以视乳头水肿为首发症状的SLE一例
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摘要
SLE起病隐匿,发病形式多样,除面部红斑等典型表现外,可以全身各系统损害为首发表现,本文报道1例以视乳头水肿为首发症状的SLE诊断经过。该患者以视乳头水肿为首发症状,颅脑MRI未见异常,短期呈现多系统损害,最终行免疫学相关检查诊断SLE,后经肾上腺皮质激素治疗病情控制。该例的诊治提示,临床工作者应提高对免疫疾病的认识,早期诊断、早期治疗,对改善SLE患者的预后至关重要。
The onset of systemic lupus erythematosus(SLE) is elusive and diverse. Besides typical facial erythema, systemic damages can occur as the first symptoms of SLE. In this article, the diagnosis and treatment of one SLE patients presenting the edema of optic papilla as the initial symptom were reported. The cerebral MRI revealed no abnormality. The patient presented with multi-system damages in the short term. The patient was eventually diagnosed with SLE by immune examination. The physical condition remained stable after hormone therapy. This case prompts that clinicians should deepen the understanding of immune diseases. Early diagnosis and treatment play a pivotal role in improving the clinical prognosis of SLE patients.
The onset of systemic lupus erythematosus(SLE) is elusive and diverse. Besides typical facial erythema, systemic damages can occur as the first symptoms of SLE. In this article, the diagnosis and treatment of one SLE patients presenting the edema of optic papilla as the initial symptom were reported. The cerebral MRI revealed no abnormality. The patient presented with multi-system damages in the short term. The patient was eventually diagnosed with SLE by immune examination. The physical condition remained stable after hormone therapy. This case prompts that clinicians should deepen the understanding of immune diseases. Early diagnosis and treatment play a pivotal role in improving the clinical prognosis of SLE patients.
引文
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[5]王文吉.视盘水肿都是视盘炎吗.中国眼耳鼻喉科杂志,2013,13(4):208-210.
[6]程杰,熊飞,郝晓林,于璐,凌宇. SLE伴视网膜病变的临床特征分析.国际眼科杂志,2018,18(5):941-944.
[7]陈乔,聂尚武,王晓琴,陈盼.系统性红斑狼疮合并视网膜微血管阻塞的临床观察.中国医药导报,2016,13(2):125-128.
[8]沈姗,柴华旗.以视神经炎为首发症状的系统性红斑狼疮.江苏医药,2013,39(11):1355-1356.
[9]杜虹,陆慧琴,戴荣平.系统性红斑狼疮眼底病变评估和分型.眼科新进展,2017,37(8):766-769.
[10]陈乔,聂尚武,王晓琴,陈盼.合并视网膜大血管阻塞的系统性红斑狼疮的临床观察.国际眼科杂志,2015,15(12):2167-2170.
[11]张成成,张立,叶应嘉,陈毕峰.系统性红斑狼疮所致眼底病变1例.中华眼底病杂志,2012,12(1):193-194.
[2]Rai R, Chauhan SK, Singh VV, Rai M, Rai G. RNA-seq analysis reveals unique transcriptome signatures in systemic lupus erythematosus patients with distinct autoantibody specificities. PLoS One,2016,11(11):e0166312.
[3]田国红,陈倩.视盘水肿的鉴别及病因分析.中国眼耳鼻喉科杂志,2017,17(5):378-381.
[4]李波,李洵桦.红细胞数量异常继发以视神经损害为首的颅内血管病变二例及文献复习.新医学,2013,44(8):574-579.
[5]王文吉.视盘水肿都是视盘炎吗.中国眼耳鼻喉科杂志,2013,13(4):208-210.
[6]程杰,熊飞,郝晓林,于璐,凌宇. SLE伴视网膜病变的临床特征分析.国际眼科杂志,2018,18(5):941-944.
[7]陈乔,聂尚武,王晓琴,陈盼.系统性红斑狼疮合并视网膜微血管阻塞的临床观察.中国医药导报,2016,13(2):125-128.
[8]沈姗,柴华旗.以视神经炎为首发症状的系统性红斑狼疮.江苏医药,2013,39(11):1355-1356.
[9]杜虹,陆慧琴,戴荣平.系统性红斑狼疮眼底病变评估和分型.眼科新进展,2017,37(8):766-769.
[10]陈乔,聂尚武,王晓琴,陈盼.合并视网膜大血管阻塞的系统性红斑狼疮的临床观察.国际眼科杂志,2015,15(12):2167-2170.
[11]张成成,张立,叶应嘉,陈毕峰.系统性红斑狼疮所致眼底病变1例.中华眼底病杂志,2012,12(1):193-194.