红花活性成分的提取及其改善皮肤微循环的功效评价
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摘要
为探究红花及其与桃胶复合提取物对皮肤微循环的影响及化妆品原料应用前景。在提取了红花及其与桃胶复合物活性成分后,采用以激光多普勒检测技术为主,生物红外热成像等检测技术为辅的检测方法,对比受试者使用前后血流灌注量、红外温度、皮肤粗糙度、水分含量和水分散失量的数据变化,以及受试者皮肤状态变化情况。结果显示涂抹红花提取物及红花与桃胶的提取复合物7d后,受试者的皮肤血流灌注量、面部温度、皮肤水分含量、水分散失量和皮肤鳞屑指数均有提高;红花提取物降低了细胞脱落数量,而红花和桃胶的复合提取物使细胞脱落数量增加。表明红花含有能够改善并促进皮肤微循环的活性物质,与桃胶制成复合物之后具有促进皮肤微循环的功效,可用作化妆品添加剂。
In order to explore the effect of safflower and its compound extract with peach gum on skin microcirculation and the application prospect of cosmetics raw materials, after extracting the active components of safflower and its complex with peach gum, laser Doppler detection technique and biological infrared thermal imaging technique were adopted in order to compare the data changes of blood perfusion, infrared temperature, skin roughness, moisture content, transepidermal water loss and skin condition of the subjects before and after use. The results show that the amount of skin blood flow, facial temperature, skin moisture content, transepidermal water loss and skin scale index of the subjects are increased after 7 days with the application of safflower extract and the extract complex of safflower and peach gum. In addition, the extract of safflower decreases the amount of cell shedding, while the compound extract of safflower and peach gum increased the amount of cell shedding. It indicates that safflower contains an active substance capable of improving and promoting skin microcirculation, and has a function of promoting skin microcirculation after being compounded with peach gum, which can be used as a cosmetic additive.
In order to explore the effect of safflower and its compound extract with peach gum on skin microcirculation and the application prospect of cosmetics raw materials, after extracting the active components of safflower and its complex with peach gum, laser Doppler detection technique and biological infrared thermal imaging technique were adopted in order to compare the data changes of blood perfusion, infrared temperature, skin roughness, moisture content, transepidermal water loss and skin condition of the subjects before and after use. The results show that the amount of skin blood flow, facial temperature, skin moisture content, transepidermal water loss and skin scale index of the subjects are increased after 7 days with the application of safflower extract and the extract complex of safflower and peach gum. In addition, the extract of safflower decreases the amount of cell shedding, while the compound extract of safflower and peach gum increased the amount of cell shedding. It indicates that safflower contains an active substance capable of improving and promoting skin microcirculation, and has a function of promoting skin microcirculation after being compounded with peach gum, which can be used as a cosmetic additive.
引文
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[13]Li Quan,Wu Zhimin.Principle and application of cosmetics against aging[J].Chinese Beauty Medicine,26(11):135-138.
[2]Hu Xiaojia,Yin Sha,Yuan Tingting,et al.Advances in studies on chemical constituents and pharmacological activities of Carthamus tinctorius[J].Journal of Pharmaceutical Practice,31(3):161-168,197.
[3]Wang Ping,Tong Yingpeng,Tao Luxia,et al.Advances in studies on chemical constituents and pharmacological activities of Crocus sativus[J].Chinese Herbal Medicine,2014,45(20):3015-3028.
[4]Yi Wenshi.Advances in the bioactivity of flavonoids[J].Guangzhou Chemical,2012(2):47-50.
[5]Xu Yan,Zhu Shi,Qian Haifeng,et al.Study on extraction,separation and composition properties of peach gum polysaccharide[J].Food Industry Technology,2008(1):66-68,71.
[6]Jun M S,Ha Y M,Kim H S,et al.Anti-inflammatory action of methanol extract of Carthamus tinctorius involves in heme oxygenase-1 induction[J].Journal of Ethnopharmacology,2011,133(2):524-530.
[7]Feng Tao,Yan Tingting,Yan Guorong,et al.A preliminary study on free radical scavenging ability of safflower extract[J].Journal of Tianjin Agricultural College,2010(1):6-9.
[8]Sun Suxin.The microcirculation of skin blood was detected by dual wavelength Doppler system[J].Progress in Laser and Optoelectronics,1984(11):46.
[9]Yue Xuexue,Zhu Wenyuan.Measurement of skin microcirculation[J].Chinese Medical Beauty Journal,2006(6):380-381.
[10]Yue Xuexing,Zhu Wenyuan,Ma Huijun,et al.Effects of hesperidin,β-aescin and tanshinone on skin microcirculation of nail fold[J].Journal of Clinical Dermatology,2005(7):427-429.
[11]He Yifan.Establishment of skin science evaluation method[C]//Proceedings of the 11th Session of China Cosmetics Symposium.Beijing:China Association of Fragrance Flavour and Cosmetic Industries,2016:4.
[12]Liu Jiecun,Ma Xiushui,Ma Xie,et al.A review of the study of laser Doppler vibrometer[J].Laser Magazine,2014,35(12):1-5.
[13]Li Quan,Wu Zhimin.Principle and application of cosmetics against aging[J].Chinese Beauty Medicine,26(11):135-138.