中医证候诊断量表研究技术和方法探索
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摘要
为研究与建立中医证候诊断量表,课题组依托973计划项目基金的资助,以冠心病痰瘀互结证诊断量表的可行性,初步证实:文献系统评价和临床调查是中医证候诊断量表本底资料的重要来源,德尔菲法是筛选中医证候诊断量表条目达成共识的有效方法,层次分析法定权重能实现中医证候量化诊断的目标,采用诊断性试验设计的敏感度、特异度和ROC曲线下的面积来评价中医证候诊断量表的效能,后续研究,证明了这些技术和方法是可行性的,供同行借鉴参考。
To study and establish traditional Chinese medicine(TCM) syndrome diagnosis scale, with the support of project fund of 973 project, the research of the syndrome diagnosis scale of phlegm and blood stasis of coronary heart disease was taken as a research object.It had been preliminary confirmed that,systematic literature evaluation and clinical investigation were important sources of the background information of TCM syndrome diagnosis scale. Delphi method was an effective method to select the items of TCM syndrome diagnosis scale. Hierarchical analysis of legal weight could achieve the objective of quantitative diagnosis of TCM syndromes. The sensitivity, specificity and the area under the ROC curve were used to evaluate the effectiveness of TCM syndrome diagnostic scale. It could be proved these techniques and methods were feasible, step by step, also it could be referenced by peers.
To study and establish traditional Chinese medicine(TCM) syndrome diagnosis scale, with the support of project fund of 973 project, the research of the syndrome diagnosis scale of phlegm and blood stasis of coronary heart disease was taken as a research object.It had been preliminary confirmed that,systematic literature evaluation and clinical investigation were important sources of the background information of TCM syndrome diagnosis scale. Delphi method was an effective method to select the items of TCM syndrome diagnosis scale. Hierarchical analysis of legal weight could achieve the objective of quantitative diagnosis of TCM syndromes. The sensitivity, specificity and the area under the ROC curve were used to evaluate the effectiveness of TCM syndrome diagnostic scale. It could be proved these techniques and methods were feasible, step by step, also it could be referenced by peers.
引文
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[14]李先涛,谢蓉,彭丹虹,等.冠心病(胸痹心痛)痰瘀互结证辨证方式研究[J].辽宁中医杂志,2016,43(10):2073-2076.
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[16]谢蓉,王燕萍,彭丹虹,刘晓琪,苏雪芬,李先涛.中医症状规范化研究[J].河南中医,2017,37(7):1144-1146.
[2]李先涛,于春泉,王泓午.中风病先兆证临床特征表现文献系统评价[J].天津中医药,2013,30(2):115-117.
[3]王阶,安宇,何庆勇,等.基于患者报告结局的气滞血瘀证评价量表研制[J].中国实验方剂学杂志,2018,24(15):21-28.
[4]甘慧娟,陈玉招,李灿东.基于德尔菲法的气虚证自评量表条目筛选[J].中华中医药杂志,2018,33(2):507-511.
[5]世界中医药学会联合会痰证学专业委员会(筹委会).中医痰证诊断标准[J].中国中西医结合杂志,2016,36(7):776-780.
[6]谢蓉,彭丹虹,王燕萍,等.基于德尔菲法探讨中医痰证辨证依据[J].辽宁中医杂志,2017,44(1):16-20.
[7]李红,程英武.德尔菲法在中医学中的应用研究[J].湖北中医杂志,2013,35(3):27-28.
[8]张颖,季聪华,李秋爽,等.中医临床实践指南制修订中德尔菲法的统计分析方法[J].中华中医药杂志,2018,33(1):249-251.
[9]王孝宁,何苗,何钦成.层次分析法判断矩阵的构成方法及比较[J].中国卫生统计,2002,19(2):111-113.
[10]谢蓉,连新福,彭丹虹,等.基于层次分析法对冠心病痰证辨证依据重要性评估探讨[J].时珍国医国药,2017,28(9):2301-2304.
[11]毕颖斐,毛静远.层次分析法与Delphi法相结合的中医临床研究方法初探[J].中国中西医结合杂志,2012,32(5):689-692.
[12]陈新林,胡月,莫传伟,等.诊断准确性研究报告指南——STARD2015简介[J].中国循证医学杂志,2016,16(10):1227-1230.
[13]李先涛,尹立群,于春泉,等.中风先兆证临床特征专家问卷调查结果分析[J].天津中医药,2014,31(12):715-718.
[14]李先涛,谢蓉,彭丹虹,等.冠心病(胸痹心痛)痰瘀互结证辨证方式研究[J].辽宁中医杂志,2016,43(10):2073-2076.
[15]王子涛,李倩,苏涛,等.中医辨证思维与证候标准的多样性探讨[J].实用医学杂志,2015,31(21):3469-3472.
[16]谢蓉,王燕萍,彭丹虹,刘晓琪,苏雪芬,李先涛.中医症状规范化研究[J].河南中医,2017,37(7):1144-1146.