优泌乐25联合阿卡波糖对老年2型糖尿病患者糖脂代谢及C肽水平的影响
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摘要
目的探讨优泌乐25联合阿卡波糖对老年2型糖尿病患者糖脂代谢及C肽水平的影响。方法选择2017年4月—2018年8月广州市花都区人民医院收治的100例老年2型糖尿病患者作为研究对象,随机分为对照组和观察组,每组各50例。观察组给予优泌乐25联合阿卡波糖治疗,对照组给予阿卡波糖治疗。比较两组患者糖脂代谢及C肽水平。结果观察组糖脂代谢水平均低于对照组,差异有统计学意义(P<0.05);观察组C肽水平均低于对照组,差异有统计学意义(P<0.05)。结论老年2型糖尿病患者采用优泌乐25联合阿卡波糖治疗,可改善患者脂代谢异常,降低C肽水平,促进患者转归。
Objective To investigate the effect of Lipro 25 combined with acarbose on glucose and lipid metabolism and C-peptide level in elderly patients with type 2 diabetes mellitus. Methods 100 elderly patients with type 2 diabetes mellitus admitted to the hospital from April,2017 to August,2018 were randomly divided into control group and observation group,with 50 cases in each group. The observation group were treated with Lipro 25 combined with acarbose,and the control group were treated with acarbose.Glucose and lipid metabolism,and C peptide levels were compared between the two groups. Results The levels of glucose and lipid metabolism in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05). Conclusion Lipro 25 combined with acarbose can improve the abnormal lipid metabolism,reduce the level of C peptide,and promote the prognosis of elderly patients with type 2 diabetes mellitus.
Objective To investigate the effect of Lipro 25 combined with acarbose on glucose and lipid metabolism and C-peptide level in elderly patients with type 2 diabetes mellitus. Methods 100 elderly patients with type 2 diabetes mellitus admitted to the hospital from April,2017 to August,2018 were randomly divided into control group and observation group,with 50 cases in each group. The observation group were treated with Lipro 25 combined with acarbose,and the control group were treated with acarbose.Glucose and lipid metabolism,and C peptide levels were compared between the two groups. Results The levels of glucose and lipid metabolism in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05). Conclusion Lipro 25 combined with acarbose can improve the abnormal lipid metabolism,reduce the level of C peptide,and promote the prognosis of elderly patients with type 2 diabetes mellitus.
引文
[1]张淑萍.强化生活方式干预联合优泌乐25、阿卡波糖治疗老年2型糖尿病的效果观察[J].贵州医药,2016,40(6):608-610.
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[4]袁扬,梁军,刘艳梅,等.米格列奈对比阿卡波糖治疗2型糖尿病有效性和安全性的多中心、开放、随机对照临床研究[J].中国糖尿病杂志,2018,26(3):221-226.
[5]殷丽丽,段利忠,刘航宇,等.阿卡波糖和瑞格列奈治疗2型糖尿病的药物经济学评价[J].山西医科大学学报,2018,49(2):152-156.
[6]何兰香,计莉强,郑坚,等.尼莫地平联合阿卡波糖治疗糖尿病周围神经病变的临床研究[J].中国临床药理学杂志,2018,34(6):622-625.
[7]吴让兵,王华,杜小梅,等.甘精胰岛素结合阿卡波糖治疗对老年糖尿病患者糖化血红蛋白和空腹C肽水平的影响[J].中国老年学杂志,2018,38(6):1281-1283.
[8]陈劲松,栾晓军,许雪娟,等.拜唐苹治疗优泌乐25中餐后血糖控制不佳患者的疗效研究[J].中国现代医学杂志,2017,27(14):107-109.
[2]马丽娜,毕会民,高凌.阿卡波糖调节2型糖尿病大鼠肠道SGLT1表达的影响[J].职业与健康,2018,34(6):753-756.
[3]中华医学会糖尿病学分会.中国2型糖尿病防治指南(2013年版)[J].中国医学前沿杂志(电子版),2015,7(3):26-29.
[4]袁扬,梁军,刘艳梅,等.米格列奈对比阿卡波糖治疗2型糖尿病有效性和安全性的多中心、开放、随机对照临床研究[J].中国糖尿病杂志,2018,26(3):221-226.
[5]殷丽丽,段利忠,刘航宇,等.阿卡波糖和瑞格列奈治疗2型糖尿病的药物经济学评价[J].山西医科大学学报,2018,49(2):152-156.
[6]何兰香,计莉强,郑坚,等.尼莫地平联合阿卡波糖治疗糖尿病周围神经病变的临床研究[J].中国临床药理学杂志,2018,34(6):622-625.
[7]吴让兵,王华,杜小梅,等.甘精胰岛素结合阿卡波糖治疗对老年糖尿病患者糖化血红蛋白和空腹C肽水平的影响[J].中国老年学杂志,2018,38(6):1281-1283.
[8]陈劲松,栾晓军,许雪娟,等.拜唐苹治疗优泌乐25中餐后血糖控制不佳患者的疗效研究[J].中国现代医学杂志,2017,27(14):107-109.