低温等离子射频消融术治疗早期声门型喉癌的疗效观察
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摘要
目的探讨低温等离子射频消融术治疗早期声门型喉癌的疗效。方法回顾性分析80例早期声门型喉癌患者的临床资料,其中37例接受低温等离子射频消融术治疗为C组,另43例接受传统喉切开治疗为T组。术后均获随访12~27个月,比较2组手术时间、疼痛VAS评分、术后并发症、黏膜恢复情况及术后复发率。结果 C组手术时间为(12.31±2.02)min、VAS评分为(2.22±0.44)分、黏膜恢复评分为(2.28±0.65)分、并发症发生率为2.7%,T组分别为(99.87±11.15)min、(3.97±0.53)分、(3.73±0.39)分、20.9%,2组差异均有统计学意义(P<0.05)。C组术后复发率为5.4%,T组为6.9%,2组术后复发率差异无统计学意义(P>0.05)。结论低温等离子射频消融术治疗早期声门型喉癌短期内安全有效。
Objective To investigate the effect of Coblation in the treatment of early glottic carcinoma. Methods The clinical data of 80 cases of early glottic carcinoma were retrospectivly analyzed,37 cases treated with Coblation as group C,and the other 43 cases treated with conventional incision of larynx as group T. All patients were followed up for 12 ~ 27 months,and the operation time,pain VAS score,postoperative complications,mucosal recovery and recurrence rate were compared between the 2 groups. Results The group C's operation time was( 12. 31 ± 2. 02) min,VAS score was( 2. 22 ± 0. 44),mucosal recovery score was( 2. 28 ± 0. 65) and postoperative complications was 2. 7%,and those of the group T were( 99. 87 ± 11. 15) min,( 3. 97 ±0. 53),( 3. 73 ± 0. 39),and 20. 9%,the 2 groups were statistically different( P < 0. 05). The group C 's recurrence rate was5. 4%,and that of the group T was 6. 9%,the 2 groups were not statistically different( P > 0. 05). Conclusion Coblation is effective and safe in the treatment of early glottic carcinoma.
Objective To investigate the effect of Coblation in the treatment of early glottic carcinoma. Methods The clinical data of 80 cases of early glottic carcinoma were retrospectivly analyzed,37 cases treated with Coblation as group C,and the other 43 cases treated with conventional incision of larynx as group T. All patients were followed up for 12 ~ 27 months,and the operation time,pain VAS score,postoperative complications,mucosal recovery and recurrence rate were compared between the 2 groups. Results The group C's operation time was( 12. 31 ± 2. 02) min,VAS score was( 2. 22 ± 0. 44),mucosal recovery score was( 2. 28 ± 0. 65) and postoperative complications was 2. 7%,and those of the group T were( 99. 87 ± 11. 15) min,( 3. 97 ±0. 53),( 3. 73 ± 0. 39),and 20. 9%,the 2 groups were statistically different( P < 0. 05). The group C 's recurrence rate was5. 4%,and that of the group T was 6. 9%,the 2 groups were not statistically different( P > 0. 05). Conclusion Coblation is effective and safe in the treatment of early glottic carcinoma.
引文
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[9]双羽,李超,黄永望,等.声门型喉癌低温等离子射频消融术治疗后局部复发与前联合受侵犯的关系[J].肿瘤防治研究,2015,42(10):1024-1026.
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[2]赵卫民,黄武,廖兰芳,等.显微喉镜下等离子射频手术治疗早期声门型喉癌33例临床分析[J].广西医科大学学报,2014,31(4):690-691.
[3]尹显祥,张珺,张园园.早期声门型喉癌治疗的预后分析[J].中国耳鼻咽喉头颈外科,2013,20(4):193-195.
[4]李言冰,蔡晓军,冯劼妮,等.早期声门型喉癌治疗进展[J].中国激光医学杂志,2013,22(5):289-293.
[5]张庆丰,刘得龙,宋伟,等.等离子射频消融术治疗早期声门型喉癌的疗效观察[J].临床耳鼻咽喉头颈外科杂志,2011,25(18):855-856.
[6]赵春红,李玉杰,于敏.对CO2激光与等离子射频消融术治疗早期声门型喉癌疗效比较[J].听力学及言语疾病杂志,2015,23(3):307-309.
[7]肖其珍.微创手术及传统手术治疗声门型早期喉癌及癌前病变的临床效果比较[J].医学综述,2015,21(11):2088-2090.
[8]双羽,李超,黄永望,等.低温等离子射频消融术与CO2激光治疗早期声门型喉癌疗效比较[J].听力学及言语疾病杂志,2015,23(4):372-376.
[9]双羽,李超,黄永望,等.声门型喉癌低温等离子射频消融术治疗后局部复发与前联合受侵犯的关系[J].肿瘤防治研究,2015,42(10):1024-1026.
[10]Cukurova I,Gümüsoy M,etinkaya EA,et al.A comparison of histopathological results of conventional surgery and transoral radiofrequency ablation in early stage laryngeal carcinoma[J].Kulak Burun Bogaz Ihtis Derg,2013,23(6):325-330.