不同程度寻常痤疮患者马拉色菌带菌率分析
|
摘要
目的研究不同程度寻常痤疮患者马拉色菌带菌率情况。方法选取2018年1月～6月于我科门诊就诊的寻常痤疮患者285例作为研究对象,取面部皮损分泌物涂片,然后在油镜下直接镜检。结果痤疮患者马拉色菌带菌率较高,中重度痤疮患者马拉色菌带菌率明显高于轻度痤疮患者,马拉色菌带菌率与性别及年龄无明显相关性。结论马拉色菌带菌率与痤疮病情明显相关,临床上应重视马拉色菌的检查。
Objective To study the infection rate of Malassezia in acne patients of different degrees.Methods285 patients with acne were collected from January 2018 to June 2018.The facial secretions were smeared and then examined under oil microscopy.Results Acne patients have a high rate of Malassezia infection.Malassezia infection rate were significantly higher in patients with moderate to severe acne than in patients with mild acne.Malassezia infection rate had no significant correlation with sex and age.Conclusion Malassezia infection rate is significantly correlated with acne.Clinical examination of Malassezia should be emphasized.
Objective To study the infection rate of Malassezia in acne patients of different degrees.Methods285 patients with acne were collected from January 2018 to June 2018.The facial secretions were smeared and then examined under oil microscopy.Results Acne patients have a high rate of Malassezia infection.Malassezia infection rate were significantly higher in patients with moderate to severe acne than in patients with mild acne.Malassezia infection rate had no significant correlation with sex and age.Conclusion Malassezia infection rate is significantly correlated with acne.Clinical examination of Malassezia should be emphasized.
引文
[1]Aktan S,Ozmen E,Sanli B.Anxiety,depression,and nature of acne vulgaris in adolescents[J].International Journal of Dermatology,2000,39(5):354-357.
[2]Kurokawa I,Danby F W,Ju Q,et al.New developments in our understanding of acne pathogenesis and treatment[J].Experimental Dermatology,2010,18(10):821-832.
[3]翟婉芳,唐先发,杨森.皮肤微生物多样性与相关疾病研究进展[J].中国麻风皮肤病杂志,2018,34(4):241-245.
[4]高峰,胡素泉,李智华,等.176例寻常痤疮患者马拉色菌带菌率的调查分析[J].中华皮肤科杂志,2004(8):54.
[5]张小军,陈丽梅.187例青少年寻常痤疮合并糠秕孢子菌感染临床分析[J].中国热带医学,2008(5):791-792.
[6]尹斌,冉玉平.马拉色菌临床鉴定研究进展[J].中华皮肤科杂志,2014,47(12):912-914.
[7]朱纹懿,刘金菊,李艳,等.微生物与痤疮发病的研究进展[J].皮肤病与性病,2017,39(5):332-335.
[8]Thomas DS,Ingham E,Bojar RA,et al.In vitro modulation of human keratinocyte pro-and anti-inflammatory cytokine production by the capsule of Malassezia species[J].Pathogens&Disease,2010,54(2):203-214.
[9]Akaza N,Akamatsu H,Numata S,et al.Microorganisms inhabiting follicular contents of facial acne are not only Propionibacterium but also Malassezia spp.[J].The Journal of Dermatology,2016,43(8):6.
[10]钱江,陈清华,刘永祥,等.难治性寻常型痤疮合并糠秕孢子菌及螨虫感染的临床观察[J].中国美容医学,2003(1):35-36.
[11]王际童,吕简承.中重度寻常痤疮合并糠秕孢子菌感染的临床研究[J].岭南皮肤性病科杂志,2004(3):258-259.
[12]傅琳玲,曹双林,蔡恒骥,等.青少年面部难治性痤疮马拉色菌检查及治疗[J].中国麻风皮肤病杂志,2011,27(10):744-745.
[13]蒙秉新,苏建英.面部痤疮皮损内糠秕马拉色菌检测及酮康唑治疗效果观察[J].中国热带医学,2003,3(4):468-469.
[14]石磊,李欣,王秀丽,等.痤疮合并马拉色菌毛囊炎28例临床分析[J].中国皮肤性病学杂志,2010,24(11):1066-1067.
[15]戚欣雨,胡永轩.马拉色菌感染的光学治疗研究进展[J].中国真菌学杂志,2018,13(5):318-320.
[2]Kurokawa I,Danby F W,Ju Q,et al.New developments in our understanding of acne pathogenesis and treatment[J].Experimental Dermatology,2010,18(10):821-832.
[3]翟婉芳,唐先发,杨森.皮肤微生物多样性与相关疾病研究进展[J].中国麻风皮肤病杂志,2018,34(4):241-245.
[4]高峰,胡素泉,李智华,等.176例寻常痤疮患者马拉色菌带菌率的调查分析[J].中华皮肤科杂志,2004(8):54.
[5]张小军,陈丽梅.187例青少年寻常痤疮合并糠秕孢子菌感染临床分析[J].中国热带医学,2008(5):791-792.
[6]尹斌,冉玉平.马拉色菌临床鉴定研究进展[J].中华皮肤科杂志,2014,47(12):912-914.
[7]朱纹懿,刘金菊,李艳,等.微生物与痤疮发病的研究进展[J].皮肤病与性病,2017,39(5):332-335.
[8]Thomas DS,Ingham E,Bojar RA,et al.In vitro modulation of human keratinocyte pro-and anti-inflammatory cytokine production by the capsule of Malassezia species[J].Pathogens&Disease,2010,54(2):203-214.
[9]Akaza N,Akamatsu H,Numata S,et al.Microorganisms inhabiting follicular contents of facial acne are not only Propionibacterium but also Malassezia spp.[J].The Journal of Dermatology,2016,43(8):6.
[10]钱江,陈清华,刘永祥,等.难治性寻常型痤疮合并糠秕孢子菌及螨虫感染的临床观察[J].中国美容医学,2003(1):35-36.
[11]王际童,吕简承.中重度寻常痤疮合并糠秕孢子菌感染的临床研究[J].岭南皮肤性病科杂志,2004(3):258-259.
[12]傅琳玲,曹双林,蔡恒骥,等.青少年面部难治性痤疮马拉色菌检查及治疗[J].中国麻风皮肤病杂志,2011,27(10):744-745.
[13]蒙秉新,苏建英.面部痤疮皮损内糠秕马拉色菌检测及酮康唑治疗效果观察[J].中国热带医学,2003,3(4):468-469.
[14]石磊,李欣,王秀丽,等.痤疮合并马拉色菌毛囊炎28例临床分析[J].中国皮肤性病学杂志,2010,24(11):1066-1067.
[15]戚欣雨,胡永轩.马拉色菌感染的光学治疗研究进展[J].中国真菌学杂志,2018,13(5):318-320.