杏鲍菇多糖对糖尿病小鼠的降血糖作用
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摘要
通过对正常小鼠和糖尿病小鼠灌喂杏鲍菇(Pleurotus eryngii)多糖溶液,研究了杏鲍菇多糖的降血糖作用。结果表明,当浓度在200 mg·kg~(-1)以上时,杏鲍菇多糖能够显著降低糖尿病小鼠的血糖含量,抑制体重下降,缓解多饮、多食、多尿等糖尿病症状,具有作为良好的糖尿病治疗药物开发潜力。
The reduction effect of Pleurotus eryngii polysaccharides on blood glucose was analyzed in normal mice and diabetic mice. The results showed that when the the mass fraction was above 200 mg·kg~(-1), the P. eryngii polysaccharides could significantly reduce the glucose content and the weight loss of diabetic mice, and relieve the exceeded drinking, eating and urinary diabetic symptoms. It has the potential to be used as a good drug for the treatment of diabetes drug.
The reduction effect of Pleurotus eryngii polysaccharides on blood glucose was analyzed in normal mice and diabetic mice. The results showed that when the the mass fraction was above 200 mg·kg~(-1), the P. eryngii polysaccharides could significantly reduce the glucose content and the weight loss of diabetic mice, and relieve the exceeded drinking, eating and urinary diabetic symptoms. It has the potential to be used as a good drug for the treatment of diabetes drug.
引文
[1]王海洋,李红月,徐多多.杏鲍菇多糖的研究进展[J].安徽农业科学,2015,43(9):14-15,18.
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[7]Liu Y,Chen Z,Liang Y.Extraction and anti-diabetic activity on alloxan-induced diabetic mice of polysaccharides from huidouba[J].Chemical Research in Chinese Universities,2009,25(5):681-685.
[8]吴家睿.2型糖尿病发生发展的分子机制研究[J].生命科学,2006,18(5):411-413.
[9]林素丽,朱科学,宋丹,等.黑灵芝多糖对Ⅱ型糖尿病大鼠肝脏氧化应激损伤的保护作用[J].食品科学,2013,34(21):302-305.
[10]亢建国,龚云.运动结合灵芝多糖对糖尿病大鼠血脂的影响[J].辽宁体育科技,2013,35(6):29-31.
[11]何兴帅,欧阳玉倩,冯翠萍,等.巴氏蘑菇多糖对糖尿病小鼠糖代谢调节机制[J].中国食用菌,2017,36(2):33-37.
[2]姚秋萍,杨琼,卫亚丽,等.杏鲍菇多糖研究进展[J].食品工业科技,2017,38(21):347-351.
[3]刘海英,范刘士博.杏鲍菇多糖对S180荷瘤小鼠的保护作用[J].食品科学,2015,36(3):198-201.
[4]李鹏飞,李志鹏,于婷,等.杏鲍菇多糖抗疲劳作用的研究[J].延边大学学报:自然科学版,2014,40(2):177-181.
[5]郑素玲,郭立英,范永山.杏鲍菇多糖对老龄小鼠抗疲劳能力的影响[J].食品科学,2010,31(7):269-271.
[6]张俊会,王谦.杏鲍菇多糖的抗氧化活性研究[J].中国食用菌,2003,22(2):38-39.
[7]Liu Y,Chen Z,Liang Y.Extraction and anti-diabetic activity on alloxan-induced diabetic mice of polysaccharides from huidouba[J].Chemical Research in Chinese Universities,2009,25(5):681-685.
[8]吴家睿.2型糖尿病发生发展的分子机制研究[J].生命科学,2006,18(5):411-413.
[9]林素丽,朱科学,宋丹,等.黑灵芝多糖对Ⅱ型糖尿病大鼠肝脏氧化应激损伤的保护作用[J].食品科学,2013,34(21):302-305.
[10]亢建国,龚云.运动结合灵芝多糖对糖尿病大鼠血脂的影响[J].辽宁体育科技,2013,35(6):29-31.
[11]何兴帅,欧阳玉倩,冯翠萍,等.巴氏蘑菇多糖对糖尿病小鼠糖代谢调节机制[J].中国食用菌,2017,36(2):33-37.