运动训练对中老年2型糖尿病病人干预效果的系统评价
摘要
[目的]系统评价有氧运动联合抗阻训练对中老年2型糖尿病病人的干预效果。[方法]计算机检索PubMed、EM base、The Cochrane Library、JBI、Sino Med、CNKI和Wan Fang数据库,查找有关联合运动干预2型糖尿病的随机对照试验(RCT),进行资料提取和质量评价,采用Rev Man 5.3软件进行Meta分析。[结果]纳入12个RCT,共687例中老年2型糖尿病病人。Meta分析结果显示:有氧运动联合抗阻训练在改善糖化血红蛋白方面具有显著作用,且干预组血脂、摄氧量改善均优于对照组。但对血压的改变两者无明显差异。[结论]联合运动可改善中老年糖尿病病人血糖控制、血脂和心肺功能。
引文
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[13] LIU Y,LIU S X,CAI Y,et al.Effects of combined aerobic and resistance training on the glycolipid metabolism and inflammation levels in type 2 diabetes mellitus[J].J Phys Ther Sci,2015,27(7):2365-2371.
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[15] SPARKS L M,JOHANNSEN N M,CHURCH T S,et al.Nine months of combined training improves ex vivo skeletal muscle metabolism in individuals with type 2 diabetes[J].J Clin Endocrinol Metab,2013,98(4):1694-1702.
[16] SWIFT D L,JOHANNSEN N M,EARNEST C P,et al.Effect of exercise training modality on c-reactive protein in type 2 diabetes[J].Med Sci Sports Exerc,2012,44(6):1028-1034.
[17] SIGAL R J,KENNY G P,BOULE N G,et al.Effects of aerobic training,resistance training,or both on glycemic control in type 2 diabetes:a randomized trial[J].Ann Intern Med,2007,147(6):357-369.
[18] CUFF D J,MENEILLY G S,MARTIN A,et al.Effective exercise modality to reduce insulin resistance in women with type 2 diabetes[J].Diabetes Care,2003,26(11):2977-2982.
[19] TAN S,LI W,WANG J.Effects of six months of combined aerobic and resistance training for elderly patients with a long history of type 2 diabetes[J].J Sports Sci Med,2012,11(3):495-501.
[20] GRONTVED A,RIED-LARSEN M,EKELUND U,et al.Independent and combined association of muscle strength and cardiorespiratory fitness in youth with insulin resistance and beta-cell function in young adulthood:the European Youth Heart Study[J].Diabetes Care,2013,36(9):2575-2581.
[2] 中华医学会糖尿病学会.中国2型糖尿病防治指南(2017年版)[J].中华糖尿病杂志,2018,10(1):2-67.
[3] BOHM A,WEIGERT C,STAIGER H,et al.Exercise and diabetes:relevance and causes for response variability[J].Endocrine,2016,51(3):390-401.
[4] LEE J,KIM D,KIM C.Resistance training for glycemic control,muscular strength,and lean body mass in old type 2 diabetic patients:a meta-analysis[J].Diabetes Ther,2017,8(3):459-473.
[5] GRACE A,CHAN E,GIALLARUIA F,et al.Clinical outcomes and glycaemic responses to different aerobic exercise training intensities in type II diabetes:a systematic review and meta-analysis[J].Cardiovasc Diabetol,2017,16(1):37.
[6] HARRISON A L,SHIELDS N,TAYLOR N F,et al.Exercise improves glycaemic control in women diagnosed with gestational diabetes mellitus:a systematic review[J].J Physiother,2016,62(4):188-196.
[7] 侯云英,汪小华,李伟,等.Meta分析运动训练与有氧运动对2型糖尿病患者血糖控制及并发症危险因素的影响[J].中国实用护理杂志,2013,29(5):52-55.
[8] 周加峰,叶新新.中等强度有氧和抗阻运动对老年Ⅱ型糖尿病患者血液生化指标和心肺功能的影响[J].北京体育大学学报,2011(03):64-66.
[9] CHURCH T S,BLAIR S N,COCREHAM S,et al.Effects of aerobic and resistance training on hemoglobin a1cl Levels in patients with type 2 diabetes[J].JAMA,2010,304(20):2253.
[10] BALDUCCI S,ZANUSO S,NICOLUCCI A,et al.Anti-inflammatory effect of exercise training in subjects with type 2 diabetes and the metabolic syndrome is dependent on exercise modalities and independent of weight loss[J].Nutr Metab Carbiovasc Dis,2010,20(8):608-617.
[11] EARNEST C P,JOHANNSEN N M,SWIFT D L,et al.Aerobic and strength training in concomitant metabolic syndrome and type 2 diabetes[J].Med Sci Sports Exerc,2014,46(7):1293-1301.
[12] JORGE M L M P,DE OLIVEIRA V N,RESENDE N M,et al.The effects of aerobic,resistance,and combined exercise on metabolic control,inflammatory markers,adipocytokines,and muscle insulin signaling in patients with type 2 diabetes mellitus[J].Metabolism,2011,60(9):1244-1252.
[13] LIU Y,LIU S X,CAI Y,et al.Effects of combined aerobic and resistance training on the glycolipid metabolism and inflammation levels in type 2 diabetes mellitus[J].J Phys Ther Sci,2015,27(7):2365-2371.
[14] LAMBERS S,VAN LAETHEM C,VAN ACKER K,et al.Influence of combined exercise training on indices of obesity,diabetes and cardiovascular risk in type 2 diabetes patients[J].Clin.Rehabil,2008,22(6):483-492.
[15] SPARKS L M,JOHANNSEN N M,CHURCH T S,et al.Nine months of combined training improves ex vivo skeletal muscle metabolism in individuals with type 2 diabetes[J].J Clin Endocrinol Metab,2013,98(4):1694-1702.
[16] SWIFT D L,JOHANNSEN N M,EARNEST C P,et al.Effect of exercise training modality on c-reactive protein in type 2 diabetes[J].Med Sci Sports Exerc,2012,44(6):1028-1034.
[17] SIGAL R J,KENNY G P,BOULE N G,et al.Effects of aerobic training,resistance training,or both on glycemic control in type 2 diabetes:a randomized trial[J].Ann Intern Med,2007,147(6):357-369.
[18] CUFF D J,MENEILLY G S,MARTIN A,et al.Effective exercise modality to reduce insulin resistance in women with type 2 diabetes[J].Diabetes Care,2003,26(11):2977-2982.
[19] TAN S,LI W,WANG J.Effects of six months of combined aerobic and resistance training for elderly patients with a long history of type 2 diabetes[J].J Sports Sci Med,2012,11(3):495-501.
[20] GRONTVED A,RIED-LARSEN M,EKELUND U,et al.Independent and combined association of muscle strength and cardiorespiratory fitness in youth with insulin resistance and beta-cell function in young adulthood:the European Youth Heart Study[J].Diabetes Care,2013,36(9):2575-2581.