流动注射化学发光法在线监测饮用水中赭曲霉毒素A突发污染
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摘要
基于赭曲霉毒素A对鲁米诺—高碘酸钠—吐温20发光体系的抑制作用,建立了快速在线监测赭曲霉毒素A的新方法。经响应面优化试验条件后,该方法的线性范围为0.006～1.000μg/mL;检出限为1.74×10~(-3)μg/mL(S/N=3);加标回收率为80.6%～92.4%。对浓度0.02μg/mL赭曲霉毒素A平行测定11次,相对标准偏差(RSD)为1.68%。该方法快捷简便,可用于饮用水中赭曲霉毒素A突发污染的快速在线检测和预警。
Based on quenching effect of ochratoxin A on chemiluminescence(CL)reaction of luminol-NaIO_4 system catalyzing by Tween 20,a novel flow-injection chemiluminescence method was developed for the rapid on-line determination of possible sudden pollution of ochratoxin A in drinking water.Under the optimum conditions of response surface experiment,the linear range for ochratoxin A was 0.006～1.000μg/mL with a detection limit of 1.74×10~(-3)μg/mL and recovery of 80.6%～92.4%.The relative standard deviation(RSD)was 1.68% by analyzing samples containing 0.02μg/mL ochratoxin A(n=11).This method was founs convenient to operate,and couls be applied to the rapid emergency warning and real-time monitoring of ochratoxin A in drinking water.
Based on quenching effect of ochratoxin A on chemiluminescence(CL)reaction of luminol-NaIO_4 system catalyzing by Tween 20,a novel flow-injection chemiluminescence method was developed for the rapid on-line determination of possible sudden pollution of ochratoxin A in drinking water.Under the optimum conditions of response surface experiment,the linear range for ochratoxin A was 0.006～1.000μg/mL with a detection limit of 1.74×10~(-3)μg/mL and recovery of 80.6%～92.4%.The relative standard deviation(RSD)was 1.68% by analyzing samples containing 0.02μg/mL ochratoxin A(n=11).This method was founs convenient to operate,and couls be applied to the rapid emergency warning and real-time monitoring of ochratoxin A in drinking water.
引文
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[24]LI Yin-huan,PENG Wen-chang,YOU Xiao-ying.Determination of dopamine by exploiting the catalytic effect of hemoglobin-stabilized gold nanoclusters on the luminolNaIO4chemiluminescence system[J].Microchimica Acta,2017,184(9):3 539-3 545.
[25]TIMOFEEVA I I,VAKH C S,BULATOV A V,et al.Flow analysis with chemiluminescence detection:recent advances and applications[J].Talanta,2018,179:246-270.
[26]杨盼盼,唐书泽,吴事正,等.流动注射化学发光法在线检测饮用水中脱氧雪腐镰刀菌烯醇[J].食品与机械,2018,34(5):70-76.
[27]MUKERJEE P,MYSELS K J.Critical micelle concentrations of aqueous surfactant systems[J].Journal of Colloid&Interface Science,1971,38(3):671-672.
[28]LI Shi-feng,LI Xiang-zi,XU Jing,et al.Flow-injection chemiluminescence determination of polyphenols using luminolNaIO4-gold nanoparticles system[J].Talanta,2008,75(1):32-37.
[29]SHI Ming,HUANG Yong,ZHAO Jing-jin,et al.Quantification of glutathione in single cells from rat liver by microchip electrophoresis with chemiluminescence detection[J].Talanta,2018,179:466-471.
[2]HARTMANN J,VAN Der Aa M,WUIJTS S,et al.Risk governance of potential emerging risks to drinking water quality:analysing current practices[J].Environmental Science&Policy,2018,84:97-104.
[3]LI Zi-jian,JENNINGS A.Global variations in pesticide regulations and health risk assessment of maximum concentration levels in drinking water[J].Journal of Environmental Management,2018,212:384-394.
[4]张旭辉,唐书泽,邓小玲,等.流动注射化学发光法在线检测饮用水中的3-硝基丙酸[J].食品与机械,2016,32(11):45-49.
[5]RAMESH C,JAYAGOUDAR S.A review of ochratoxin contamination effects and its control[J].International Journal of Agricultural Technology,2017,13(4):457-468.
[6]AFSHAR P,SHOKRZADEH M,KALHORI S,et al.Occurrence of ochratoxin A and aflatoxin M1in human breast milk in Sari,Iran[J].Food Control,2013,31(2):525-529.
[7]HEUSSNER A H,BINGLE L E H.Comparative ochratoxin toxicity:a review of the available data[J].Toxins,2015,7(10):4 253-4 282.
[8]丁平,侯亚莉,王永红,等.赭曲霉毒素A的危害与防治[J].中国饲料,2010(17):33-36.
[9]CABALLERO-CASERO N,GARCIA-FONSECA S,RUB-IO S.Restricted access supramolecular solvents for the simultaneous extraction and cleanup of ochratoxin A in spices subjected to EU regulation[J].Food Control,2018,88:33-39.
[10]CAMPONE L,PICCINELLI A L,CELANO R,et al.Rapid and automated on-line solid phase extraction HPLC-MS/MS with peak focusing for the determination of ochratoxin A in wine samples[J].Food Chemistry,2018,244:128-135.
[11]KARCZMARCZYK A,HAUPT K,FELLER K H.Development of a QCM-D biosensor for ochratoxin A detection in red wine[J].Talanta,2017,166:193-197.
[12]叶云锋,李研东,吴雨洋,等.化学发光免疫分析方法检测粮食谷物中赭曲霉毒素A残留[J].食品安全质量检测学报,2017,8(7):2 787-2 791.
[13]吕蕾,赵阳阳,刘仁杰,等.基于纳米金与适配体的赭曲霉毒素A检测方法研究[J].食品与机械,2017,33(7):56-60.
[14]李素,肖义陂,武乐,等.金标记羟胺放大化学发光检测赭曲霉毒素A[J].分析测试学报,2018,37(1):57-61.
[15]KHATAEE A,HASANZADEH A,LOTFI R,et al.Enhanced chemiluminescence of carminic acid-permanganate by CdS quantum dots and its application for sensitive quenchometric flow injection assays of cloxacillin[J].Talanta,2016,152:171-178.
[16]VAKH C,EVDOKIMOVA E,POCHIVALOV A,et al.Anovel flow injection chemiluminescence method for automated and miniaturized determination of phenols in smoked food samples[J].Food Chemistry,2017,237:929-935.
[17]IRANIFAM M,FATHINIA M,SADEGHI R T,et al.Anovel selenium nanoparticles-enhanced chemiluminescence system for determination of dinitrobutylphenol[J].Talanta,2013,107(2):263-269.
[18]IRANIFAM M.Analytical applications of chemiluminescence methods for cancer detection and therapy[J].Trends in Analytical Chemistry,2014,59:156-183.
[19]吴事正,张旭辉,杨盼盼,等.流动注射化学发光法对饮用水中黄绿青霉素的在线检测[J].食品科学,2017(24):259-265.
[20]马强,朱定波,杨杏芳,等.鲁米诺-铁氰化钾流动注射化学发光体系测定饮用水中棒曲霉素[J].食品工业科技,2013,34(15):306-308.
[21]吕小虎,陆明刚.过氧化氢-次氯酸钠氧化鲁米诺发光的研究[J].光谱学与光谱分析,1994(1):123-127.
[22]MEHER A K,LABHSETWAR N,BANSIWAL A.An improved method for direct estimation of free cyanide in drinking water by ion chromatography-pulsed amperometry detection(IC-PAD)on gold working electrode[J].Food Chemistry,2018,240:131-138.
[23]LI Qian-qian,ZHANG Li-juan,LI Jin-ge,et al.Nanomaterial-amplified chemiluminescence systems and their applications in bioassays[J].Trends in Analytical Chemistry,2011,30(2):401-413.
[24]LI Yin-huan,PENG Wen-chang,YOU Xiao-ying.Determination of dopamine by exploiting the catalytic effect of hemoglobin-stabilized gold nanoclusters on the luminolNaIO4chemiluminescence system[J].Microchimica Acta,2017,184(9):3 539-3 545.
[25]TIMOFEEVA I I,VAKH C S,BULATOV A V,et al.Flow analysis with chemiluminescence detection:recent advances and applications[J].Talanta,2018,179:246-270.
[26]杨盼盼,唐书泽,吴事正,等.流动注射化学发光法在线检测饮用水中脱氧雪腐镰刀菌烯醇[J].食品与机械,2018,34(5):70-76.
[27]MUKERJEE P,MYSELS K J.Critical micelle concentrations of aqueous surfactant systems[J].Journal of Colloid&Interface Science,1971,38(3):671-672.
[28]LI Shi-feng,LI Xiang-zi,XU Jing,et al.Flow-injection chemiluminescence determination of polyphenols using luminolNaIO4-gold nanoparticles system[J].Talanta,2008,75(1):32-37.
[29]SHI Ming,HUANG Yong,ZHAO Jing-jin,et al.Quantification of glutathione in single cells from rat liver by microchip electrophoresis with chemiluminescence detection[J].Talanta,2018,179:466-471.