丰隆穴位注射异丙嗪治疗痰浊中阻型后循环缺血性眩晕疗效观察
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摘要
目的观察丰隆穴位注射异丙嗪治疗痰浊中阻型后循环缺血性眩晕的临床疗效。方法将62例痰浊中阻型后循环缺血性眩晕患者随机分为治疗组和对照组,每组31例。两组均接受长春西汀注射液静脉滴注治疗,治疗组在此基础上采用丰隆穴位注射异丙嗪注射液治疗,对照组在此基础上采用臀部肌肉注射异丙嗪注射液治疗。观察两组治疗前后中医证候评分、眩晕障碍量表(DHI)评分的变化情况,并比较两组临床疗效。结果两组治疗后中医证候评分及DHI评分与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗后中医证候评分及DHI评分与对照组比较,差异均具有统计学意义(P<0.05)。治疗组总有效率为93.5%,对照组为80.6%,两组比较差异具有统计学意义(P<0.05)。结论丰隆穴位注射异丙嗪是一种治疗痰浊中阻型后循环缺血性眩晕的有效方法。
Objective To observe the clinical efficacy of acupoint injection at Fenglong(ST 40) with Promethazine in treating posterior circulation ischemic vertigo(PCIV) due to turbid phlegm obstructing the middle. Method Sixty-two patients with PCIV due to turbid phlegm obstructing the middle were randomized into a treatment group and a control group, 31 cases each. The two groups both received intravenous infusion of Vinpocetine injection, based on which, the treatment group was intervened by injection at Fenglong(ST 40) with Promethazine, while the control group was given gluteal intramuscular injection of Promethazine. The traditional Chinese medicine(TCM) syndrome score and Dizziness Handicap Inventory(DHI) were observed for the two groups before and after the treatment, and the clinical efficacies were also compared. Result The TCM syndrome and DHI scores were significant changed after the intervention in both groups(P<0.05). After the treatment, the TCM syndrome and DHI scores in the treatment group were significantly different from those in the control group(P<0.05). The total effective rate was 93.5% in the treatment group versus 80.6% in the control group, and the between-group difference was statistically significant(P<0.05). Conclusion Injection at Fenglong(ST 40) with Promethazine is an effective method in treating PCIV due to turbid phlegm obstructing the middle.
Objective To observe the clinical efficacy of acupoint injection at Fenglong(ST 40) with Promethazine in treating posterior circulation ischemic vertigo(PCIV) due to turbid phlegm obstructing the middle. Method Sixty-two patients with PCIV due to turbid phlegm obstructing the middle were randomized into a treatment group and a control group, 31 cases each. The two groups both received intravenous infusion of Vinpocetine injection, based on which, the treatment group was intervened by injection at Fenglong(ST 40) with Promethazine, while the control group was given gluteal intramuscular injection of Promethazine. The traditional Chinese medicine(TCM) syndrome score and Dizziness Handicap Inventory(DHI) were observed for the two groups before and after the treatment, and the clinical efficacies were also compared. Result The TCM syndrome and DHI scores were significant changed after the intervention in both groups(P<0.05). After the treatment, the TCM syndrome and DHI scores in the treatment group were significantly different from those in the control group(P<0.05). The total effective rate was 93.5% in the treatment group versus 80.6% in the control group, and the between-group difference was statistically significant(P<0.05). Conclusion Injection at Fenglong(ST 40) with Promethazine is an effective method in treating PCIV due to turbid phlegm obstructing the middle.
引文
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[31]周从民.异丙嗪穴位注射治疗颈性眩晕临床分析[J].中医药临床杂志,2013,25(9):772-773.
[32]白洪蕊.前列地尔联合长春西汀在后循环缺血性眩晕中的疗效观察[J].天津药学,2014,26(3):44-45.
[2]邱峰,戚晓昆.神经内科门诊367例有眩晕主诉患者的病因分析[J].中华内科杂志,2012,51(5):350-352.
[3]刘兰,刘筠,许亮.后循环缺血性眩晕患者椎-基底动脉形态学改变[J].中国脑血管病杂志,2016,13(2):62-66,99.
[4]吴勉华,王新月.中医内科学[M].北京:中国中医药出版社,2014:267.
[5]郑筱萸.中药新药临床研究指导原则[S].北京:中国医药科技出版社,2002:207-209,210-214.
[6]Peng C,Wang X,He C,et al.The value of the uc N13-P15 interpeak latency predicted acute posterior circulation ischemia and the chronic outcome[J].J Clin Neurophysiol,2014,31(5):462-468.
[7]Searls DE,Pazdera L,Korbel E,et al.Symptoms and signs of posterior circulation ischemia in the new England medical center posterior circulation registry[J].Arch Neurol,2012,69(3):346-351.
[8]Chen R,Su R,Deng M,et al.A Posterior Circulation Ischemia Risk Score System to Assist the Diagnosis of Dizziness[J].J Stroke Cerebrovasc Dis,2018,27(2):506-512.
[9]Harteveld AA,van der Kolk AG,van der Worp HB,et al.Detecting Intracranial Vessel Wall Lesions With 7TMagnetic Resonance Imaging:Patients With Posterior Circulation Ischemia Versus Healthy Controls[J].Stroke,2017,48(9):2601-2604.
[10]栾岚,徐世亮,岳超,等.TCD联合低剂量双源CTA筛查对椎基底动脉易损斑块分布规律及后循环缺血的相关性分析[J].中国地方病防治杂志,2017,32(6):622,625.
[11]王俊波,郭兴华.磁共振血管造影应用于后循环缺血性眩晕诊断中的价值研究[J].中国实用医刊,2017,44(7):74-77.
[12]王淑敏,王伟,宋义周,等.应用颅脑CT血管成像联合CT灌注成像诊断后循环缺血的临床价值分析[J].当代医药论丛,2014,12(18):54-56.
[13]于峰.氟桂利嗪联合银杏达莫治疗老年后循环缺血性眩晕的疗效[J].中国老年学杂志,2012,32(6):1172-1173.
[14]王傈,柳太云.后循环缺血病因与诊断的研究进展[J].临床合理用药,2016,9(10):176-177.
[15]杨燕妮,杨思进.中医药治疗后循环缺血性眩晕进展[J].内蒙古中医药,2017,36(1):124-125.
[16]周艳红,纪春玲.中医治疗后循环缺血性眩晕[J].中国医药指南,2015,13(32):193-194.
[17]周路,胡跃强,贺启荣.中医药治疗后循环缺血性眩晕的临床研究进展[J].广西中医药大学学报,2017,20(2):74-77.
[18]李翠蓉,夏炳兰,杨进.彩色多普勒超声检查椎动脉发育不良在后循环缺血中的应用价值[J].中国血液流变学杂志,2012,22(4):710-712.
[19]刘红梅.眩晕症的中医证候及多元分析初步研究[D].中国中医科学院,2006.
[20]周路,赵利华,贺启荣,等.壮医针刺对后循环缺血性眩晕患者脑干听觉诱发电位的影响[J].上海针灸杂志,2016,35(9):1062-1064.
[21]刘丰,韩巨.后循环缺血的诊断和急性期治疗的研究进展[J].中风与神经疾病杂志,2016,33(11):1048-1050.
[22]杨燕妮,杨思进.中医药治疗后循环缺血性眩晕进展[J].内蒙古中医药,2017,36(1):124-125.
[23]康志强,陈华德.穴位注射作用效应及机制的研究进展[J].浙江中西医结合杂志,2010,20(2):119-120.
[24]赵永娇,马红英,蔡德光.穴位埋线及穴位注射的临床和机制研究进展[J].现代中西医结合杂志,2013,22(7):784-787.
[25]许晓康,贾春生,王建岭,等.基于数据挖掘技术的穴位注射疗法效应特点研究[J].针刺研究,2012,37(2):155-160.
[26]李孟汉,郭义.穴位注射研究进展与展望[J].针灸临床杂志,2010,26(10):69-72.
[27]解秸萍,李晓泓,李蔚,等.丰隆穴化痰作用及机制探讨[J].针灸临床杂志,2006,22(1):1-4.
[28]黄思仪.针刺丰隆足三里对痰湿体质人群中医体质影响临床研究[J].云南中医中药杂志,2016,37(4):43-44.
[29]张海涛.盐酸异丙嗪联合天麻素、血塞通治疗后循环缺血性眩晕疗效观察[J].大家健康(中旬版),2014,8(1):224-225.
[30]胡运朋,吴丰学,鲁婷.马来酸桂哌齐特联合盐酸异丙嗪治疗急诊眩晕症对患者症状改善及生活质量的影响[J].中国医学前沿杂志(电子版),2015,7(10):87-89.
[31]周从民.异丙嗪穴位注射治疗颈性眩晕临床分析[J].中医药临床杂志,2013,25(9):772-773.
[32]白洪蕊.前列地尔联合长春西汀在后循环缺血性眩晕中的疗效观察[J].天津药学,2014,26(3):44-45.