VTIQ新技术定量检测正常大鼠肾脏实质与集合系统的价值
|
摘要
目的研究VTIQ新技术在定量检测大鼠肾脏实质与集合系统中的价值。方法选取40只正常雄性大鼠,根据体重的不同分为低体重组和高体重组,每组各20只,应用VTIQ新技术测量正常大鼠肾脏实质及集合系统的剪切波速度值(Vs)并进行比较,分析不同侧别和体重对Vs值的影响。结果不同侧别、体重的正常大鼠肾实质、集合系统同一部位的Vs值差异无统计学意义(P>0.05)。正常大鼠肾实质与肾集合系统之间的Vs值差异有统计学意义(P<0.05)。结论 VTIQ新技术可以定量反映正常大鼠肾脏实质与集合系统弹性系数的差异,可为进一步深入研究各种肾脏疾病提供一种全新、无创、定量的检测手段。
Objective To study the value of VTIQ in quantitatively detecting renal parenchyma and collection system in rats. Methods Forty normal male rats were selected and divided into low body weight group and high body weight group according to their weight, twenty rats in each group. The shear wave velocity values(Vs) of the renal parenchyma and collection system of normal rats were measured and compared, using the new VTIQ technology to analyze the influence of different sides and body weight on Vs values. Results There was no significant difference in the Vs values of the renal parenchyma and the same part of the collecting system of normal rats with different lateral groups and weights(P>0.05). There were statistically significant differences in Vs values between the renal parenchyma and the renal collecting system in normal rats(P<0.05).Conclusion The new VTIQ technique can provide a new, non-invasive and quantitative detection method for further study of various renal diseases by quantitatively differentiating the elastic coefficient of renal parenchyma and the aggregate system in normal rats
Objective To study the value of VTIQ in quantitatively detecting renal parenchyma and collection system in rats. Methods Forty normal male rats were selected and divided into low body weight group and high body weight group according to their weight, twenty rats in each group. The shear wave velocity values(Vs) of the renal parenchyma and collection system of normal rats were measured and compared, using the new VTIQ technology to analyze the influence of different sides and body weight on Vs values. Results There was no significant difference in the Vs values of the renal parenchyma and the same part of the collecting system of normal rats with different lateral groups and weights(P>0.05). There were statistically significant differences in Vs values between the renal parenchyma and the renal collecting system in normal rats(P<0.05).Conclusion The new VTIQ technique can provide a new, non-invasive and quantitative detection method for further study of various renal diseases by quantitatively differentiating the elastic coefficient of renal parenchyma and the aggregate system in normal rats
引文
[1] Li DD,Xu HX,Guo LH,et al.Combination of two-dimensional shear wave elastography with ultrasound breast imaging reporting and data system in the diagnosis of breast lesions:a new method to increase the diagnostic performance[J].Eur Radiol,2016,26(9):3290-3300.
[2] He YP,Xu HX,Li XL,et al.Comparison of Virtual Touch Tissue Imaging & Quantification (VTIQ) and Toshiba shear wave elastography (T-SWE) in diagnosis of thyroid nodules:Initial experience[J].Clin Hemorheol Microcirc,2017,66(1):15-26.
[3] Ben Z,Gao S,Wu W,et al.Clinical value of the VTIQ technology in the differential diagnosis of superficially enlarged lymph nodes[J].Acta Radiol,2018,59(7):836-844.
[4] Trottmann M,Marcon J,D'Anastasi M,et al.The role of VTIQ as a new tissue strain analytics measurement technique in testicular lesions[J].Clin Hemorheol Microcirc,2014,58(1):195-209.
[5] 李素淑,刘红梅,何燕妮,等.VTIQ技术评价健康青年人群跟腱弹性的重复性研究[J].中国超声医学杂志,2016,32(8):738-741.
[6] Ophir J,Céspedes I,Ponnekanti H,et al.Elastography:a quantitative method for imaging the elasticity of biological tissues[J].Ultrason Imaging,1991,13(2):111-134.
[7] Ianculescu V,Ciolovan LM,Dunant A,et al.Added value of Virtual Touch IQ shear wave elastography in the ultrasound assessment of breast lesions[J].Eur J Radiol,2014,83(5):773-777.
[8] Fierbinteanu-Braticevici C,Andronescu D,Usvat R,C et al.Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis[J].World J Gastroenterol,2009,15(44):5525-5532.
[9] Grgurevic I,Cikara I,Horvat J,et al.Noninvasive assessment of liver fibrosis with acoustic radiation force impulse imaging:increased liver and splenic stiffness in patients with liver fibrosis and cirrhosis[J].Ultraschall Med,2011,32(2):160-166.
[10] Goya C,Kilinc F,Hamidi C,et al.Acoustic radiation force impulse imaging for evaluation of renal parenchyma elasticity in diabetic nephropathy[J].AJR Am J Roentgenol,2015,204(2):324-329.
[11] Gennisson JL,Grenier N,Combe C,et al.Supersonic shear wave elastography of in vivo pig kidney:influence of blood pressure,urinary pressure and tissue anisotropy[J].Ultrasound Med Biol,2012,38(9):1559-1567.
[12] 李萍,顾莉红,李凤华,等.声脉冲辐射力成像技术在IgA肾病中的初步应用[J].中国超声医学杂志,2011,27(10):935-937.
[13] Lee J,Oh YT,Joo DJ,et al.Acoustic Radiation Force Impulse Measurement in Renal Transplantation:A Prospective,Longitudinal Study With Protocol Biopsies[J].Medicine (Baltimore),2015,94(39):e1590.
[14] Gya C,Daggulli M,Hamidi C,et al.The role of quantitative measurement by acoustic radiation force impulse imaging in differentiating benign renal lesions from malignant renal tumours[J].Radiol Med,2015,120(3):296-303.
[15] Habibi HA,Cicek RY,Kandemirli SG,et al.Acoustic radiation force impulse (ARFI) elastography in the evaluation of renal parenchymal stiffness in patients with ureteropelvic junction obstruction[J].J Med Ultrason,2017.44(2):167-172.
[16] 田飞,孟冬梅,王正滨,等.声辐射力脉冲成像技术对正常肾脏的定量研究[J].中华医学超声杂志(电子版),2012,9(10):910-914.
[17] Lee MJ,Kim MJ,Han KH,et al.Age-related changes in liver,kidney,and spleen stiffness in healthy children measured with acoustic radiation force impulse imaging[J].Eur J Radiol,2013,82(6):e290-294.
[18] Arda K,Ciledag N,Aktas E,et al.Quantitative assessment of normal soft-tissue elasticity using shear-wave ultrasound elastography[J].AJR Am J Roentgenol,2011,197(3):532-536.
[19] Golatta M,Schweitzer-Martin M,Harcos A,et al.Normal breast tissue stiffness measured by a new ultrasound technique:virtual touch tissue imaging quantification (VTIQ)[J].Eur J Radiol,2013,82(11):676-679.
[20] Tamaki K,Tamaki N,Kamada Y,et al.A non-invasive modality:the US virtual touch tissue quantification (VTTQ) for evaluation of breast cancer[J].Jpn J Clin Oncol,2013,43(9):889-895.
[21] Golatta M,Schweitzer-Martin M,Harcos A,et al.Evaluation of virtual touch tissue imaging quantification,a new shear wave velocity imaging method,for breast lesion assessment by ultrasound[J].Biomed Res Int,2014,2014:960262.
[2] He YP,Xu HX,Li XL,et al.Comparison of Virtual Touch Tissue Imaging & Quantification (VTIQ) and Toshiba shear wave elastography (T-SWE) in diagnosis of thyroid nodules:Initial experience[J].Clin Hemorheol Microcirc,2017,66(1):15-26.
[3] Ben Z,Gao S,Wu W,et al.Clinical value of the VTIQ technology in the differential diagnosis of superficially enlarged lymph nodes[J].Acta Radiol,2018,59(7):836-844.
[4] Trottmann M,Marcon J,D'Anastasi M,et al.The role of VTIQ as a new tissue strain analytics measurement technique in testicular lesions[J].Clin Hemorheol Microcirc,2014,58(1):195-209.
[5] 李素淑,刘红梅,何燕妮,等.VTIQ技术评价健康青年人群跟腱弹性的重复性研究[J].中国超声医学杂志,2016,32(8):738-741.
[6] Ophir J,Céspedes I,Ponnekanti H,et al.Elastography:a quantitative method for imaging the elasticity of biological tissues[J].Ultrason Imaging,1991,13(2):111-134.
[7] Ianculescu V,Ciolovan LM,Dunant A,et al.Added value of Virtual Touch IQ shear wave elastography in the ultrasound assessment of breast lesions[J].Eur J Radiol,2014,83(5):773-777.
[8] Fierbinteanu-Braticevici C,Andronescu D,Usvat R,C et al.Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis[J].World J Gastroenterol,2009,15(44):5525-5532.
[9] Grgurevic I,Cikara I,Horvat J,et al.Noninvasive assessment of liver fibrosis with acoustic radiation force impulse imaging:increased liver and splenic stiffness in patients with liver fibrosis and cirrhosis[J].Ultraschall Med,2011,32(2):160-166.
[10] Goya C,Kilinc F,Hamidi C,et al.Acoustic radiation force impulse imaging for evaluation of renal parenchyma elasticity in diabetic nephropathy[J].AJR Am J Roentgenol,2015,204(2):324-329.
[11] Gennisson JL,Grenier N,Combe C,et al.Supersonic shear wave elastography of in vivo pig kidney:influence of blood pressure,urinary pressure and tissue anisotropy[J].Ultrasound Med Biol,2012,38(9):1559-1567.
[12] 李萍,顾莉红,李凤华,等.声脉冲辐射力成像技术在IgA肾病中的初步应用[J].中国超声医学杂志,2011,27(10):935-937.
[13] Lee J,Oh YT,Joo DJ,et al.Acoustic Radiation Force Impulse Measurement in Renal Transplantation:A Prospective,Longitudinal Study With Protocol Biopsies[J].Medicine (Baltimore),2015,94(39):e1590.
[14] Gya C,Daggulli M,Hamidi C,et al.The role of quantitative measurement by acoustic radiation force impulse imaging in differentiating benign renal lesions from malignant renal tumours[J].Radiol Med,2015,120(3):296-303.
[15] Habibi HA,Cicek RY,Kandemirli SG,et al.Acoustic radiation force impulse (ARFI) elastography in the evaluation of renal parenchymal stiffness in patients with ureteropelvic junction obstruction[J].J Med Ultrason,2017.44(2):167-172.
[16] 田飞,孟冬梅,王正滨,等.声辐射力脉冲成像技术对正常肾脏的定量研究[J].中华医学超声杂志(电子版),2012,9(10):910-914.
[17] Lee MJ,Kim MJ,Han KH,et al.Age-related changes in liver,kidney,and spleen stiffness in healthy children measured with acoustic radiation force impulse imaging[J].Eur J Radiol,2013,82(6):e290-294.
[18] Arda K,Ciledag N,Aktas E,et al.Quantitative assessment of normal soft-tissue elasticity using shear-wave ultrasound elastography[J].AJR Am J Roentgenol,2011,197(3):532-536.
[19] Golatta M,Schweitzer-Martin M,Harcos A,et al.Normal breast tissue stiffness measured by a new ultrasound technique:virtual touch tissue imaging quantification (VTIQ)[J].Eur J Radiol,2013,82(11):676-679.
[20] Tamaki K,Tamaki N,Kamada Y,et al.A non-invasive modality:the US virtual touch tissue quantification (VTTQ) for evaluation of breast cancer[J].Jpn J Clin Oncol,2013,43(9):889-895.
[21] Golatta M,Schweitzer-Martin M,Harcos A,et al.Evaluation of virtual touch tissue imaging quantification,a new shear wave velocity imaging method,for breast lesion assessment by ultrasound[J].Biomed Res Int,2014,2014:960262.