桑吉姆,尼玛卓嘎,等.拉贝洛尔联合硫酸镁治疗妊娠期高血压的临床效果探讨[J].世界临床医学,2017,11(4):106,110.
[2]Lewis G,Maxwell A P.Should women with diabetic nephropathy considering pregnancy continue ACE inhibitor or angiotensin II receptor blocker therapy until pregnancy is confirmed?[J].Diabetologia:Clinical and Experimental Diabetes and Metabolism:Organ of the European Association for the Study of Diabetes(EASD),2014,57(5):1082-1083.
[3]干胜利.拉贝洛尔治疗重度妊娠高血压综合征60例[J].中国药业,2013,22(9):28-29.
[4]徐闪,何俊明.羚角钩藤汤结合硫酸镁对子痫前期的防治效果[J].中国中医急症,2015,24(6):1118-1119.
[5]王晓临,肖建平.硫酸镁联合拉贝洛尔治疗早发型重度子痫前期效果观察[J].山东医药,2016,56(44):63-64.
[6]Swank M L,Caughey A B,Farinelli C K,et al.The impact of change in pregnancy body mass index on the development of gestational hypertensive disorders[J].Journal of Perinatology:Official Journal of the California Perinatal Association,2014,34(3):181-185.
[7]葛爱春.拉贝洛尔治疗妊娠高血压45例临床疗效及对分娩结局的影响[J].陕西医学杂志,2013,42(7):897-898.
[8]符泽美,王爱丽,裴雄越,等.硫酸镁联合硝苯地平或拉贝洛尔治疗妊娠高血压疗效比较[J].海南医学,2016,27(14):2346-2348.
[9]Addario L,Tritto G,CavagliàE,et al.Gastric variceal bleeding from segmentary idiopathic splenic vein stenosis with left-sided portal hypertension:An unappreciated complication of pregnancy[J].Hepatology Research:the Official Journal of the Japan Society of Hepatology,2014,44(2):246-249.
[10]Salazar-Vega J L,Levin G,Sanso G,et al.Pheochromocytoma associated with pregnancy:Unexpected favourable outcome in patients diagnosed after delivery[J].Journal of Hypertension,2014,32(7):1458-1463.
[11]徐正芳.拉贝洛尔与硫酸镁对重症妊娠高血压产妇分娩结局的影响[J].当代医学,2015,21(16):139-140.
[12]殷万琴,格桑吉姆,尼玛卓嘎,等.拉贝洛尔联合硫酸镁治疗妊娠期高血压的临床效果探讨[J].世界临床医学,2017,11(4):106,110.