冠心病诊断中应用脂蛋白(a)和胆红素联合检验的意义探析
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摘要
目的探析联合检验脂蛋白(a)和胆红素诊断冠心病的临床意义。方法 2016年1月—2017年8月,选取我院150例冠心病患者为观察组、150例健康体检者为对照组,使用全自动生化分析仪进行检测,钒酸氧化法检测胆红素,免疫比浊法检测脂蛋白(a),对比两组脂蛋白(a)和胆红素水平。结果观察组脂蛋白(a)水平高于对照组,总胆红素、直接胆红素、间接胆红素水平低于对照组,对比差异有统计学意义(P<0.05)。结论冠心病患者的胆红素和脂蛋白(a)水平与健康人群相比差异有统计学意义,联合检验用于冠心病的诊断具有一定的临床意义。
Objective To explore the clinical significance of combined detection of lipoprotein(a) and bilirubin in the diagnosis of coronary heart disease. Methods From January 2016 to August 2017, 150 patients with coronary heart disease were selected as observation group and 150 healthy persons as control group in our hospital. The automatic biochemical analyzer was used for detection. Vanadate oxidation method was used to detect bilirubin. The lipoprotein(a) was detected by immunoturbidimetry and the levels of lipoprotein(a) and bilirubin were compared between the two groups. Results The level of lipoprotein(a) in the observation group was higher than that in the control group. The levels of total bilirubin, direct bilirubin, and indirect bilirubin were lower than those in the control group. There was a significant difference between the two groups(P < 0.05). Conclusion The levels of bilirubin and lipoprotein(a) in patients with coronary heart disease are significantly different from those in healthy people. The combined test has a certain clinical significance in the diagnosis of coronary heart disease.
Objective To explore the clinical significance of combined detection of lipoprotein(a) and bilirubin in the diagnosis of coronary heart disease. Methods From January 2016 to August 2017, 150 patients with coronary heart disease were selected as observation group and 150 healthy persons as control group in our hospital. The automatic biochemical analyzer was used for detection. Vanadate oxidation method was used to detect bilirubin. The lipoprotein(a) was detected by immunoturbidimetry and the levels of lipoprotein(a) and bilirubin were compared between the two groups. Results The level of lipoprotein(a) in the observation group was higher than that in the control group. The levels of total bilirubin, direct bilirubin, and indirect bilirubin were lower than those in the control group. There was a significant difference between the two groups(P < 0.05). Conclusion The levels of bilirubin and lipoprotein(a) in patients with coronary heart disease are significantly different from those in healthy people. The combined test has a certain clinical significance in the diagnosis of coronary heart disease.
引文
[1]阮云军,宋仕聪.胸痛疑诊冠心病患者的诊断评估思路进展[J].中国实验诊断学,2018,22(1):154-156.
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[8]徐贺.不同血液检验指标在冠心病诊断中的应用分析[J].中国卫生标准管理,2017,8(19):123-124.
[9]张慧,张玉顺.冠心病患者血清胆红素与低密度脂蛋白胆固醇水平的关系研究[J].实用心脑肺血管病杂志,2015,23(3):47-48.
[2]曾春景.不同血液检验指标应用于冠心病患者中检验的价值探讨[J].临床医药文献电子杂志,2017,4(28):5478-5479.
[3]陈越.联合检测脂蛋白(a)和胆红素在冠心病诊断中的价值分析[J].特别健康,2017(24):50.
[4]熊智敏.常规血脂检验诊断冠心病的临床价值分析[J].基层医学论坛,2017,21(22):2976-2977.
[5]杨晓玲.血清胆红素检测与尿酸检验对诊断冠心病的临床价值分析[J].医药前沿,2018,8(8):39-40.
[6]乔小霞,陈碧,杨学茹.不同血液检验指标在冠心病患者诊断中的应用价值[J].中国保健营养,2017,27(35):379-380.
[7]杨菊.血清胆红素与尿酸检验对冠心病诊断的价值[J].东方食疗与保健,2017(9):258.
[8]徐贺.不同血液检验指标在冠心病诊断中的应用分析[J].中国卫生标准管理,2017,8(19):123-124.
[9]张慧,张玉顺.冠心病患者血清胆红素与低密度脂蛋白胆固醇水平的关系研究[J].实用心脑肺血管病杂志,2015,23(3):47-48.