醒脑开窍针刺法应用于脑梗死恢复期疗效观察
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摘要
目的:观察醒脑开窍针刺法治疗脑梗死(cerebral infarction,CI)恢复期的临床疗效。方法:选取2016年6月至2018年10月在本院就诊的脑梗死恢复期患者109例,按照随机数字表法分为对照组54例和试验组55例。对照组给予神经内科常规治疗,试验组在对照组治疗的基础上给予醒脑开窍针刺法。两组均连续治疗1个月。比较两组患者治疗前后神经功能缺损程度分级[采用美国国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)评定],双侧大脑中动脉(middle cerebral artery,MCA)、基底动脉(basilar artery,BA)的收缩期血流速度(velocity systolic,VS)及舒张期血流速度(velocity diastolic,VD)、血清C反应蛋白(c-reactive protein,CRP)及趋化因子Fractalkine(chemotactic factor,FKN)、日常生活能力(activities of daily living,ADL)。结果:与对照组比较,治疗后1个月试验组NIHSS评分明显降低(P <0. 05); MCA的VS值及BA、MCA的VD值明显升高(P <0. 05);血清CRP、FNK水平明显降低(P <0. 05),ADL评分明显升高(P <0. 05)。结论:醒脑开窍针刺法可改善脑梗死恢复期患者脑血流动力学参数,降低血清CRP、FNK水平,恢复神经功能,提高日常生活能力。
Objective: To observe the clinical curative effect of acupuncture for activating brain for resuscitation on cerebral infarction at stage of recovery time. Methods: A total of 109 patients with cerebral infarction at stage of recovery time treated in our hospital from June 2016 to October 2018 were selected and divided into the control group and the experiment group,with 53 and55 cases in each group respectively according to the random number table method. The control group was given routine treatment of neurology,while the experimental group was given acupuncture for activating brain for resuscitation on the basis of the treatment of the control group. Both groups were treated continuously for one month. The degrees of neurological impairment assessed by the National Institute of Health stroke scale(NIHSS),bilateral middle cerebral artery(MCA),basilar artery(BA) systolic blood flow velocity(VS) and diastolic blood flow velocity(VD),serum C-reactive protein(CRP),chemotactic factor(FKN),daily activities of living(ADL) before and after the treatment were compared between the two groups. Results: Compared with the control group,the NIHSS score of the experimental group decreased significantly(P < 0. 05),the VS value of MCA and the VD value of BA and MCA increased significantly(P < 0. 05),the serum CRP and FNK levels decreased significantly(P < 0. 05),and the ADL score increased significantly(P < 0. 05). Conclusion: Acupuncture for activating brain for resuscitation has a remarkable efficacy on cerebral infarction at stage of recovery time,can improve cerebral hemodynamic parameters,reduce serum CRP and FNK levels,restore nerve function and improve daily living ability.
Objective: To observe the clinical curative effect of acupuncture for activating brain for resuscitation on cerebral infarction at stage of recovery time. Methods: A total of 109 patients with cerebral infarction at stage of recovery time treated in our hospital from June 2016 to October 2018 were selected and divided into the control group and the experiment group,with 53 and55 cases in each group respectively according to the random number table method. The control group was given routine treatment of neurology,while the experimental group was given acupuncture for activating brain for resuscitation on the basis of the treatment of the control group. Both groups were treated continuously for one month. The degrees of neurological impairment assessed by the National Institute of Health stroke scale(NIHSS),bilateral middle cerebral artery(MCA),basilar artery(BA) systolic blood flow velocity(VS) and diastolic blood flow velocity(VD),serum C-reactive protein(CRP),chemotactic factor(FKN),daily activities of living(ADL) before and after the treatment were compared between the two groups. Results: Compared with the control group,the NIHSS score of the experimental group decreased significantly(P < 0. 05),the VS value of MCA and the VD value of BA and MCA increased significantly(P < 0. 05),the serum CRP and FNK levels decreased significantly(P < 0. 05),and the ADL score increased significantly(P < 0. 05). Conclusion: Acupuncture for activating brain for resuscitation has a remarkable efficacy on cerebral infarction at stage of recovery time,can improve cerebral hemodynamic parameters,reduce serum CRP and FNK levels,restore nerve function and improve daily living ability.
引文
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[5]方素娟,曾素冰,黄祥凌,等.中医情志干预对老年腹部手术患者术后认知功能的影响[J].广州中医药大学学报,2016,33(1):5-8.
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[7]张素勤,邱晓岚,魏玮,等.醒脑开窍针刺法结合头针疗法治疗老年脑梗死的临床疗效分析[J].实用老年医学,2017,31(7):23-25.
[8]陈勇军,张平,罗焱,等.脑心通胶囊对脑梗死患者颈动脉粥样硬化斑块和CRP及Hcy的影响[J].辽宁中医杂志,2017,44(9):134-135.
[9]文奎,朱和材,袁浩,等.醒脑开窍针法不同应用时机对急性脑梗死患者认知功能障碍的影响[J].现代中西医结合杂志,2016,25(26):2875-2878.
[10]陈思,陆斌,尹文伟,等.参芪扶正注射液联合尼莫地平对脑梗死患者血液指标的影响[J].中国药房,2016,27(5):683-685.
[2]贾建平,陈生弟.神经病学[M].7版.北京:人民卫生出版社,2013:175-186.
[3]国家中医药管理局.中医病证诊断疗效标准[S].北京:中国医药科技出版社,2012:39.
[4]武海霞.中医情志护理联合护理干预模式对脑梗死患者神经功能及心理状态的影响[J].现代诊断与治疗,2017,28(16):199-201.
[5]方素娟,曾素冰,黄祥凌,等.中医情志干预对老年腹部手术患者术后认知功能的影响[J].广州中医药大学学报,2016,33(1):5-8.
[6]李新颖.早期情志护理对老年脑梗死病人的临床辅助疗效及对负性情绪与依从性的影响[J].蚌埠医学院学报,2018,43(3):126-129.
[7]张素勤,邱晓岚,魏玮,等.醒脑开窍针刺法结合头针疗法治疗老年脑梗死的临床疗效分析[J].实用老年医学,2017,31(7):23-25.
[8]陈勇军,张平,罗焱,等.脑心通胶囊对脑梗死患者颈动脉粥样硬化斑块和CRP及Hcy的影响[J].辽宁中医杂志,2017,44(9):134-135.
[9]文奎,朱和材,袁浩,等.醒脑开窍针法不同应用时机对急性脑梗死患者认知功能障碍的影响[J].现代中西医结合杂志,2016,25(26):2875-2878.
[10]陈思,陆斌,尹文伟,等.参芪扶正注射液联合尼莫地平对脑梗死患者血液指标的影响[J].中国药房,2016,27(5):683-685.