上海市松江区佘山镇常住人口肾功能损伤情况及其相关因素
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摘要
【目的】了解上海地区常住人口的肾功能损伤情况,并分析相关影响因素,为当地肾损伤防治提供参考。【方法】采用整群随机抽样的方法选取松江区佘山镇20~74岁的常住居民,对其开展问卷调查、体格检查及实验室检测,并分析肾功能损伤患病的影响因素。【结果】本次共调查上海地区常住居民5 668名,慢性肾功能损伤患病率为19.51%,多因素logistic回归分析显示女性(OR=4.36,95%CI:3.45-5.50)、高年龄(OR=2.85,95%CI:2.14~3.79)、吸烟史(OR=1.28,95%CI:0.96~1.71)及中心性肥胖(OR=1.42,95%CI:1.19~1.69)是肾功能损伤发病的独立相关因素。【结论】上海地区常住居民的肾功能损伤患病率较高,应进一步关注高危人群,加强完善人群肾损伤疾病的防治。
[Objective]In order to ascertain the situation of renal impairment among permanent residents in Shanghai and analyze the related risk factors,providing the reference to the prevention and treatment of renal impairment. [Methods]A randomized cluster sampling method was used to recruit the residents aged20-74 in Sheshan Town,Songjiang District. Questionnaire interview,physical examination and laboratory test were conducted, and the influencing factors of renal injury analyzed. [Results] A total of 6 831 residents were surveyed in Shanghai. The prevalence of chronic renal impairment was 19. 51%. Multivariate logistic regression analysis showed that male( OR = 4. 36,95% CI: 3. 45-5. 50),older population( OR = 2. 85,95% CI: 2. 14-3. 79),history of tobacco use( OR = 1. 28,95% CI: 0. 96-1. 71) and central obesity( OR = 1. 42,95% CI: 1. 19-1. 69) were the independent risk factors of renal impairment.[Conclusion]The prevalence of renal impairment is relatively high among Shanghai permanent residents,so we should further strengthen the prevention and treatment of renal impairment in the population,focusing on high-risk groups in particular.
[Objective]In order to ascertain the situation of renal impairment among permanent residents in Shanghai and analyze the related risk factors,providing the reference to the prevention and treatment of renal impairment. [Methods]A randomized cluster sampling method was used to recruit the residents aged20-74 in Sheshan Town,Songjiang District. Questionnaire interview,physical examination and laboratory test were conducted, and the influencing factors of renal injury analyzed. [Results] A total of 6 831 residents were surveyed in Shanghai. The prevalence of chronic renal impairment was 19. 51%. Multivariate logistic regression analysis showed that male( OR = 4. 36,95% CI: 3. 45-5. 50),older population( OR = 2. 85,95% CI: 2. 14-3. 79),history of tobacco use( OR = 1. 28,95% CI: 0. 96-1. 71) and central obesity( OR = 1. 42,95% CI: 1. 19-1. 69) were the independent risk factors of renal impairment.[Conclusion]The prevalence of renal impairment is relatively high among Shanghai permanent residents,so we should further strengthen the prevention and treatment of renal impairment in the population,focusing on high-risk groups in particular.
引文
[1]LEVIN A,TONELLI M,BONVENTRE J,et al.Global kidney health 2017 and beyond:a roadmap for closing gaps in care,research,and policy[J].Lancet,2017,390(10105):1888-1917.
[2]ZHANG LX,WANG F,WANG L,et al.Prevalence of chronic kidney disease in China:a cross-sectional survey[J].Lancet,2012,379(9818):815-822.
[3]程莹,李宁娜,游志清,等.三种CKD-EPI公式与改良MDRD公式诊断糖尿病肾病一致性分析[J].中国全科医学,2016,19(29):3584-3588.
[4]张艳,傅辰生,王姣锋,等.肾小球滤过率评估公式在老年慢性肾脏病患者中的适用性研究[J].中华老年医学杂志,2014,33(6):600-605.
[5]王晓菁,陈海平.慢性肾脏病定义及分期系统修订的进展——2012-KDIGO慢性肾脏病临床管理实践指南解读[J].中华老年多器官疾病杂志,2014,13(5):396-400.
[6]陈香美,孙雪峰.共同参与有效防治老年肾脏病[J].中华医学信息导报,2014,29(5):14.
[7]陈香美,孙雪峰,蔡广研.我国慢性肾脏病防治的公共健康政策思考[J].中华医学杂志,2014,94(4):241-毜243.
[8]顾乡,方向华.老年人慢性肾脏病诊断标准和分期以及流行病学研究现状[J].中华老年医学杂志,2016,35(5):556-559.
[9]赵慧,李晓玫,王玉.老年人慢性肾脏病研究现状[J].中华老年医学杂志,2014,33(2):214-218.
[10]刘晓琳,周弋,阮晓楠,等.上海市浦东新区慢性肾病流行情况及其危险因素研究[J].中国全科医学,2016,19(30):3742-3750.
[11]郭涛.代谢综合征及其相关性疾病[J].中国保健营养,2016,26(21):114.
[12]杨金友,张巧玲,孙莉莉,等.慢性肾功能衰竭影响因素的病例对照研究[J].中国全科医学,2015,18(4):413-416.
[13]FAYE M,LEMRABOTT A T,CISSM M,et al.Prevalence and risk factors of chronic kidney disease in an African semi-urban area:results from a cross-sectional survey in Gueoul,Senegal[J].Saudi J Kidney Dis Transpl,2017,28(6):1389-1396.
[14]SHEN YJ,CAI RR,SUN J,et al.Diabetes mellitus as a risk factor for incident chronic kidney disease and end-stage renal disease in women compared with men:a systematic review and meta-analysis[J].Endocrine,2017,55(1):66-76.
[15]KOMENDAREK-KOWALSKA M.The assessment of renal function in patients with newly diagnosed hypertension-the role of hyperuricemia as a risk factor for chronic kidney disease-preliminary study[J].Pol Merkur Lekarski,2017,42(251):193-196.
[16]张丽红,于倩倩,范伟峰,等.上海闵行地区城乡老年人慢性肾脏病患病率及其相关因素的对比[J].中华肾脏病杂志,2017,33(5):356-362.
[17]朱美英,陆殷昊,程旻娜,等.社区中老年糖尿病患者三种指标达标率及与血清肌酐和尿素氮的关系[J].上海预防医学,2015,27(11):660-664.
[18]宋锐,蔡惠勇,徐虹霞,等.社区干预在糖尿病肾病患者中的实施效果观察[J].上海预防医学,2016,28(1):37-40.
[19]毛永辉.慢性肾脏病患者的健康生活方式[J].中华肾病研究电子杂志,2017,6(3):109-113.
[2]ZHANG LX,WANG F,WANG L,et al.Prevalence of chronic kidney disease in China:a cross-sectional survey[J].Lancet,2012,379(9818):815-822.
[3]程莹,李宁娜,游志清,等.三种CKD-EPI公式与改良MDRD公式诊断糖尿病肾病一致性分析[J].中国全科医学,2016,19(29):3584-3588.
[4]张艳,傅辰生,王姣锋,等.肾小球滤过率评估公式在老年慢性肾脏病患者中的适用性研究[J].中华老年医学杂志,2014,33(6):600-605.
[5]王晓菁,陈海平.慢性肾脏病定义及分期系统修订的进展——2012-KDIGO慢性肾脏病临床管理实践指南解读[J].中华老年多器官疾病杂志,2014,13(5):396-400.
[6]陈香美,孙雪峰.共同参与有效防治老年肾脏病[J].中华医学信息导报,2014,29(5):14.
[7]陈香美,孙雪峰,蔡广研.我国慢性肾脏病防治的公共健康政策思考[J].中华医学杂志,2014,94(4):241-毜243.
[8]顾乡,方向华.老年人慢性肾脏病诊断标准和分期以及流行病学研究现状[J].中华老年医学杂志,2016,35(5):556-559.
[9]赵慧,李晓玫,王玉.老年人慢性肾脏病研究现状[J].中华老年医学杂志,2014,33(2):214-218.
[10]刘晓琳,周弋,阮晓楠,等.上海市浦东新区慢性肾病流行情况及其危险因素研究[J].中国全科医学,2016,19(30):3742-3750.
[11]郭涛.代谢综合征及其相关性疾病[J].中国保健营养,2016,26(21):114.
[12]杨金友,张巧玲,孙莉莉,等.慢性肾功能衰竭影响因素的病例对照研究[J].中国全科医学,2015,18(4):413-416.
[13]FAYE M,LEMRABOTT A T,CISSM M,et al.Prevalence and risk factors of chronic kidney disease in an African semi-urban area:results from a cross-sectional survey in Gueoul,Senegal[J].Saudi J Kidney Dis Transpl,2017,28(6):1389-1396.
[14]SHEN YJ,CAI RR,SUN J,et al.Diabetes mellitus as a risk factor for incident chronic kidney disease and end-stage renal disease in women compared with men:a systematic review and meta-analysis[J].Endocrine,2017,55(1):66-76.
[15]KOMENDAREK-KOWALSKA M.The assessment of renal function in patients with newly diagnosed hypertension-the role of hyperuricemia as a risk factor for chronic kidney disease-preliminary study[J].Pol Merkur Lekarski,2017,42(251):193-196.
[16]张丽红,于倩倩,范伟峰,等.上海闵行地区城乡老年人慢性肾脏病患病率及其相关因素的对比[J].中华肾脏病杂志,2017,33(5):356-362.
[17]朱美英,陆殷昊,程旻娜,等.社区中老年糖尿病患者三种指标达标率及与血清肌酐和尿素氮的关系[J].上海预防医学,2015,27(11):660-664.
[18]宋锐,蔡惠勇,徐虹霞,等.社区干预在糖尿病肾病患者中的实施效果观察[J].上海预防医学,2016,28(1):37-40.
[19]毛永辉.慢性肾脏病患者的健康生活方式[J].中华肾病研究电子杂志,2017,6(3):109-113.