八角茴香精馏釜底残液的分离纯化及鉴定
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摘要
目的:对八角茴香精馏釜底残液中化学成分进行研究。方法:取八角茴香精馏釜底残液950 g,以环己烷-乙酸乙酯经硅胶柱梯度洗脱,再进行重结晶,根据NMR、MS、IR等波谱数据和旋光值等理化性质鉴定化合物的结构。结果:从八角茴香精馏釜底残液中分离了一个化合物,鉴定为3,6-二羟基-1-薄荷烯。
Objective: Research on chemical composition of residue of star anise rectifying tank bottom.Methods: 950 g was taken from residue of star anise rectifying tank bottom, Gradiented elution through silica gel column with cyclohexane-Ethyl acetate mixed solution, Recrystallization, Identified the structure of the compound according to spectral data and optical rotation value of NMR, MS, IR, etc. Result: A compound that was identified as 3,6-two hydroxyl-1-menthene was isolated from the residue of star anise rectifying tank.
Objective: Research on chemical composition of residue of star anise rectifying tank bottom.Methods: 950 g was taken from residue of star anise rectifying tank bottom, Gradiented elution through silica gel column with cyclohexane-Ethyl acetate mixed solution, Recrystallization, Identified the structure of the compound according to spectral data and optical rotation value of NMR, MS, IR, etc. Result: A compound that was identified as 3,6-two hydroxyl-1-menthene was isolated from the residue of star anise rectifying tank.
引文
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[2]Scopel R,Da Silva C F,Lucas A M,et al.Fluid phase equilibria and mass transfer studies applied to supercritical fluid extraction of Illicium verum volatile oil[J].Fluid Phase Equilibria,2016,417:203-211.
[3]刘永华.广西八角产业可持续发展的SWOT分析[J].广西农学报,2013,28(2):77-80.
[4]马锦林,曾祥艳,李开祥,等.广西八角产业现状及发展战略[J].广西林业科学,2011,40(4):336-339.
[5]黄丽贞,谢滟,姜露,等.八角茴香化学与药理研究进展[J].辽宁中医药大学学报,2015,17(2):83-85.
[6]袁经权,周小雷,王硕,等.八角茴香化学成分的研究[J].中成药,2010,32(12):2123-2126.
[7]Wang G W,Hu W T,Huang B K,et al.Illicium verum:A review on its botany,traditional use,chemistry and pharmacology[J].J Ethnopharmacol,2011,136(1):10-20.
[8]Chouksey D,Sharma P,Pawar R S.Biological activities and chemical constituents of Illicium verum hook fruits(Chinese star anise)[J].Pharm Sin,2010,1(3):1-10.
[9]钟昌勇,周宗明,刘虹.广西大茴香油的生产、加工和贸易现状[J].广西林业科学,2007,36(3):173-176.
[10]林葵,谢集照,张思敏,等.八角茴香油精馏釜底残液中1个新的苯甲醛类化合物[J].中草药,2015,46(10):1423-1425.