安徽省2008-2017年恙虫病流行特征与重复感染分析
|
摘要
目的了解安徽省2008-2017年恙虫病流行特征,为制定防治策略和控制措施提供科学依据。方法采用描述流行病学方法对2008-2017年安徽省恙虫病病例进行描述分析。结果2008-2017年安徽省恙虫病整体发病呈上升趋势(X~2=3 522. 49,P <0. 001),2016年发病率最高为3. 98/10万;病例明显集中在9月份～11月份,属于典型的"秋冬型",10月达到高峰,具有"10月高发"现象;病例主要集中在40～79岁年龄段,占总报告病例数的76. 64%,60～69岁年龄段累计病例数最多,发病以农民为主。结论近年来,安徽省恙虫病发病整体呈上升趋势,需加强对重点地区恙虫病的日常监测工作和恙虫病病原检测工作,积极开展恙虫病的防治与健康教育工作。
Objective To understand the epidemiological characteristics of scrub typhus in Anhui Province from 2008 to 2017,so as to provide scientific evidence for the development of control strategies and control measures. Methods Descriptive epidemiological methods were used to describe and analyze the cases of scrub typhus in Anhui Province from 2008 to 2017. Results The overall incidence of scrub typhus in Anhui Province showed an upward trend from 2008 to 2017( x~2= 3 522. 49,P < 0. 001). The highest incidence rate in 2016 was 3. 98/100 000. The cases were concentrated from September to November. It was a typical"autumn and winter type"and peaked in October. It had the phenomenon of"high incidence in October"; the cases were mainly concentrated in the age group of 40-79 years old,accounting for 76. 64% of the total reported cases. The cumulative number of cases in the 60-69 age group was the largest,and the incidence was mainly farmers. Conclusions In recent years,the incidence of scrub typhus in Anhui Province has shown an upward trend. It is necessary to strengthen the routine monitoring of scrub typhus in key areas and the detection of scrub typhus pathogens,and actively carry out prevention and health education of scrub typhus.
Objective To understand the epidemiological characteristics of scrub typhus in Anhui Province from 2008 to 2017,so as to provide scientific evidence for the development of control strategies and control measures. Methods Descriptive epidemiological methods were used to describe and analyze the cases of scrub typhus in Anhui Province from 2008 to 2017. Results The overall incidence of scrub typhus in Anhui Province showed an upward trend from 2008 to 2017( x~2= 3 522. 49,P < 0. 001). The highest incidence rate in 2016 was 3. 98/100 000. The cases were concentrated from September to November. It was a typical"autumn and winter type"and peaked in October. It had the phenomenon of"high incidence in October"; the cases were mainly concentrated in the age group of 40-79 years old,accounting for 76. 64% of the total reported cases. The cumulative number of cases in the 60-69 age group was the largest,and the incidence was mainly farmers. Conclusions In recent years,the incidence of scrub typhus in Anhui Province has shown an upward trend. It is necessary to strengthen the routine monitoring of scrub typhus in key areas and the detection of scrub typhus pathogens,and actively carry out prevention and health education of scrub typhus.
引文
[1]Watt G,Parola P.Scrub typhus and tropical rickettsioses[J].Curr Opin Infect Dis,2003,16(5):429-436.DOI:10.1097/01.qco.0000092814.64370.70.
[2]Razak A,Sathyanarayanan V,Prabhu M,et al.Scrub typhus in Southern India:are we doing enough?[J].Trop Doct,2010,40(3):149-151.DOI:10.1258/td.2010.090508.
[3]张丽娟,付秀萍,范明远.我国立克次体研究与立克次体病的流行现状[J].热带病与寄生虫病学,2005,3(1):37-42.DOI:10.3969/j.issn.1672-2302.2005.01.016.Zhang LJ,Fu XP,Fan MY.The prevalence of rickettsia research and rickettsial disease in China[J].J Trop Dis Parasitol,2005,3(1):37-42.DOI:10.3969/j.issn.1672-2302.2005.01.016.
[4]夏胜利,申晓靖,邓文斌,等.河南省首次实验室证实恙虫病暴发疫情[J].中国媒介生物学及控制杂志,2007,18(3):230-233.DOI:10.3969/j.issn.1003-4692.2007.03.017.Xia SL,Shen XJ,Deng WB,et al.The lab identification on tsutsugamushi disease for the first outbreak in Henan province[J].Chin J Vector Bio&Control,2007,18(3):230-233.DOI:10.3969/j.issn.1003-4692.2007.03.017.
[5]上官致洋,吴斐琳,严秀英,等.2011-2015年抚州市恙虫病流行特征分析[J].中华疾病控制杂志,2018,22(2):153-156.DOI:10.16462/j.cnki.zhjbkz.2018.02.012.Shangguan ZY,Wu FL,Yan XY,et al.Analysis on the epidemiological characteristics of scrub typhus in Fuzhou from 2011 to2015[J].Chin J Dis Control Prev,2018,22(2):153-156.DOI:10.16462/j.cnki.zhjbkz.2018.02.012.
[6]展海燕,徐贞,何义林.江苏省靖江市2011-2015年恙虫病流行特征及影响因素[J].中华疾病控制杂志,2017,21(11):1119-1122.DOI:10.16462/j.cnki.zhjbkz.2017.11.010.Zhan HY,Xu Z,He YL.Epidemiological characteristics and influencing factors of scrub typhus in Jingjiang City,Jiangsu Province from 2011 to 2015[J].Chin J Dis Control Prev,2017,21(11):1119-1122.DOI:10.16462/j.cnki.zhjbkz.2017.11.010.
[7]龚健仁.我国恙虫病的分布状况与研究概况[J].中华疾病控制杂志,2016,20(11):1176-1181.DOI:10.16462/j.cnki.zhjbkz.2016.11.025.Gong JR.The distribution and research situation of scrub typhus in China[J].Chin J Dis Control Prev,2016,20(11):1176-1181.DOI:10.16462/j.cnki.zhjbkz.2016.11.025.
[8]姜仁杰,沈进进,张盐珠,等.盐城市2006年恙虫病爆发的流行病学调查[J].中华疾病控制杂志,2007,11(6):636-638.DOI:10.3969/j.issn.1674-3679.2007.06.030.Jang RJ,Shen JJ,Zhang YZ,et al.Epidemiological analysis of tsutsugamushi outbreaks in Yancheng City in 2006[J].Chin JDis Control Prev,2007,11(6):636-638.DOI:10.3969/j.issn.1674-3679.2007.06.030.
[9]吴家兵,胡岱霖,何凡,等.2008年安徽省阜阳市首起恙虫病暴发疫情的流行病学调查[J].中华疾病控制杂志,2009,13(6):651-653.Wu JB,Hu DL,He F,et al.Epidemiological analysis on the first outbreak of tsutsugamushi disease in Fuyang City of Anhui Province in 2008[J].Chin J Dis Control Prev,2009,13(6):651-653.
[10]汪茂荣,于乐成,何长伦,等.安徽地区一起恙虫病暴发流行的调查分析[J].中华实验和临床感染病杂志:电子版,2008,2(3):174-177.DOI:10.3969/j.issn.1674-1358.2008.03.008.Wang MR,Yu LC,He CL,et al.Epidemiological investigation on an outbreak of tsutsugamushi disease in Anhui Province[J].Chinese Journal of Experimental and Clinical Infectious Diseases(electronic version),2008,2(3):174-177.DOI:10.3969/j.issn.1674-1358.2008.03.008.
[11]吴光华.我国恙虫病流行病学研究现状与展望[J].中华传染病杂志,2000,18(2):142-144.DOI:10.3760/j.issn:1000-6680.2000.02.033.Wu GH.Current status and prospects of epidemiology research on scrub typhus in China[J].Chin J Infect Dis,2000,18(2):142-144.DOI:10.3760/j.issn:1000-6680.2000.02.033.
[12]余平,程慧健,魏雄杰.江西省2006-2012年恙虫病流行特征分析[J].中华疾病控制杂志,2014,18(11):1124.Yu P,Cheng HJ,Wei XJ.Epidemiological characteristics of scrub typhus in Jiangxi Province from 2006 to 2012[J].Chin JDis Control Prev,2014,18(11):1124.
[13]张育富,周明浩,刘大鹏,等.江苏沿海地区2005-2013年虫媒传染病流行特征[J].中国公共卫生,2015,31(1):36-39.DOI:10.11847/zgggws2015-31-01-11.Zhang YF,Zhou MH,Liu DP,et al.Epidemic characteristics of vector-borne diseases in coastal areas of Jiangsu Province,2005-2013[J].Chin J Public Health,2015,31(1):36-39.DOI:10.11847/zgggws2015-31-01-11.
[14]王铁强,姚云英,黄喜强,等.2006-2012年广东省恙虫病流行特征分析[J].中华地方病学杂志,2014,33(4):429-432.DOI:10.3760/cma.j.issn.2095-4255.2014.04.021.Wang TQ,Yao YY,Huang XQ,et al.Characteristics of scrub typhus epidemic in Guangdong Province from 2006 to 2012[J].Chin J Endemiol,2014,33(4):429-432.DOI:10.3760/cma.j.issn.2095-4255.2014.04.021.
[15]颜玉炳,郭志南,陈小平.厦门市恙虫病流行特征及发病趋势预测效果研究[J].中华卫生杀虫药械,2016,22(3):262-265.Yan YB,Guo ZN,Chen XP.Study on epidemiological characteristics and predicting effect of ascariasis in Xiamen City[J].Chinese Journal of Hygienic Insecticides&Equipments,2016,22(3):262-265.
[16]于昌军,刘运喜,李国兰,等.阜阳市疑似恙虫病患者和恙螨及恙虫病鼠类中东方体分离及基因分型研究[J].中华医院感染学杂志,2018,28(6):837-840.DOI:10.11816/cn.ni.2017-173943.Yu CJ,Liu YX,Li GL,et al.Orientia tsutsugamushi isolated from patients with suspected tsutsugamushi disease,chigger mites and mice with scrub typhus in Fuyang and genotypes[J].Chinese Journal of Nosocomiology,2018,28(6):837-840.DOI:10.11816/cn.ni.2017-173943.
[17]张守印,蒋德勇,俞东征.我国秋季型恙虫病地方特点及流行状况分析[J].国外医学(医学地理分册),2009,30(3):133-135.DOI:10.3969/j.issn.1001-8883.2009.03.010.Zhang SY,Jiang DY,Yu DZ.Endemic characteristics of autumn scrub typhus and the epidemic situation in China[J].Foreign Medical Sciences(section of medgeography),2009,30(3):133-135.DOI:10.3969/j.issn.1001-8883.2009.03.010.
[18]刘艳慧,李乔玄,景钦隆,等.广州市2006-2015年恙虫病疫情时空分布特征[J].中国媒介生物学及控制杂志,2017,28(4):336-339.DOI:10.11853/j.issn.1003.8280.2017.04.007.Liu YH,Li QX,Jing QL,et al.Spatiotemporal distribution of scrub typhus in Guangzhou,China from 2006 to 2015[J].Chin JVector Bio&Control,2017,28(4):336-339.DOI:10.11853/j.issn.1003.8280.2017.04.007.
[19]凌远理,陈晓燕.2007-2016年广州市海珠区恙虫病流行特征分析[J].华南预防医学,2018,44(2):141-143.DOI:10.13217/j.scjpm.2018.0141.Ling YL,Chen XY.Epidemiological characteristics of scrub typhus in Haizhu District of Guangzhou City from 2007 to 2016[J].South China J Prve Med,2018,44(2):141-143.DOI:10.13217/j.scjpm.2018.0141.
[20]邓小昭,许可,孔晶,等.汉坦病毒和恙虫病东方体复合感染的组织细胞培养研究[J].中华流行病学杂志,2006,27(6):518-521.DOI:10.3760/j.issn:0254-6450.2006.06.013.Deng XZ,Xu K,Kong J,et al.Study on the coinfection of Hantavirus and Orientia tsutsugamushi in tissue cell culture[J].Chin J Epidemiol,2006,27(6):518-521.DOI:10.3760/j.issn:0254-6450.2006.06.013.
[2]Razak A,Sathyanarayanan V,Prabhu M,et al.Scrub typhus in Southern India:are we doing enough?[J].Trop Doct,2010,40(3):149-151.DOI:10.1258/td.2010.090508.
[3]张丽娟,付秀萍,范明远.我国立克次体研究与立克次体病的流行现状[J].热带病与寄生虫病学,2005,3(1):37-42.DOI:10.3969/j.issn.1672-2302.2005.01.016.Zhang LJ,Fu XP,Fan MY.The prevalence of rickettsia research and rickettsial disease in China[J].J Trop Dis Parasitol,2005,3(1):37-42.DOI:10.3969/j.issn.1672-2302.2005.01.016.
[4]夏胜利,申晓靖,邓文斌,等.河南省首次实验室证实恙虫病暴发疫情[J].中国媒介生物学及控制杂志,2007,18(3):230-233.DOI:10.3969/j.issn.1003-4692.2007.03.017.Xia SL,Shen XJ,Deng WB,et al.The lab identification on tsutsugamushi disease for the first outbreak in Henan province[J].Chin J Vector Bio&Control,2007,18(3):230-233.DOI:10.3969/j.issn.1003-4692.2007.03.017.
[5]上官致洋,吴斐琳,严秀英,等.2011-2015年抚州市恙虫病流行特征分析[J].中华疾病控制杂志,2018,22(2):153-156.DOI:10.16462/j.cnki.zhjbkz.2018.02.012.Shangguan ZY,Wu FL,Yan XY,et al.Analysis on the epidemiological characteristics of scrub typhus in Fuzhou from 2011 to2015[J].Chin J Dis Control Prev,2018,22(2):153-156.DOI:10.16462/j.cnki.zhjbkz.2018.02.012.
[6]展海燕,徐贞,何义林.江苏省靖江市2011-2015年恙虫病流行特征及影响因素[J].中华疾病控制杂志,2017,21(11):1119-1122.DOI:10.16462/j.cnki.zhjbkz.2017.11.010.Zhan HY,Xu Z,He YL.Epidemiological characteristics and influencing factors of scrub typhus in Jingjiang City,Jiangsu Province from 2011 to 2015[J].Chin J Dis Control Prev,2017,21(11):1119-1122.DOI:10.16462/j.cnki.zhjbkz.2017.11.010.
[7]龚健仁.我国恙虫病的分布状况与研究概况[J].中华疾病控制杂志,2016,20(11):1176-1181.DOI:10.16462/j.cnki.zhjbkz.2016.11.025.Gong JR.The distribution and research situation of scrub typhus in China[J].Chin J Dis Control Prev,2016,20(11):1176-1181.DOI:10.16462/j.cnki.zhjbkz.2016.11.025.
[8]姜仁杰,沈进进,张盐珠,等.盐城市2006年恙虫病爆发的流行病学调查[J].中华疾病控制杂志,2007,11(6):636-638.DOI:10.3969/j.issn.1674-3679.2007.06.030.Jang RJ,Shen JJ,Zhang YZ,et al.Epidemiological analysis of tsutsugamushi outbreaks in Yancheng City in 2006[J].Chin JDis Control Prev,2007,11(6):636-638.DOI:10.3969/j.issn.1674-3679.2007.06.030.
[9]吴家兵,胡岱霖,何凡,等.2008年安徽省阜阳市首起恙虫病暴发疫情的流行病学调查[J].中华疾病控制杂志,2009,13(6):651-653.Wu JB,Hu DL,He F,et al.Epidemiological analysis on the first outbreak of tsutsugamushi disease in Fuyang City of Anhui Province in 2008[J].Chin J Dis Control Prev,2009,13(6):651-653.
[10]汪茂荣,于乐成,何长伦,等.安徽地区一起恙虫病暴发流行的调查分析[J].中华实验和临床感染病杂志:电子版,2008,2(3):174-177.DOI:10.3969/j.issn.1674-1358.2008.03.008.Wang MR,Yu LC,He CL,et al.Epidemiological investigation on an outbreak of tsutsugamushi disease in Anhui Province[J].Chinese Journal of Experimental and Clinical Infectious Diseases(electronic version),2008,2(3):174-177.DOI:10.3969/j.issn.1674-1358.2008.03.008.
[11]吴光华.我国恙虫病流行病学研究现状与展望[J].中华传染病杂志,2000,18(2):142-144.DOI:10.3760/j.issn:1000-6680.2000.02.033.Wu GH.Current status and prospects of epidemiology research on scrub typhus in China[J].Chin J Infect Dis,2000,18(2):142-144.DOI:10.3760/j.issn:1000-6680.2000.02.033.
[12]余平,程慧健,魏雄杰.江西省2006-2012年恙虫病流行特征分析[J].中华疾病控制杂志,2014,18(11):1124.Yu P,Cheng HJ,Wei XJ.Epidemiological characteristics of scrub typhus in Jiangxi Province from 2006 to 2012[J].Chin JDis Control Prev,2014,18(11):1124.
[13]张育富,周明浩,刘大鹏,等.江苏沿海地区2005-2013年虫媒传染病流行特征[J].中国公共卫生,2015,31(1):36-39.DOI:10.11847/zgggws2015-31-01-11.Zhang YF,Zhou MH,Liu DP,et al.Epidemic characteristics of vector-borne diseases in coastal areas of Jiangsu Province,2005-2013[J].Chin J Public Health,2015,31(1):36-39.DOI:10.11847/zgggws2015-31-01-11.
[14]王铁强,姚云英,黄喜强,等.2006-2012年广东省恙虫病流行特征分析[J].中华地方病学杂志,2014,33(4):429-432.DOI:10.3760/cma.j.issn.2095-4255.2014.04.021.Wang TQ,Yao YY,Huang XQ,et al.Characteristics of scrub typhus epidemic in Guangdong Province from 2006 to 2012[J].Chin J Endemiol,2014,33(4):429-432.DOI:10.3760/cma.j.issn.2095-4255.2014.04.021.
[15]颜玉炳,郭志南,陈小平.厦门市恙虫病流行特征及发病趋势预测效果研究[J].中华卫生杀虫药械,2016,22(3):262-265.Yan YB,Guo ZN,Chen XP.Study on epidemiological characteristics and predicting effect of ascariasis in Xiamen City[J].Chinese Journal of Hygienic Insecticides&Equipments,2016,22(3):262-265.
[16]于昌军,刘运喜,李国兰,等.阜阳市疑似恙虫病患者和恙螨及恙虫病鼠类中东方体分离及基因分型研究[J].中华医院感染学杂志,2018,28(6):837-840.DOI:10.11816/cn.ni.2017-173943.Yu CJ,Liu YX,Li GL,et al.Orientia tsutsugamushi isolated from patients with suspected tsutsugamushi disease,chigger mites and mice with scrub typhus in Fuyang and genotypes[J].Chinese Journal of Nosocomiology,2018,28(6):837-840.DOI:10.11816/cn.ni.2017-173943.
[17]张守印,蒋德勇,俞东征.我国秋季型恙虫病地方特点及流行状况分析[J].国外医学(医学地理分册),2009,30(3):133-135.DOI:10.3969/j.issn.1001-8883.2009.03.010.Zhang SY,Jiang DY,Yu DZ.Endemic characteristics of autumn scrub typhus and the epidemic situation in China[J].Foreign Medical Sciences(section of medgeography),2009,30(3):133-135.DOI:10.3969/j.issn.1001-8883.2009.03.010.
[18]刘艳慧,李乔玄,景钦隆,等.广州市2006-2015年恙虫病疫情时空分布特征[J].中国媒介生物学及控制杂志,2017,28(4):336-339.DOI:10.11853/j.issn.1003.8280.2017.04.007.Liu YH,Li QX,Jing QL,et al.Spatiotemporal distribution of scrub typhus in Guangzhou,China from 2006 to 2015[J].Chin JVector Bio&Control,2017,28(4):336-339.DOI:10.11853/j.issn.1003.8280.2017.04.007.
[19]凌远理,陈晓燕.2007-2016年广州市海珠区恙虫病流行特征分析[J].华南预防医学,2018,44(2):141-143.DOI:10.13217/j.scjpm.2018.0141.Ling YL,Chen XY.Epidemiological characteristics of scrub typhus in Haizhu District of Guangzhou City from 2007 to 2016[J].South China J Prve Med,2018,44(2):141-143.DOI:10.13217/j.scjpm.2018.0141.
[20]邓小昭,许可,孔晶,等.汉坦病毒和恙虫病东方体复合感染的组织细胞培养研究[J].中华流行病学杂志,2006,27(6):518-521.DOI:10.3760/j.issn:0254-6450.2006.06.013.Deng XZ,Xu K,Kong J,et al.Study on the coinfection of Hantavirus and Orientia tsutsugamushi in tissue cell culture[J].Chin J Epidemiol,2006,27(6):518-521.DOI:10.3760/j.issn:0254-6450.2006.06.013.