磁共振常规平扫联合扩散加权成像和动态增强检查诊断子宫内膜癌的应用
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摘要
目的探讨磁共振常规平扫联合扩散加权成像和动态增强检查诊断子宫内膜癌的应用价值。方法选取2012年1月~2017年7月本院的50例子宫内膜癌患者,随机分为研究组与对照组,各25例。对照组进行磁共振(MRI)常规平扫和动态增强(DCE)检查;研究组,在常规平扫基础上,联合扩散加权成像(DWI)和动态增强(DCE)检查,对比两组患者检查结果。结果 50例患者,11例Ⅰa期,9例患者Ⅰb期,16例Ⅱ期,10例Ⅲ期,4例Ⅳ期。研究组子宫内膜癌诊断敏感性、特异性、符合率分别为91.6%、84.6%、88.0%,对照组分别为76.9%、58.3%、68.0%,研究组明显高于对照组,差异显著,具有统计学意义(P<0.05)。结论子宫内膜癌临床诊断中,以磁共振常规平扫为基础,联合DWI和DCE检查,诊断准确率高,效果显著,值得广泛推广。
Objective To explore the application value of the magnetic resonance diffusion weighted imaging combined with conventional unenhanced and dynamic enhanced examination in the diagnosis of endometrial carcinoma. Methods 50 patients with endometrial cancer,who were referred to our hospital from January 2012 to July 2017 year,were selected and randomly divided into study group and control group,with 25 cases in each group. The patients in the control group underwent magnetic resonance( MRI) and dynamic contrast-enhanced( DCE) examination,while,the patients in the study group,in addition to be subjected to routine plain scan,underwent the diffusion weighted imaging( DWI) combined with dynamic contrast-enhanced( DCE) examination. Then,results were compared between two groups. Results Among those 50 patients,there were 11 cases of stage Ⅰa,9 cases of stageⅠb,16 cases of stageⅡ,10 cases of stage III,4 cases of stage Ⅳ. At the same time,of uterine endometrial cancer diagnostic sensitivity,specificity and accuracy in the research group were 91. 6%,84. 6%,88%,while,those in the control group were 76. 9%,58. 3%,68%. Those in the study group were significantly higher than in the control group and the differences were statistically significant( P < 0. 05). Conclusion In the clinical the diagnosis of endometrial carcinoma,on the basis of conventional plain magnetic resonance scan,the diffusion weighted imaging combined with dynamic contrast-enhanced examination has the higher diagnostic accuracy and the significant effect,which is worthy of popularization.
Objective To explore the application value of the magnetic resonance diffusion weighted imaging combined with conventional unenhanced and dynamic enhanced examination in the diagnosis of endometrial carcinoma. Methods 50 patients with endometrial cancer,who were referred to our hospital from January 2012 to July 2017 year,were selected and randomly divided into study group and control group,with 25 cases in each group. The patients in the control group underwent magnetic resonance( MRI) and dynamic contrast-enhanced( DCE) examination,while,the patients in the study group,in addition to be subjected to routine plain scan,underwent the diffusion weighted imaging( DWI) combined with dynamic contrast-enhanced( DCE) examination. Then,results were compared between two groups. Results Among those 50 patients,there were 11 cases of stage Ⅰa,9 cases of stageⅠb,16 cases of stageⅡ,10 cases of stage III,4 cases of stage Ⅳ. At the same time,of uterine endometrial cancer diagnostic sensitivity,specificity and accuracy in the research group were 91. 6%,84. 6%,88%,while,those in the control group were 76. 9%,58. 3%,68%. Those in the study group were significantly higher than in the control group and the differences were statistically significant( P < 0. 05). Conclusion In the clinical the diagnosis of endometrial carcinoma,on the basis of conventional plain magnetic resonance scan,the diffusion weighted imaging combined with dynamic contrast-enhanced examination has the higher diagnostic accuracy and the significant effect,which is worthy of popularization.
引文
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[8]黄恩善,韦寅,李瑞雄,等.ADC差值法鉴别乳腺良恶性病变价值研究[J].中国临床新医学,2016,9(11):1021-1024.
[9]Kierans AS,Bennett GL,Haghighi MA.Utility ofconventional and diffusion-weighted MRI features in distinguishing benign from malignant endometrial lesions[J].Eur J Radiol,2014,83(4):726-732.
[10]王关顺,飞勇,董兴祥,等.DWI结合高分辨T2WI磁共振在子宫内膜癌分期中的价值[J].放射学实践,2012,27(6):652-656.
[11]Zheng L,Zheng S,Yuan X,et al.Comparison of dynamic contrast-enhanced magnetic resonance imaging with T2-weighted imaging for preoperative staging of early endometrial carcinoma[J].Onco Targets ther,2015,17(8):1743-1751.
[2]陈作泉.术中快速冰冻病理检查诊断子宫内膜癌的价值探究[J].现代诊断与治疗,2015,26(2):289-291.
[3]段早辉,肖新兰,金明根,等.磁共振弥散加权成像在子宫内膜癌的初步研究[J].实用放射学杂志,2012,28(1):69-84.
[4]李文清.DWI联合MRI常规序列对早期子宫内膜癌术前评估的价值[J].医学影像学杂志,2014,24(5):809-815.
[5]王琨华.正常子宫内膜和子宫内膜癌的扩散加权成像特点[J].医学影像学杂志,2012,22(3):440-444.
[6]高明,刘庆余,蒋伟,等.动态增强MRI在子宫内膜癌术前分期中的应用[J].中国医学影像技术,2012,28(11):2060-2063.
[7]相世峰,邱乾德,张淑平.DWI和高分辨率T2WI结合在子宫内膜癌诊断和分期中的价值[J].医学影像学杂志,2012,22(6):976-979.
[8]黄恩善,韦寅,李瑞雄,等.ADC差值法鉴别乳腺良恶性病变价值研究[J].中国临床新医学,2016,9(11):1021-1024.
[9]Kierans AS,Bennett GL,Haghighi MA.Utility ofconventional and diffusion-weighted MRI features in distinguishing benign from malignant endometrial lesions[J].Eur J Radiol,2014,83(4):726-732.
[10]王关顺,飞勇,董兴祥,等.DWI结合高分辨T2WI磁共振在子宫内膜癌分期中的价值[J].放射学实践,2012,27(6):652-656.
[11]Zheng L,Zheng S,Yuan X,et al.Comparison of dynamic contrast-enhanced magnetic resonance imaging with T2-weighted imaging for preoperative staging of early endometrial carcinoma[J].Onco Targets ther,2015,17(8):1743-1751.