天然C_(19)-二萜生物碱的研究进展及其核磁共振波谱特征
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摘要
C_(19)-二萜生物碱是二萜生物碱中数量最多的一类,主要分布于毛茛科的乌头属、翠雀属和飞燕草属植物中.C_(19)-二萜生物碱结构复杂、生理活性显著,一直吸引着科研工作者的广泛关注.本文主要对2010～2018年报道的天然来源C_(19)-二萜生物碱的研究进行总结,并归纳了C_(19)-二萜生物碱各子类型的核磁共振(NMR)结构特征和解析方式,以期为C_(19)-二萜生物碱的深入研究及开发提供参考依据.
Majority of diterpenoid alkaloids are C_(19)-diterpenoid alkaloids found in the plants from the genera Aconitum,Delphinium and Consolida(Ranunculaceae). C_(19)-diterpenoid alkaloids have attached lots of research interests due to their complex structures and remarkable pharmacological activities. This paper reviewed the structural features of natural C_(19)-diterpenoid alkaloids reported in literature from 2010 to 2018, focusing on the NMR spectral characteristics of different subtypes of C_(19)-diterpenoid alkaloids and how their structures could be elucidated from the NMR data. The work may provide a reference for the further research and development of C_(19)-diterpenoid alkaloids.
Majority of diterpenoid alkaloids are C_(19)-diterpenoid alkaloids found in the plants from the genera Aconitum,Delphinium and Consolida(Ranunculaceae). C_(19)-diterpenoid alkaloids have attached lots of research interests due to their complex structures and remarkable pharmacological activities. This paper reviewed the structural features of natural C_(19)-diterpenoid alkaloids reported in literature from 2010 to 2018, focusing on the NMR spectral characteristics of different subtypes of C_(19)-diterpenoid alkaloids and how their structures could be elucidated from the NMR data. The work may provide a reference for the further research and development of C_(19)-diterpenoid alkaloids.
引文
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