李斌凉血潜阳法治疗寻常型银屑病组方规律分析
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摘要
目的:基于中医传承辅助平台系统(V2.5)软件分析李斌教授采用凉血潜阳法治疗寻常型银屑病的组方用药规律。方法:收集2016年2月9日至2017年2月9日李斌教授治疗寻常型银屑病初诊医案100例,运用"中医传承辅助平台(V2.5)"分析药物使用频次、关联规则和提取核心药物组合等。结果:常见的相关临床症状为少汗、冬重夏轻、舌质红等。100份处方中涉及91味中药,以外科六号方(由珍珠母、生牡蛎、灵磁石等12味中药组成)、桂枝、生地黄、菝葜、茜草等,产生中药药对12组,新处方8张。结论:通过中医传承辅助平台在一定程度上揭示了其治疗寻常型银屑病的处方用药规律,有助于提高中医治疗寻常型银屑病的疗效,为总结名中医经验提供客观依据。
Objective: Based on the traditional Chinese Medicine Inheritance platform(V2.5) software, analyze the prescription of Professor LI Bin to treat psoriasis vulgaris with the method of cooling blood and activating Yang. Methods: Cases from February 9, 2016 February 9 th-2017 Professor LI Bin in treatment of psoriasis vulgaris in newly diagnosed 100 cases, the use of "TCM inheritance auxiliary system(V2.5) analysis of drug use frequency, association rules, extracting core drug combination etc. Results: The common clinical symptoms were low sweating, heavy in winter and mild in summer, and red tongue. 100 prescriptions involved in 91 kinds of Chinese herbal medicine, surgery No. six(composed of 12 herbs, mother of pearl oysters, Magnetitum etc.), Ramulus Cinnamomi, radix rehmanniae, Smilax, madder, produced in 12 groups of new Chinese medicine, 8 prescriptions. Conclusion: TCM inheritance auxiliary platform reveals the law of prescription drugs of Professor LI Bin in the treatment of psoriasis vulgaris in a certain extent, help to improve the efficacy of traditional Chinese medicine in the treatment of psoriasis vulgaris, and provide objective basis for summarizing the experience of traditional Chinese medicine.
Objective: Based on the traditional Chinese Medicine Inheritance platform(V2.5) software, analyze the prescription of Professor LI Bin to treat psoriasis vulgaris with the method of cooling blood and activating Yang. Methods: Cases from February 9, 2016 February 9 th-2017 Professor LI Bin in treatment of psoriasis vulgaris in newly diagnosed 100 cases, the use of "TCM inheritance auxiliary system(V2.5) analysis of drug use frequency, association rules, extracting core drug combination etc. Results: The common clinical symptoms were low sweating, heavy in winter and mild in summer, and red tongue. 100 prescriptions involved in 91 kinds of Chinese herbal medicine, surgery No. six(composed of 12 herbs, mother of pearl oysters, Magnetitum etc.), Ramulus Cinnamomi, radix rehmanniae, Smilax, madder, produced in 12 groups of new Chinese medicine, 8 prescriptions. Conclusion: TCM inheritance auxiliary platform reveals the law of prescription drugs of Professor LI Bin in the treatment of psoriasis vulgaris in a certain extent, help to improve the efficacy of traditional Chinese medicine in the treatment of psoriasis vulgaris, and provide objective basis for summarizing the experience of traditional Chinese medicine.
引文
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[6] 张承江. 医学数据仓库与数据挖掘[M].北京: 中国中医药出版社,2008:67-73.
[7] 丁一琦. 基于Apriori算法的数据挖掘技术研究[J]. 现代计算机,2012,4(24):20-22.
[8] 陈克龙,樊永平.数据挖掘中的分类算法及其在中医证候学中的应用[J]. 中华中医药杂志,2011,26(3):469-473.
[9] 朱国福. 中药学[M]. 北京:清华大学出版社,2012.
[10] 马天,李斌. 李斌教授运用四重汤治疗皮肤病经验举隅[J]. 云南中医学院学报,2016,39(6):80-83.
[11] 张锡纯.医学衷中参西录[M].太原:山西科学技术出版社,2009:239.
[12] 许源,宿树兰,王团结,等.桂枝的化学成分与药理活性研究进展[J].中药材,2013,36(4):674-678.
[13] 徐华影,金妍. 夏枯草抗肿瘤转移活性成分及其作用机制研究[J].中药新药与临床药理,2015,24(3):351-355.
[14] 张玉杰,李明春,张华,等. 半边莲药理作用及机制的研究进展[J]. 中国药师,2015,18(8):1376-1378.
[15] 石梦莹,卢小路,熊思会,等. 半枝莲抗肿瘤药理研究进展[J]. 世界中医药,2016,11(4):741-743.
[16] 蒯仂,吴人杰,许逊哲,等. 沈小珩辨治肿瘤方药思想[J]. 上海中医药杂志,2016(12):1-3.