Periostin在牙周膜作用的研究进展
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摘要
Periostin为一种细胞外基质蛋白,由成骨细胞及其前体细胞分泌。在骨膜及纤维结缔组织中表达,参与骨修复过程,有促进成骨及胶原纤维形成作用。在牙齿发育的帽状期及钟状期和牙齿萌出过程中,Periostin发挥着十分重要作用,特别是在牙周膜的修复再生中。Periostin还是机械应力下骨和牙周膜改建过程中的重要局部促进因素。本文就Periostin在牙周膜作用中的相关研究进展进行综述。
Periostin is an extracellular matrix proteins, secreted by the osteoblast and its precursor cells. It is expressed in periosteum and fibrous connective tissue and involved in bone repair. It can promote the formation of bone and collagen fibers. Periostin plays a very important role in the process of cap stage, bell stage, and tooth eruption, especially in the repair and regeneration of periodontal ligament. Periostin is also an impormant local promoting factor in bone and periodontal tissue reconstruction under mechanical sterss. The present paper reviews the related development of periostin reserach on the function of periodontal ligament.
Periostin is an extracellular matrix proteins, secreted by the osteoblast and its precursor cells. It is expressed in periosteum and fibrous connective tissue and involved in bone repair. It can promote the formation of bone and collagen fibers. Periostin plays a very important role in the process of cap stage, bell stage, and tooth eruption, especially in the repair and regeneration of periodontal ligament. Periostin is also an impormant local promoting factor in bone and periodontal tissue reconstruction under mechanical sterss. The present paper reviews the related development of periostin reserach on the function of periodontal ligament.
引文
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[2] 苗凯松,王禹基.POSTN的最新研究进展[J].医学综述,2014,20(19):3480-3482.
[3] 赵文华,叶银婷,李燕燕,等.骨膜蛋白在人牙周膜干细胞成纤维表达中的研究进展[J].口腔医学,2018,38(4):364-367.
[4] Maruhashi T,Kii I,Saito M,et al.Interaction between periostin and BMP-1 promotes proteoly tic activation of lysyl oxidase [J].J Biol Chem,2010,285(17):13294-13303.
[5] Kruzynska-Frejtag A,Wang J,Maeda M,et al.Periostin is expressed within the developing teeth at the sites of epithelial-mesenchymal interaction [J].J Dev Dyn,2004,229(4):857-868.
[6] Romanos GE,Asnani KP,Hingorani D,et al.PERIOSTIN:role in formation and maintenance of dental tissues [J].J Cell Physiol,2014,229(1):1-5.
[7] Du J,Li M.Functions of Periostin in dental tissues and its role in periodontal tissues regeneration [J].Cell Mol Life Sci,2017,74(23):4279-4286.
[8] Watanabe T,Yasue A,Fujihara S,et al.PERIOSTIN regulates MMP-2 expression via the alphavbeta3 integrin /ERK pathway in human periodontal ligament cells [J].J Arch Oral Biol,2012,57(1):52-59.
[9] Aukkarasongsup P,Haruyama N,Matsumoto T,et al.Periostin inhibits hypoxia-induced apoptosis in human periodontal ligament cells via TGF-β signaling [J].Biochem Biophys Res Commun,2013,441(1):126-132.
[10] Liu Y,Du L.Role of pancreatic stellate cells and periostin in pancreatic cancer progression [J].Tumour Biol,2015,36(5):3171-3177.
[11] 吕琳琳,李纾.骨膜蛋白与牙周组织再生[J].国际口腔医学杂志,2014,41(2):224-227.
[12] 蒋一.Periostin在高糖条件下牙周组织中的表达及胰岛素干预调控的研究[D].中国人民解放军医学院,2013.
[13] Padial-Molina M,Volk SL,Taut AD,et al.Periostin is down-regulated during periodontal inflammation [J].J Dent Res,2012,91(11):1078-1084.
[14] Wen W,Chau E,Jackson-Boeters L,et al.TGF-β1 and FAK regulate periostin expression in PDL fibroblasts [J].J Dent Res,2010,89(12):1439-1443.
[15] Rios H,Koushik SV,Wang H,et al.Periostin null mice exhibit dwarfism,incisor enamel defects,and an early-onset periodontal disease-like phenotype [J].Mol Cell Biol,2005,25(24):11131-11144.
[16] Foster BL,Soenjaya Y,Nociti FH Jr,et al.Deficiency in acellular cementum and periodontal attachment in bsp null mice [J].J Dent Res,2013,92(2):166-172.
[17] Tabata C,Hongo H,Sasaki M,et al.Altered distribution of extracellular matrix proteins in the periodontal ligament of periostin-deficient mice [J].Histol Histopathol,2014,29(6):731-742.
[18] Afanador E,Yokozeki M,Oba Y,et al.Messenger RNA expression of periostin and Twist transiently decrease by occlusal hypofunction in mouse periodontal ligament [J].Arch Oral Biol,2005,50(12):1023-1031.
[19] Xu HY,Nie EM,Deng G,et al.Periostin is essential for periodontal ligament remodeling during orthodontic treatment [J].Mol Med Rep,2017,15(4):1800-1806.
[20] Choi JW,Arai C,Ishikawa M,et al.Fiber system degradation,and periostin and connective tissue growth factor level reduction,in the periodontal ligament of teeth in the absence of masticatory load [J].J Periodontal Res,2011,46(5):513-521.
[21] Washio K,Iwata T,Mizutani M,et al.Assessment of cell sheets derived from human periodontal ligament cells:a pre-clinical study [J].Cell Tissue Res,2010,341(3):397-404.
[22] Galli C,Piergianni M,Piemontese M,et al.Periostin improves cell adhesion to implantable biomaterials and osteoblastic differentiation on implant titanium surfaces in a topography-dependent fashion [J].J Biomed Mater Res A,2014,102(11):3855-3861.
[23] Wu Z,Dai W,Wang P,et al.Periostin promotes migration,proliferation,and differentiation of human periodontal ligament mesenchymal stem cells [J].Connect Tissue Res,2018,59(2):108-119.
[24] Park CH,Rios HF,Jin Q,et al.Giannobile WV Tissue engineering bone-ligament complexes using fiber-guiding scaffolds [J].Biomaterials,2012,33(1):137-145.
[25] Berahim Z,Moharamzadeh K,Jowett AK,et al.Evaluation of osteogenic and cementogenic potential of periodontal ligament fibroblast spheroids using a three-dimensional in vitro model of periodontium [J].Int J Dent,2015,2015:605813.
[26] Panduwawala CP,Zhan X,Dissanayaka WL,et al.In vivo periodontal tissue regeneration by periodontal ligament stem cells and endothelial cells in three-dimensional cell sheet constructs [J].J Periodontal Res,2017,52(3):408-418.
[27] Padial-Molina M,Volk SL,Rios HF.Preliminary insight into the Periostin leverage during periodontal tissue healing [J].J Clin Periodontol,2015,42(8):764-772.
[28] Maruhashi T,Kii I,Saito M,Kudo A.Interaction between periostin and BMP-1 promotes proteolytic activation of lysyl oxidase [J].J Biol Chem,2010,285(17):13294-13303.
[2] 苗凯松,王禹基.POSTN的最新研究进展[J].医学综述,2014,20(19):3480-3482.
[3] 赵文华,叶银婷,李燕燕,等.骨膜蛋白在人牙周膜干细胞成纤维表达中的研究进展[J].口腔医学,2018,38(4):364-367.
[4] Maruhashi T,Kii I,Saito M,et al.Interaction between periostin and BMP-1 promotes proteoly tic activation of lysyl oxidase [J].J Biol Chem,2010,285(17):13294-13303.
[5] Kruzynska-Frejtag A,Wang J,Maeda M,et al.Periostin is expressed within the developing teeth at the sites of epithelial-mesenchymal interaction [J].J Dev Dyn,2004,229(4):857-868.
[6] Romanos GE,Asnani KP,Hingorani D,et al.PERIOSTIN:role in formation and maintenance of dental tissues [J].J Cell Physiol,2014,229(1):1-5.
[7] Du J,Li M.Functions of Periostin in dental tissues and its role in periodontal tissues regeneration [J].Cell Mol Life Sci,2017,74(23):4279-4286.
[8] Watanabe T,Yasue A,Fujihara S,et al.PERIOSTIN regulates MMP-2 expression via the alphavbeta3 integrin /ERK pathway in human periodontal ligament cells [J].J Arch Oral Biol,2012,57(1):52-59.
[9] Aukkarasongsup P,Haruyama N,Matsumoto T,et al.Periostin inhibits hypoxia-induced apoptosis in human periodontal ligament cells via TGF-β signaling [J].Biochem Biophys Res Commun,2013,441(1):126-132.
[10] Liu Y,Du L.Role of pancreatic stellate cells and periostin in pancreatic cancer progression [J].Tumour Biol,2015,36(5):3171-3177.
[11] 吕琳琳,李纾.骨膜蛋白与牙周组织再生[J].国际口腔医学杂志,2014,41(2):224-227.
[12] 蒋一.Periostin在高糖条件下牙周组织中的表达及胰岛素干预调控的研究[D].中国人民解放军医学院,2013.
[13] Padial-Molina M,Volk SL,Taut AD,et al.Periostin is down-regulated during periodontal inflammation [J].J Dent Res,2012,91(11):1078-1084.
[14] Wen W,Chau E,Jackson-Boeters L,et al.TGF-β1 and FAK regulate periostin expression in PDL fibroblasts [J].J Dent Res,2010,89(12):1439-1443.
[15] Rios H,Koushik SV,Wang H,et al.Periostin null mice exhibit dwarfism,incisor enamel defects,and an early-onset periodontal disease-like phenotype [J].Mol Cell Biol,2005,25(24):11131-11144.
[16] Foster BL,Soenjaya Y,Nociti FH Jr,et al.Deficiency in acellular cementum and periodontal attachment in bsp null mice [J].J Dent Res,2013,92(2):166-172.
[17] Tabata C,Hongo H,Sasaki M,et al.Altered distribution of extracellular matrix proteins in the periodontal ligament of periostin-deficient mice [J].Histol Histopathol,2014,29(6):731-742.
[18] Afanador E,Yokozeki M,Oba Y,et al.Messenger RNA expression of periostin and Twist transiently decrease by occlusal hypofunction in mouse periodontal ligament [J].Arch Oral Biol,2005,50(12):1023-1031.
[19] Xu HY,Nie EM,Deng G,et al.Periostin is essential for periodontal ligament remodeling during orthodontic treatment [J].Mol Med Rep,2017,15(4):1800-1806.
[20] Choi JW,Arai C,Ishikawa M,et al.Fiber system degradation,and periostin and connective tissue growth factor level reduction,in the periodontal ligament of teeth in the absence of masticatory load [J].J Periodontal Res,2011,46(5):513-521.
[21] Washio K,Iwata T,Mizutani M,et al.Assessment of cell sheets derived from human periodontal ligament cells:a pre-clinical study [J].Cell Tissue Res,2010,341(3):397-404.
[22] Galli C,Piergianni M,Piemontese M,et al.Periostin improves cell adhesion to implantable biomaterials and osteoblastic differentiation on implant titanium surfaces in a topography-dependent fashion [J].J Biomed Mater Res A,2014,102(11):3855-3861.
[23] Wu Z,Dai W,Wang P,et al.Periostin promotes migration,proliferation,and differentiation of human periodontal ligament mesenchymal stem cells [J].Connect Tissue Res,2018,59(2):108-119.
[24] Park CH,Rios HF,Jin Q,et al.Giannobile WV Tissue engineering bone-ligament complexes using fiber-guiding scaffolds [J].Biomaterials,2012,33(1):137-145.
[25] Berahim Z,Moharamzadeh K,Jowett AK,et al.Evaluation of osteogenic and cementogenic potential of periodontal ligament fibroblast spheroids using a three-dimensional in vitro model of periodontium [J].Int J Dent,2015,2015:605813.
[26] Panduwawala CP,Zhan X,Dissanayaka WL,et al.In vivo periodontal tissue regeneration by periodontal ligament stem cells and endothelial cells in three-dimensional cell sheet constructs [J].J Periodontal Res,2017,52(3):408-418.
[27] Padial-Molina M,Volk SL,Rios HF.Preliminary insight into the Periostin leverage during periodontal tissue healing [J].J Clin Periodontol,2015,42(8):764-772.
[28] Maruhashi T,Kii I,Saito M,Kudo A.Interaction between periostin and BMP-1 promotes proteolytic activation of lysyl oxidase [J].J Biol Chem,2010,285(17):13294-13303.