不同部位骨折患者血浆D-二聚体水平分析
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摘要
目的:探讨不同部位骨折患者血浆D-二聚体水平。方法:选择855例骨折患者,采集静脉血,对血浆D-二聚体水平进行测定,对下肢深静脉血栓形成的发生情况进行判断。结果:多发伤骨折患者的血浆D-二聚体水平最高,其次则为股骨骨折和胫腓骨骨折;骨折部位不同,患者血浆D-二聚体水平差异具有统计学意义(P<0.05)。855例患者中,85例患者发生下肢深静脉血栓形成,发生率为9.9%。而血浆D-二聚体水平与下肢深静脉血栓形成发生率呈正相关。结论:骨折损伤程度、骨折部位与血浆D-二聚体水平之间的联系非常密切,同时血浆D-二聚体水平与下肢深静脉血栓形成的发生率存在显著相关性。
Objective:To investigate the plasma D-dimer level in patients with fractures in different locations.Methods: 855 fracture patients were selected,Venous blood was collected and plasma D-dimer level was measured,deep venous thrombosis in lower extremity were judged. Results:Multiple fractures patients with highest level of plasma D-dimer,the second was femoral fracture and tibia and fibula fracture;there were also significant differences in plasma D-dimer levels among patients with different fracture sites(P<0.05); In 855 fracture patients,85 patients with deep venous thrombosis of lower extremity,the incidence was 9.9%.The plasma D-dimer level was positively correlated with the incidence of deep venous thrombosis in the lower extremities.Conclusion:The degree of fracture injury,the location of fracture and the level of plasma D-dimer are closely related,at the same time, there was a significant correlation between plasma D-dimer level and the incidence of deep venous thrombosis in lower extremities.
Objective:To investigate the plasma D-dimer level in patients with fractures in different locations.Methods: 855 fracture patients were selected,Venous blood was collected and plasma D-dimer level was measured,deep venous thrombosis in lower extremity were judged. Results:Multiple fractures patients with highest level of plasma D-dimer,the second was femoral fracture and tibia and fibula fracture;there were also significant differences in plasma D-dimer levels among patients with different fracture sites(P<0.05); In 855 fracture patients,85 patients with deep venous thrombosis of lower extremity,the incidence was 9.9%.The plasma D-dimer level was positively correlated with the incidence of deep venous thrombosis in the lower extremities.Conclusion:The degree of fracture injury,the location of fracture and the level of plasma D-dimer are closely related,at the same time, there was a significant correlation between plasma D-dimer level and the incidence of deep venous thrombosis in lower extremities.
引文
[1]田广,刘敏.创伤患者血浆D-二聚体、纤维蛋白原与骨折部位及创伤程度的相关性研究[J].中国社区医师,2018,34(22):102~103.
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[8]P.R.Chithira,Teny Theresa John.Defect and dopant induced room temperature ferromagnetism in Ni doped ZnO nanoparticles[J].Journal of Alloys and Compounds,2018:766.
[9]Sanchayita Nag,Anirban Roychowdhury,Dipankar Das,et al.Structural and magnetic properties of erbium(Er 3+)doped nickel zinc ferrite prepared by sol-gel auto-combustion method[J].Journal of Magnetism and Magnetic Materials,2018:466.
[2]陈军号.血浆D-二聚体测定联合超声检查对诊断髋部骨折患者下肢深静脉血栓的价值[J].检验医学与临床,2018,15(2):245~247.
[3]张年春,朱建华,罗文峰,等.闭合性骨折创伤患者血浆D-二聚体和纤维蛋白原水平及与创伤程度的相关性研究[J].解放军医药杂志,2017,29(4):82~84.
[4]贾军岩.分析不同骨折创伤患者的血浆D-二聚体水平[J].中国医药指南,2016,14(36):67.
[5]徐荣华,陈静,张宁.股骨颈骨折患者血浆D-二聚体的变化及其临床意义[J].现代医学,2015,43(9):1104~1106.
[6]吴广忠.血浆D-二聚体和血清超敏C反应蛋白在骨折患者术后病情评估中的应用[J].实验与检验医学,2015,33(4):478~479.
[7]任庆远.骨折患者血浆D-二聚体水平升高影响因素探讨[J].临床血液学杂志,2015,28(1):132~134.
[8]P.R.Chithira,Teny Theresa John.Defect and dopant induced room temperature ferromagnetism in Ni doped ZnO nanoparticles[J].Journal of Alloys and Compounds,2018:766.
[9]Sanchayita Nag,Anirban Roychowdhury,Dipankar Das,et al.Structural and magnetic properties of erbium(Er 3+)doped nickel zinc ferrite prepared by sol-gel auto-combustion method[J].Journal of Magnetism and Magnetic Materials,2018:466.