新生儿颅内出血的危险因素分析
|
摘要
目的:探讨笔者所在医院120例新生儿颅内出血的相关危险因素。方法:采用回顾性研究方法选取笔者所在医院近2010年9月-2018年9月新生儿科颅内出血患儿120例,以同期产科出生正常新生儿120例作为对照研究,采用单因素分析和多因素Logistic回归分析方法进行新生儿颅内出血的相关危险因素研究。结果:多因素Logistic回归分析显示巨大儿、早产、窒息、脐带绕颈、羊水污染为颅内出血主要危险因素(P<0.05)。结论:新生儿颅内出血与围生期缺氧缺血、产伤关系密切,加强围生期保健工作,提高接生质量是降低颅内出血的重要因素。
Objective:To explore the risk factors of intracranial hemorrhage in 120 neonates in our hospital.Method:A retrospective study was performed to select 120 cases of intracranial hemorrhage in neonatology in our hospital from 2010 to 2018,and 120 cases of normal neonates were used as a control study in the same period.Univariate analysis and multivariate logistic regression analysis were used.Result:Multivariate logistic regression analysis showed that macrosomia,preterm birth,asphyxia,umbilical cord around neck,amniotic fluid were the main risk factors for intracranial hemorrhage(P<0.05).Conclusion:Neonatal intracranial hemorrhage is closely related to perinatal ischemia,hypoxia and birth injury.Strengthening peripartum health care and improving delivery quality are important factors to reduce intracranial hemorrhage.
Objective:To explore the risk factors of intracranial hemorrhage in 120 neonates in our hospital.Method:A retrospective study was performed to select 120 cases of intracranial hemorrhage in neonatology in our hospital from 2010 to 2018,and 120 cases of normal neonates were used as a control study in the same period.Univariate analysis and multivariate logistic regression analysis were used.Result:Multivariate logistic regression analysis showed that macrosomia,preterm birth,asphyxia,umbilical cord around neck,amniotic fluid were the main risk factors for intracranial hemorrhage(P<0.05).Conclusion:Neonatal intracranial hemorrhage is closely related to perinatal ischemia,hypoxia and birth injury.Strengthening peripartum health care and improving delivery quality are important factors to reduce intracranial hemorrhage.
引文
[1]罗香团,陆月凤.新生儿颅内出血的相关因素分析及预防[J].广西医学,2013,35(12):1668-1669.
[2]秦静.足月新生儿颅内出血的高危因素分析及防治.[J].医学信息,2011,24(1):359-360.
[3]赵晓君,刘锟,周忠洁,等.磁敏感加权成像在新生儿颅内出血的诊断价值及早产儿与足月儿间的对比研究[J].中华全科医学,2017,15(2):188-191.
[4]Uehara E,Nakao H.Slow Elevation in Protein C Activity without a PROCMutation in a Neonate with Intracranial Hemorrhage[J].AJP Rep,2018,8(2):68-70.
[5]李翠莲.美洛培南在新生儿颅内出血并发化脓性脑膜炎治疗中的应用[J].中国处方药,2016,14(10):65-66.
[6]Tan A P,Svrckova P.Intracranial hemorrhage in neonates:A review of etiologies,patterns and predicted clinical outcomes[J].Eur J Paediatr Neurol,2018,22(4):690-717.
[7]何冬慧.颅内出血新生儿血清IL-6、TNF-α动态变化对判断预后的临床价值[J].现代中西医结合杂志,2016,25(2):179-181.
[8]Phan K,Moore J M,Griessenauer C J,et al.Aspirin and Risk of Subarachnoid Hemorrhage:Systematic Review and Meta-Analysis[J].Stroke,2017,48(5):1210-1217.
[9]赵晓君,刘锟,周忠洁,等.磁敏感加权成像在新生儿颅内出血的诊断价值及早产儿与足月儿间的对比研究[J].中华全科医学,2017,15(2):188-191,209.
[10]李翠莲.美洛培南在新生儿颅内出血并发化脓性脑膜炎治疗中的应用[J].中国处方药,2016,14(10):65-66.
[11]Bashir A,Mikkelsen R,S?rensen L,et al.Non-aneurysmal subarachnoid hemorrhage:When is a second angiography indicated?[J].Neuroradiol J,2018,31(3):244-252.
[12]Delgado A F,Jiménez G E,Bravo R,et al.Intracranial stents in the endovascular treatment of acute ischemic stroke[J].Radiologia,2017,59(3):218-225.
[2]秦静.足月新生儿颅内出血的高危因素分析及防治.[J].医学信息,2011,24(1):359-360.
[3]赵晓君,刘锟,周忠洁,等.磁敏感加权成像在新生儿颅内出血的诊断价值及早产儿与足月儿间的对比研究[J].中华全科医学,2017,15(2):188-191.
[4]Uehara E,Nakao H.Slow Elevation in Protein C Activity without a PROCMutation in a Neonate with Intracranial Hemorrhage[J].AJP Rep,2018,8(2):68-70.
[5]李翠莲.美洛培南在新生儿颅内出血并发化脓性脑膜炎治疗中的应用[J].中国处方药,2016,14(10):65-66.
[6]Tan A P,Svrckova P.Intracranial hemorrhage in neonates:A review of etiologies,patterns and predicted clinical outcomes[J].Eur J Paediatr Neurol,2018,22(4):690-717.
[7]何冬慧.颅内出血新生儿血清IL-6、TNF-α动态变化对判断预后的临床价值[J].现代中西医结合杂志,2016,25(2):179-181.
[8]Phan K,Moore J M,Griessenauer C J,et al.Aspirin and Risk of Subarachnoid Hemorrhage:Systematic Review and Meta-Analysis[J].Stroke,2017,48(5):1210-1217.
[9]赵晓君,刘锟,周忠洁,等.磁敏感加权成像在新生儿颅内出血的诊断价值及早产儿与足月儿间的对比研究[J].中华全科医学,2017,15(2):188-191,209.
[10]李翠莲.美洛培南在新生儿颅内出血并发化脓性脑膜炎治疗中的应用[J].中国处方药,2016,14(10):65-66.
[11]Bashir A,Mikkelsen R,S?rensen L,et al.Non-aneurysmal subarachnoid hemorrhage:When is a second angiography indicated?[J].Neuroradiol J,2018,31(3):244-252.
[12]Delgado A F,Jiménez G E,Bravo R,et al.Intracranial stents in the endovascular treatment of acute ischemic stroke[J].Radiologia,2017,59(3):218-225.