异基因造血干细胞移植治疗慢性活动性EB病毒感染患者的护理
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摘要
目的总结异基因造血干细胞移植治疗成人慢性活动性EB病毒感染的护理经验。方法回顾性分析7例成人慢性活动性EB病毒感染患者异基因造血干细胞移植的治疗及护理方法。结果 5例患者获得完全缓解,2例死亡。结论慢性活动性EB病毒感染患者病情严重,治疗难度大且预后不佳,异基因造血干细胞移植可改善患者预后。做好患者治疗期间的情绪管理、症状管理及并发症防护是护理的关键。
引文
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[8] 廖艳华,徐金环,关军,等.造血干细胞移植相关血栓性微血管病2例报道并文献复习[J].内科急危重症杂志,2016,22(1):74-76.
[9] 王晓靖,白海.1例HLA半相合造血干细胞与MSC共移植治疗SAA的护理[J].护理学杂志,2008,23(15):75-76.
[10] 于迪,韩雅慧,扈臣媛,等.异基因造血干细胞移植后慢性肝脏移植物抗宿主病的危险因素及预后分析[J].中国实验血液学杂志,2018,26(4):1174-1179.
[11] 王晓宁,孙春红,郭彩利,等.急性白血病半相合外周血造血干细胞移植后发生单纯肠道aGVHD 的影响因素及治疗转归[J].中国实验血液学杂志,2017,25(3):880-884.
[12] 徐丽,万滢,张良满.3例造血干细胞移植术后并发重度肠道移植物抗宿主病患者的护理[J].护理学杂志,2007,22(23):58-59.
[13] 刘颖,钟册俊,黄亮,等.成人慢性活动性EB病毒感染2例报道并文献复习[J].中国感染与化疗杂志,2016,16(1):41-44.
[2] 卢家桀,徐缓,唐红.慢性活动性EB病毒感染进展为大B细胞淋巴瘤1例报告[J].四川大学学报(医学版),2014,45(1):163.
[3] Arai A,Imadome K,Wang L,et al.Recurrence of chronic active Epstein-Barr virus infection from donor cells after achieving complete response through allogeneic bone marrow transplantation[J].Intern Med,2012,51(7):777-782.
[4] Kimura H,Hoshino Y,Kanegane H,et al.Clinical and virologic characteristics of chronic active Epstein-Barr virus infection[J].Blood,2001,98(2):280-286.
[5] Rosenthal J.Hematopoietic cell transplantation-associa-ted thrombotic microangiopathy:a review of pathophysiology,diagnosis,and treatment[J].J Blood Med,2016,7:181-186.
[6] Nishida T,Hamaguchi M,Hirabayashi N,et al.Intestinal thrombotic microangiopathy after allogeneic bone marrow transplantation:a clinical imitator of acute enteric graft-versus-host disease[J].Bone Marrow Transplant,2004,30(6):709-715.
[7] Uderzo C,Fumagalli M,De Lorenzo P,et al.Impact of thrombotic thrombocytopenic purpura on leukemic children undergoing bone marrow transplantation[J].Bone Marrow Transplant,2000,26(9):1005-1009.
[8] 廖艳华,徐金环,关军,等.造血干细胞移植相关血栓性微血管病2例报道并文献复习[J].内科急危重症杂志,2016,22(1):74-76.
[9] 王晓靖,白海.1例HLA半相合造血干细胞与MSC共移植治疗SAA的护理[J].护理学杂志,2008,23(15):75-76.
[10] 于迪,韩雅慧,扈臣媛,等.异基因造血干细胞移植后慢性肝脏移植物抗宿主病的危险因素及预后分析[J].中国实验血液学杂志,2018,26(4):1174-1179.
[11] 王晓宁,孙春红,郭彩利,等.急性白血病半相合外周血造血干细胞移植后发生单纯肠道aGVHD 的影响因素及治疗转归[J].中国实验血液学杂志,2017,25(3):880-884.
[12] 徐丽,万滢,张良满.3例造血干细胞移植术后并发重度肠道移植物抗宿主病患者的护理[J].护理学杂志,2007,22(23):58-59.
[13] 刘颖,钟册俊,黄亮,等.成人慢性活动性EB病毒感染2例报道并文献复习[J].中国感染与化疗杂志,2016,16(1):41-44.