心力衰竭彩色多普勒超声心动图与B型脑钠肽及心功能分级的相关性
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摘要
目的探讨心力衰竭彩色多普勒超声心动图指标与B型脑钠肽(BNP)及心功能分级的相关性。方法选择2015年2月至2017年12月本院收治的心力衰竭患者80例,按不同疾病类型将其分为观察组(40例,急性心力衰竭)与对照组(40例,慢性心力衰竭)。比较两组患者的BNP水平及NYHA心功能分级,并分析急性或慢性心力衰竭患者LVEF与BNP水平及NYHA心功能分级的相关性。结果观察组患者的LVEF、E及A均显著低于对照组,血清BNP水平及NYHA心功能分级显著高于对照组(P<0.05)。心力衰竭患者LVEF与BNP水平、NYHA心功能分级均呈负相关(P<0.05)。结论 LVEF降低者出现心力衰竭的几率显著增加,尤其应对于急性起病者引起重视并及时干预,以改善患者预后。
Objective To investigate the correlation between color Doppler echocardiography and B-type natriuretic peptide(BNP) and cardiac function classification in patients with heart failure. Methods From February 2015 to December 2017, 80 patients with heart failure admitted to our hospital were selected. Patients were divided into observation group(40 cases, acute heart failure) and control group(40 cases, chronic heart failure) according to the different disease types. The levels of BNP and NYHA cardiac function classification were compared between the two groups, and the correlation between LVEF and levels of BNP and NYHA cardiac function classification in patients with acute or chronic heart failure was analyzed. Results The LVEF, E and A in the observation group were significantly lower than those in the control group, the level of serum BNP and the NYHA cardiac function grade were significantly higher than those in the control group(P<0.05).The level of LVEF was negatively correlated with the level of BNP and NYHA cardiac function classification in patients with heart failure(P <0.05). Conclusion The risk of heart failure increased significantly in patients with lower LVEF,especially in patients with acute onset, and timely intervention should be taken to improve the prognosis of patients.
Objective To investigate the correlation between color Doppler echocardiography and B-type natriuretic peptide(BNP) and cardiac function classification in patients with heart failure. Methods From February 2015 to December 2017, 80 patients with heart failure admitted to our hospital were selected. Patients were divided into observation group(40 cases, acute heart failure) and control group(40 cases, chronic heart failure) according to the different disease types. The levels of BNP and NYHA cardiac function classification were compared between the two groups, and the correlation between LVEF and levels of BNP and NYHA cardiac function classification in patients with acute or chronic heart failure was analyzed. Results The LVEF, E and A in the observation group were significantly lower than those in the control group, the level of serum BNP and the NYHA cardiac function grade were significantly higher than those in the control group(P<0.05).The level of LVEF was negatively correlated with the level of BNP and NYHA cardiac function classification in patients with heart failure(P <0.05). Conclusion The risk of heart failure increased significantly in patients with lower LVEF,especially in patients with acute onset, and timely intervention should be taken to improve the prognosis of patients.
引文
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[5]金鑫,郭炳彦,李拥军.分泌型卷曲相关蛋白5和N末端B型利钠肽原与慢性心力衰竭的相关性研究[J].河北医科大学学报,2017,38(12):1365-1368,1372.
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[2]郭慧佳,张建义,胡亚军,等.高敏肌钙蛋白T与慢性心力衰竭的相关性及对急性心肌梗死的鉴别意义[J].中国全科医学,2014,17(8):871-874.
[3]杨涛,何建国.左心疾病相关性肺动脉高压预后的研究进展[J].中国循环杂志,2013,28(3):237-239.
[4]张颖,韩素霞,赵栋,等.慢性心力衰竭患者伴肺部感染与免疫功能的相关性分析[J].中华医院感染学杂志,2016,26(14):3167-3169.
[5]金鑫,郭炳彦,李拥军.分泌型卷曲相关蛋白5和N末端B型利钠肽原与慢性心力衰竭的相关性研究[J].河北医科大学学报,2017,38(12):1365-1368,1372.
[6]童春玲,陈富梅,钱留军.冠心病心力衰竭患者血尿酸、脑钠肽、高敏C反应蛋白与左室射血分数的相关性分析[J].中医临床研究,2016,8(34):133-135.
[7]黄影兰,陈文智,幸日坤,等.B型钠尿肽在心力衰竭诊治中的应用研究[J].中国医学创新,2015,12(15):41-44.