半夏泻心汤用于胃病患者治疗中的临床效果分析
|
摘要
目的:探析半夏泻心汤用于胃病患者治疗中的临床效果。方法:随机抽取我院收治的胃病患者60例为对象进行研究,采用双盲随机法将60例患者随机分为观察组和对照组,每组患者各30例。对照组采取常规西药治疗,即口服雷贝拉唑钠肠溶胶囊+硫酸阿托品片+复方氢氧化铝片等,而在此基础上观察组采用半夏泻心汤治疗,组方包括甘草、川莲、红枣、党参、黄芩、干姜、半夏等,随症加减。观察比较两组治疗前后临床症状(胃脘痛、胀满、嗳气、纳差等)积分、肠胃功能相关生化指标(血清生长抑素、胃动素、胃泌素等)水平等变化、临床效果以及不良反应情况。结果:两组治疗前胃脘痛、胀满、嗳气、纳差等症状积分对比差异无统计学意义(P> 0.05);而治疗后观察组胃脘痛、胀满、嗳气、纳差等症状积分较对照组显著较低,P <0.05,差异具有统计学意义。两组治疗前血清生长抑素、胃动素、胃泌素等对比,P> 0.05,差异无统计学意义;而治疗后观察组血清生长抑素较对照组显著较低,而胃动素、胃泌素等水平较对照组显著较高,且组间对比差异具有统计学意义(P <0.05)。观察组显效21例、有效7例、无效2例,而对照组显效16例、有效6例、无效8例,观察组总有效率为93.33%(28/30)与对照组73.33%(22/30)相比明显较高,P <0.05,差异具有统计学意义。观察组出现头晕2例、恶心1例、呕吐1例,对照组出现头晕3例、恶心3例、呕吐2例,观察组不良反应率13.33%(4/30)与对照组26.67%(8/30)相比明显较低,P <0.05,差异具有统计学意义。结论:在常规西药的基础上联合半夏泻心汤治疗胃病患者的临床效果非常显著,既能显著改善各种临床症状,且还能促进其病情康复,减少各种不良反应,因此值得应用推广。
Objective: To observe clinical effects of the Banxia Xiexin decoction(半夏泻心汤) on gastropathy. Methods: 60 patients with gastropathy were randomly divided into the observation group and the control group, 30 cases in each. The control group was treated with routine western medicine, such as rebelazole sodium enteric capsule, atropine sulfate tablets and compound aluminum hydroxide tablets, and the observation group was treated with the Banxia Xiexin decoction more. After treatment, the symptom integral and serum somatostatin in the observation group were lower than those in the control group(P<0.05). The levels of motilin and gastrin in the observation group were higher than those in the control group(P<0.05). The total efficiency rate was 93.33% in the observation group,higher than 73.33% in the control group(P<0.05). The adverse effects rate was 13.33% in the observation group, lower than 26.67% in the control group(P<0.05). Conclusion: The routine western medicine plus the Banxia Xiexin decoction is effective, safe and worthy of promotion.
Objective: To observe clinical effects of the Banxia Xiexin decoction(半夏泻心汤) on gastropathy. Methods: 60 patients with gastropathy were randomly divided into the observation group and the control group, 30 cases in each. The control group was treated with routine western medicine, such as rebelazole sodium enteric capsule, atropine sulfate tablets and compound aluminum hydroxide tablets, and the observation group was treated with the Banxia Xiexin decoction more. After treatment, the symptom integral and serum somatostatin in the observation group were lower than those in the control group(P<0.05). The levels of motilin and gastrin in the observation group were higher than those in the control group(P<0.05). The total efficiency rate was 93.33% in the observation group,higher than 73.33% in the control group(P<0.05). The adverse effects rate was 13.33% in the observation group, lower than 26.67% in the control group(P<0.05). Conclusion: The routine western medicine plus the Banxia Xiexin decoction is effective, safe and worthy of promotion.
引文
[1]崔喜英.半夏泻心汤治疗慢性胃病的临床观察[J].光明中医,2017,32(23):3418-3420.
[2]范鲁华,查红群,胡春霞.半夏泻心汤治疗胃病的效果分析[J].当代医学,2017,23(01):29-30.
[3]郑仁省.半夏泻心汤治疗胃病188例[J].西部中医药,2016,29(02):103-104.
[4]丁宪春,夏秋敏,王淑敏.半夏泻心汤治疗寒热错杂型胃病的辨证分析[J].中国中医基础医学杂志,2015,21(05):598-599.
[5]朱丽丽,赵晓峰,郭海,等.半夏泻心汤治疗胃病的临床疗效[J].实用医学杂志,2015,31(09):1546-1547.
[6]孙艳.半夏泻心汤治疗胃病临床价值研究[J].亚太传统医药,2014,10(18):107-108.
[7]王志.探讨半夏泻心汤治疗慢性胃病的临床疗效[J].中国农村卫生,2018(05):66-67.
[8]朴成日.半夏泻心汤在急诊胃病中的应用心得[J/CD].中西医结合心血管病电子杂志,2016,4(21):117-118.
[9]李元平.半夏泻心汤加味治疗胃病[J].亚太传统医药,2015,11(04):123-124.
[10]吴琼,周宁,李琦.中医药治疗幽门螺杆菌相关性胃病研究进展[J].中华中医药杂志,2012,27(01):152-155.
[11]江建勋.半夏泻心汤治疗幽门螺杆菌相关性胃炎40例疗效研究[J].中医临床研究,2015,7(22):96-98.
[12]闫平.半夏泻心汤加味治疗慢性胃病临床疗效观察[J].中医临床研究,2012,4(03):110,112.
[2]范鲁华,查红群,胡春霞.半夏泻心汤治疗胃病的效果分析[J].当代医学,2017,23(01):29-30.
[3]郑仁省.半夏泻心汤治疗胃病188例[J].西部中医药,2016,29(02):103-104.
[4]丁宪春,夏秋敏,王淑敏.半夏泻心汤治疗寒热错杂型胃病的辨证分析[J].中国中医基础医学杂志,2015,21(05):598-599.
[5]朱丽丽,赵晓峰,郭海,等.半夏泻心汤治疗胃病的临床疗效[J].实用医学杂志,2015,31(09):1546-1547.
[6]孙艳.半夏泻心汤治疗胃病临床价值研究[J].亚太传统医药,2014,10(18):107-108.
[7]王志.探讨半夏泻心汤治疗慢性胃病的临床疗效[J].中国农村卫生,2018(05):66-67.
[8]朴成日.半夏泻心汤在急诊胃病中的应用心得[J/CD].中西医结合心血管病电子杂志,2016,4(21):117-118.
[9]李元平.半夏泻心汤加味治疗胃病[J].亚太传统医药,2015,11(04):123-124.
[10]吴琼,周宁,李琦.中医药治疗幽门螺杆菌相关性胃病研究进展[J].中华中医药杂志,2012,27(01):152-155.
[11]江建勋.半夏泻心汤治疗幽门螺杆菌相关性胃炎40例疗效研究[J].中医临床研究,2015,7(22):96-98.
[12]闫平.半夏泻心汤加味治疗慢性胃病临床疗效观察[J].中医临床研究,2012,4(03):110,112.