肝癌栓塞术后疼痛患者择时给药时间点的改进及效果
|
摘要
目的探讨择时给药时间点的改进在肝癌栓塞术后疼痛患者中的应用效果。方法将160例肝癌栓塞术后患者,按随机数字表法分为试验组80例和对照组80例。试验组每日给药时间为15:00和21:00;对照组每日给药时间为09:00和15:00。记录用药后24 h内不同时段的疼痛强度,及疼痛控制满意度。结果应用择时给药时间点后,患者的疼痛强度下降(P<0.05);患者疼痛控制满意度明显提高(P<0.05)。结论按择时给药时间点给药,有助于肝栓塞术后患者疼痛管理。
Objective To explore the effects of improvement in timing of medication administration in patients with pain after liver cancer embolization. Methods A total of 160 patients underwent liver cancer embolization were divided into the intervention group and the control group according to random number table method with 80 cases in each group. In the intervention group,the daily medication administration time was set at 15:00 and 21:00,the time was set at 9:00 and 15:00 for the control group. The incidence of pain occurred in different time periods within 24 hours and pain control satisfaction after liver cancer embolization were recorded. Results Incidence of pain decreased in the intervention group(P<0.05),satisfaction of pain control was significantly improved in the intervention group(P<0.05). Conclusion Improvement in timing of medication administration is helpful for pain management in patients after liver cancer embolization.
Objective To explore the effects of improvement in timing of medication administration in patients with pain after liver cancer embolization. Methods A total of 160 patients underwent liver cancer embolization were divided into the intervention group and the control group according to random number table method with 80 cases in each group. In the intervention group,the daily medication administration time was set at 15:00 and 21:00,the time was set at 9:00 and 15:00 for the control group. The incidence of pain occurred in different time periods within 24 hours and pain control satisfaction after liver cancer embolization were recorded. Results Incidence of pain decreased in the intervention group(P<0.05),satisfaction of pain control was significantly improved in the intervention group(P<0.05). Conclusion Improvement in timing of medication administration is helpful for pain management in patients after liver cancer embolization.
引文
[1]许秀芳,李晓蓉,刘玉金.肿瘤介入护理学[M].北京:科学出版社,2011:54-55.
[2]罗君,邵国良,郑家平,等.原发性肝癌肝动脉化疗栓塞术后腹痛的发生规律及影响因素[J].介入放射学杂志,2017,26(7):613-617.
[3]Chan S,Zhang L,Rowbottom L,et al.Effects of circadian rhythms and treatment times on the response of radiotherapy for painful bone metastases[J].Ann Palliat Med,2017,6(1):14-25.
[4]贺前勇,金风,李媛媛,等.生物钟基因Bmal1与时辰治疗在恶性肿瘤中的研究进展[J].中国肿瘤,2016,25(4):290-296.
[5]郭萍,杨东.时辰药理学在服药时间上的具体应用及药效学影响[J].中国临床医生杂志,2016,44(21):26-28.
[6]余早勤,张程亮,王友群,等.疼痛的昼夜节律与镇痛药物治疗[J].医药导报,2014,33(6):771-774.
[7]Boom M,Grefkens J,Olofsen E.Opioid chronopharmacology:influence of timing of infusion on fentanyl's analgesic efficacy in healthy human volunteers[J].J Pain Res,2010,21(3):183-190.
[8]何双亮,涂青,甘建辉,等.羟考酮注射液联合氟比洛芬酯用于乳腺癌改良根治术后患者镇痛的临床效果[J].临床和实验医学杂志,2018,17(12):1329-1332.
[9]成燕,童莺歌,刘敏君.术后活动性疼痛护理评估对疼痛管理质量的影响[J].中华护理杂志,2015,50(8):924-928.
[10]沈曲,李峥.休斯顿疼痛情况调查表信度和效度的研究[J].中华护理杂志,2006,41(11):1049-1051.
[12]赵中伟,纪建松,邵国良.肝动脉化疗栓塞联合射频消融治疗包膜下肝癌的疗效和安全性[J].中华放射学杂志,2016,50(5):380-383.
[13]沈曲,李峥,Gwen S,et al.手术后患者疼痛控制满意度状况及影响因素的研究[J].中华护理杂志,2007,42(3):197-201.
[2]罗君,邵国良,郑家平,等.原发性肝癌肝动脉化疗栓塞术后腹痛的发生规律及影响因素[J].介入放射学杂志,2017,26(7):613-617.
[3]Chan S,Zhang L,Rowbottom L,et al.Effects of circadian rhythms and treatment times on the response of radiotherapy for painful bone metastases[J].Ann Palliat Med,2017,6(1):14-25.
[4]贺前勇,金风,李媛媛,等.生物钟基因Bmal1与时辰治疗在恶性肿瘤中的研究进展[J].中国肿瘤,2016,25(4):290-296.
[5]郭萍,杨东.时辰药理学在服药时间上的具体应用及药效学影响[J].中国临床医生杂志,2016,44(21):26-28.
[6]余早勤,张程亮,王友群,等.疼痛的昼夜节律与镇痛药物治疗[J].医药导报,2014,33(6):771-774.
[7]Boom M,Grefkens J,Olofsen E.Opioid chronopharmacology:influence of timing of infusion on fentanyl's analgesic efficacy in healthy human volunteers[J].J Pain Res,2010,21(3):183-190.
[8]何双亮,涂青,甘建辉,等.羟考酮注射液联合氟比洛芬酯用于乳腺癌改良根治术后患者镇痛的临床效果[J].临床和实验医学杂志,2018,17(12):1329-1332.
[9]成燕,童莺歌,刘敏君.术后活动性疼痛护理评估对疼痛管理质量的影响[J].中华护理杂志,2015,50(8):924-928.
[10]沈曲,李峥.休斯顿疼痛情况调查表信度和效度的研究[J].中华护理杂志,2006,41(11):1049-1051.
[12]赵中伟,纪建松,邵国良.肝动脉化疗栓塞联合射频消融治疗包膜下肝癌的疗效和安全性[J].中华放射学杂志,2016,50(5):380-383.
[13]沈曲,李峥,Gwen S,et al.手术后患者疼痛控制满意度状况及影响因素的研究[J].中华护理杂志,2007,42(3):197-201.